Response to acute ibuprofen exposure (Daphnia magna)

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1Starch andsucrosemetabolismCarbohydratemetabolism1,2 DiacylglycerolGlyPamyAGlycolysisFructose andmannosemetabolismEnoMANALipidmetabolismGlycerolipidmetabolismLipFatty acidmetabolismACSGlycerophospholipidmetabolismCTPPhospahtidylcholineGPXEicosanoidmetabolismCOXLtb4dhACSPPAR signallingpathwayFABP3RXRVDAC2Calcium signallingpathwaySignaltransduction


Pathway that describes the biological response found in Daphnia magna after exposure to ibuprofen. Warning: Gene identifiers are based on the full names in the Additional File 1 as the article does not contains accession numbers for the Daphnia genes. Search in Ensembl returned on several occasions multiple potential hits where one was randomly selected.

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  1. Heckmann LH, Sibly RM, Connon R, Hooper HL, Hutchinson TH, Maund SJ, Hill CJ, Bouetard A, Callaghan A; ''Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna.''; Genome Biol, 2008 PubMed Europe PMC Scholia


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122821view16:32, 21 May 2022EgonwModified description
122820view16:29, 21 May 2022EgonwMore gene identifiers
122819view14:01, 21 May 2022MaintBotAdded the first three gene variants (using Additional file 1)
116342view12:46, 2 May 2021L DupuisConnected lines
116164view15:45, 14 April 2021EgonwMore content
116124view06:36, 13 April 2021EgonwAdded a first identifier
116123view06:35, 13 April 2021EgonwAnother bit of the pathway
116109view14:48, 12 April 2021EgonwOntology Term : 'drug pathway' added !
116108view14:48, 12 April 2021EgonwModified description
116104view14:44, 12 April 2021EgonwHandset the species
116103view14:42, 12 April 2021EgonwNew pathway

External references


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NameTypeDatabase referenceComment
1,2 DiacylglycerolMetaboliteCHEBI:49172 (ChEBI)
ACSGeneProductAPZ42_024578 (Ensembl)
EnoGeneProductAPZ42_018388 (Ensembl)
FABP3GeneProductAPZ42_014858 (Ensembl)
GPXGeneProductAPZ42_030648 (Ensembl)
GlyPGeneProductAPZ42_020436 (Ensembl)
LipGeneProductAPZ42_029151 (Ensembl)
MANAGeneProductAPZ42_024669 (Ensembl)
PhospahtidylcholineMetaboliteCHEBI:64482 (ChEBI)
VDAC2GeneProductAPZ42_018910 (Ensembl)
amyAGeneProductAPZ42_021009 (Ensembl)

Annotated Interactions

No annotated interactions

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