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  • Pathway:WP4415
    ... to TrkA-positive cutaneous sensory neurons. Runx3 expression in chick and mouse embryos is restricted to ventro-lateral domain of the dorsal root ganglion ... ... action with CBFB (Otto et al. 1997, Lee et al. 1997, Otto et al. 2002). In mouse cleidocranial dysplasia models, the physical and functional interaction be ...
    388 KB (46676 words) - 16:11, 25 January 2021
  • Pathway:WP1822
    ... . 2005, Alvarez-Saavedra 2007, Van Esch et al. 2012). The phenotype of the mouse model of the MECP2 duplication syndrome in adult mice is reversible when M ... ... inflammatory responses (Dominguez-Soto et al. 2005). RUNX3 is involved in mouse TGF-beta-mediated dendritic cell function and its deficiency is linked to ...
    726 KB (85515 words) - 12:37, 22 May 2021
  • Pathway:WP2738
    ... acterized in human cells but is inferred from properties of the homologous mouse proteins. The stoichiometry of this complex is unknown (Cui et al. 2003).& ... ... egulation of type I Runx2 mediated by dexamethasone is required for 3T3-L1 adipogenesis.</bp:TITLE>
    93 KB (11670 words) - 16:49, 25 January 2021
  • Pathway:WP2586
    ... a#string">NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis.</bp:TITLE> ... epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster.</bp:TITLE>
    158 KB (18160 words) - 20:59, 5 May 2023
  • Pathway:WP2720
    ... nervous system by influencing the differentiation of astrocytes, based on mouse studies.</Comment> ... d on mouse studies, is implicated in many developmental processes, such as adipogenesis, hematopoiesis, differentiation of adrenal gland and other neuroendocrine ...
    522 KB (58148 words) - 17:03, 25 January 2021
  • Pathway:WP2751
    ... d activate transcription of CEBPA, one of the key transcription factors in adipogenesis. A current hypothesis posits a self-reinforcing loop that maintains PPARG ... ... translated to yield protein. Expression of Perilipin is upregulated during adipogenesis.</Comment>
    162 KB (18197 words) - 12:48, 9 May 2021
  • Pathway:WP3226
    ... epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster.</bp:TITLE> ... a#string">NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis.</bp:TITLE>
    164 KB (18902 words) - 10:59, 21 May 2021
  • Pathway:WP4085
    ... oxicity observed in doxorubicin-treated patients (Olson et al. 1998). In a mouse model, carbonyl reductase [NADPH] 3 (Cbr3) is able to catalyse the NADPH-d ... ... al assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns.</bp:TITLE>
    791 KB (84485 words) - 15:39, 9 October 2020
  • Pathway:WP3839
    ... ferator activated receptor gamma (PPAR-gamma). Ablation of RETSAT inhibits adipogenesis but this block was not overcome by the product of RETSAT enzymatic activit ... ... 001/XMLSchema#string">Rapid initial removal of chylomicron remnants by the mouse liver does not require hepatically localized apolipoprotein E.</bp:TITLE>
    239 KB (26373 words) - 16:15, 25 January 2021
  • Pathway:WP4105
    ... to TrkA-positive cutaneous sensory neurons. Runx3 expression in chick and mouse embryos is restricted to ventro-lateral domain of the dorsal root ganglion ... ... ely regulated by Wnt4 signaling (Naillat et al. 2015).&lt;br&gt;Studies in mouse hematopoietic stem and progenitor cells imply that RUNX1 may be a direct t ...
    490 KB (57231 words) - 16:12, 25 January 2021
  • Pathway:WP4114
    ... CFA) (Watkins et al. 2007). The activity of human SLC27A3 is inferred from mouse Slc27a3 functional studies (Pei et al. 2004).</Comment> ... formation of CIT to Ac-CoA and and plays an essential role in lipogenesis, adipogenesis and differentiation of 3T3-L1 preadipocytic cells (Elshourbagy et al. 1992 ...
    176 KB (19430 words) - 16:25, 25 January 2021
  • Pathway:WP4414
    ... eacetylase HDAC1 to the RUNX2 promoter (Zhang et al. 2012). Similar to the mouse promoter, human RUNX2 P2 promoter also contains GREs. </Comment> ... RUNX2 (Zhao et al. 2003). While the direct interaction was demonstrated in mouse cells, it was shown that in human cells RUNX2 stability is increased upon ...
    234 KB (25282 words) - 17:05, 25 January 2021
  • Pathway:WP4421
    ... ://www.w3.org/2001/XMLSchema#string">Reduction of all-trans-retinal in the mouse liver peroxisome fraction by the short-chain dehydrogenase/reductase RRD: ... ... suppresses obesity both by promoting energy expenditure and by inhibiting adipogenesis.</bp:TITLE>
    171 KB (19408 words) - 01:58, 22 May 2024
  • Pathway:WP5001
    ... of CEBPB, which interferes with repression of MYC by CEBPA (inferred from mouse homologs in Zhang et al. 2010) and represses MYC less than CEBPA does (Hir ... ... pho-CREB1 and phospho-STAT3 activate transcription of CEBPB (inferred from mouse homologs).</Comment>
    183 KB (21015 words) - 16:44, 25 January 2021

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