Neolacto series sphingolipid metabolism (Homo sapiens)

From WikiPathways

Jump to: navigation, search
2, 3nLc6Ceri antigen B4GALT3H1 glycolipid, type II antigenFUCA1Lc3CerSSEA-1, Lex-5SialosylparaglobosideFUT1Type II A antigenST3GAL4nLc5CerFUT2B3GNT5Sialyl LeXNAGANEU2FUT5B4GALT4NeuAcα2-8NeuAcα2-3Galβ1-4GlcNAcβ1-3Galβ1-4Glcβ-CernLc4CerB4GALT1LacCerB3GNT5


Description

Ganglio- series of glycosphingolipids, biosynthesis

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

  1. Yamashiro S, Haraguchi M, Furukawa K, Takamiya K, Yamamoto A, Nagata Y, Lloyd KO, Shiku H; ''Substrate specificity of beta 1,4-N-acetylgalactosaminyltransferase in vitro and in cDNA-transfected cells. GM2/GD2 synthase efficiently generates asialo-GM2 in certain cells.''; J Biol Chem, 1995 PubMed Europe PMC Scholia
  2. ''Handbook of Glycosyltransferases and Related Genes''; doi.org/10.1007/978-4-431-67877-9, 2002
  3. Merril AH Jr; ''SphinGOMAP--a web-based biosynthetic pathway map of sphingolipids and glycosphingolipids.''; Glycobiology, 2005 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
134478view01:04, 22 July 2024EweitzFix truncated label in node
134477view01:04, 22 July 2024EweitzFix truncated labels in nodes, improve node alignment
124624view14:24, 17 November 2022Conroy lipidsanother metabolight
124623view13:47, 17 November 2022Conroy lipidsa couple more steps from sphingomap- no synthesis data available in rhea
124619view15:52, 16 November 2022Conroy lipidsOntology Term : 'glycosphingolipid metabolic pathway' added !
124618view15:52, 16 November 2022Conroy lipidsOntology Term : 'lipid metabolic pathway' added !
124617view15:52, 16 November 2022Conroy lipidsOntology Term : 'PW:0000164' removed !
124616view15:34, 16 November 2022Conroy lipids
124615view15:22, 16 November 2022Conroy lipidsNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
B3GNT5GeneProductQ9BYG0 (Uniprot-TrEMBL)
B4GALT1GeneProductP15291 (Uniprot-TrEMBL)
B4GALT3GeneProductO60512 (Uniprot-TrEMBL)
B4GALT4GeneProductO60513 (Uniprot-TrEMBL)
FUCA1GeneProductP04066 (Uniprot-TrEMBL)
FUT1GeneProductP19526 (Uniprot-TrEMBL)
FUT2GeneProductQ10981 (Uniprot-TrEMBL)
FUT5GeneProductQ11128 (Uniprot-TrEMBL)
H1 glycolipid, type II antigenMetaboliteLMSP0505AD00 (LIPID MAPS)
LacCerMetaboliteLMSP0501AB00 (LIPID MAPS)
Lc3CerMetaboliteLMSP0504AA00 (LIPID MAPS)
NAGAGeneProductP17050 (Uniprot-TrEMBL)
NEU2GeneProductQ9Y3R4 (Uniprot-TrEMBL)
NeuAcα2-8NeuAcα2-3Galβ1-4GlcNAcβ1-3Galβ1-4Glcβ-CerMetaboliteLMSP0601EG00 (LIPID MAPS)
SSEA-1, Lex-5MetaboliteLMSP0505AB00 (LIPID MAPS)
ST3GAL4GeneProductQ11206 (Uniprot-TrEMBL)
SialosylparaglobosideMetaboliteLMSP0601EF00 (LIPID MAPS)
Sialyl LeXMetaboliteLMSP0601EE00 (LIPID MAPS)
Type II A antigenMetaboliteLMSP0505AF00 (LIPID MAPS)
nLc4CerMetaboliteLMSP0505AA00 (LIPID MAPS) ChEBI 17292, Smap 8
nLc5CerMetaboliteLMSP0505AK00 (LIPID MAPS)
nLc6Cer i antigen MetaboliteLMSP0505AL00 (LIPID MAPS)

Annotated Interactions

View all...
SourceTargetTypeDatabase referenceComment
H1 glycolipid, type II antigennLc4Cermim-conversion48225 (Rhea)
LacCerLc3Cermim-conversion13906 (Rhea)
Lc3CernLc4Cermim-conversion31500 (Rhea)
SialosylparaglobosidenLc4Cermim-conversion47853 (Rhea)
Type II A antigenH1 glycolipid, type II antigenmim-conversion48213 (Rhea)
nLc4CerH1 glycolipid, type II antigenmim-conversion48305 (Rhea)
nLc4CerSSEA-1, Lex-5mim-conversion48333 (Rhea)
nLc4CerSialosylparaglobosidemim-conversion18914 (Rhea)
nLc4CernLc5Cermim-conversion23005 (Rhea)
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5302"
Personal tools