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• Pathway:WP4415
  ... to TrkA-positive cutaneous sensory neurons. Runx3 expression in chick and mouse embryos is restricted to ventro-lateral domain of the dorsal root ganglion ... ... action with CBFB (Otto et al. 1997, Lee et al. 1997, Otto et al. 2002). In mouse cleidocranial dysplasia models, the physical and functional interaction be ...
  388 KB (46676 words) - 16:11, 25 January 2021
• Pathway:WP722
  10854065 (CellType: spermatid) Moreover, in mouse spermatids, i.e., the haploid cytodifferentiating cells, a so far unidenti ... ... g/2001/XMLSchema#string">Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes.</bp:TI ...
  709 KB (96586 words) - 14:31, 9 March 2023
• Pathway:WP727
  Stimulation of 5-HT Uptake in Mouse Synaptosomes by IL-1 b and TNFa To assess the relevanc e o f o u r finding ... ... g/2001/XMLSchema#string">Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes.</bp:TI ...
  107 KB (12413 words) - 00:36, 16 July 2024
• Pathway:WP734
  10854065 (CellType: spermatid) Moreover, in mouse spermatids, i.e., the haploid cytodifferentiating cells, a so far unidenti ... ... ema#string">The PKA/CREB pathway is closely involved in VEGF expression in mouse macrophages.</bp:TITLE>
  180 KB (24396 words) - 16:06, 6 March 2023
• Pathway:WP732
  <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A mouse CDC25-like product enhances the formation of the active GTP complex of hum ... ... datatype="http://www.w3.org/2001/XMLSchema#string">Mek2 is dispensable for mouse growth and development.</bp:TITLE>
  183 KB (24555 words) - 01:10, 30 July 2024
• Pathway:WP1763
  ... to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As sta ... ... rk: An Electronic Representation of the Network Underlying Pluripotency in Mouse, and Its Applications. PLoS ONE 5(12): e15165. doi:10.1371/journal.pone.00 ...
  741 KB (73570 words) - 19:29, 26 April 2023
• Pathway:WP1784
  ... ase-3 was found to be responsible for TJP1 (ZO-1) cleavage in both dog and mouse cells (Chin et al. 2006, Zehendner et al. 2011).</Comment>
  247 KB (26670 words) - 16:34, 25 January 2021
• Pathway:WP1785
  ... pe of glutamine:fructose-6-phosphate amidotransferase (GFAT2) in human and mouse.</bp:TITLE> ... overexpressing or eliminating N-acetylglucosaminyltransferase-TIII in the mouse.</bp:TITLE>
  552 KB (62663 words) - 16:59, 25 January 2021
• Pathway:WP2742
  ... RF1 to the cytosol (Suzuki et al. 2002, Tajima et al. 2003). A recombinant mouse Smad7 and recombinant human SMURF1 were used in these experiments.</Commen ... ... et al. 2004). This was deduced based on experiments involving recombinant mouse Smad7 and recombinant human PPP1R15A, TGFBR1, TGFBR2 and SARA.</Comment>
  325 KB (36015 words) - 01:48, 22 May 2024
• Pathway:WP1794
  ... nts a third protein of the Ang family that binds to the Tie2 receptor. The mouse Ang3 and human Ang4 are interspecies orthologs. Ang4 acts as an activating ... ... XMLSchema#string">Analysis of glycoprotein E-selectin ligands on human and mouse marrow cells enriched for hematopoietic stem/progenitor cells.</bp:TITLE>
  520 KB (57910 words) - 15:56, 9 October 2020
• Pathway:WP1799
  ... ant isoform in brain and testes. All 3 isoforms are expressed in human and mouse platelets (Yin et al. 2008; O'Brien et al. 2008). Note: all data in the pa ...
  309 KB (34357 words) - 16:56, 25 January 2021
• Pathway:WP1809
  ... er than Rap (Kawasaki et al. 1998, Ebinu et al. 1998).&lt;br&gt; &lt;br&gt;Mouse platelets that lack CalDAG-GEFI are severely compromised in integrin-depen ...
  67 KB (7535 words) - 16:07, 25 January 2021
• Pathway:WP1822
  ... . 2005, Alvarez-Saavedra 2007, Van Esch et al. 2012). The phenotype of the mouse model of the MECP2 duplication syndrome in adult mice is reversible when M ... ... inflammatory responses (Dominguez-Soto et al. 2005). RUNX3 is involved in mouse TGF-beta-mediated dendritic cell function and its deficiency is linked to ...
  726 KB (85515 words) - 12:37, 22 May 2021
• Pathway:WP1823
  ... ki-Inoue et al. 2004). GPVI signalling requires the FCeRIgamma chain while mouse knockouts suggest it is not required for GPIbR signalling (Kaiser-Friede e ...
  45 KB (5215 words) - 09:11, 7 May 2021
• Pathway:WP1826
  ... The same group also reported that PP2 does not inhibit phosphorylation of mouse Clec1b by rhodocytin, in contrast to the reported effect in human platelet ... ... Vav family proteins are involved in filopodia and lamellipodia formation; mouse platelets deficient in Vav1 and Vav3 exhibit reduced filopodia and lamelli ...
  165 KB (18468 words) - 16:12, 25 January 2021
• Pathway:WP1829
  ... une arthritis. Correspondingly, anti-PILRa mAb ameliorated inflammation in mouse arthritis models and suppressed the production of proinflammatory cytokine ... ... and, but the binding affinity of PILRB is much lower (Tabata et al. 2008). Mouse NK cells expressing PILRB mediate cytotoxicity against CD99-positive targe ...
  607 KB (68800 words) - 12:54, 22 May 2021
• Pathway:WP1843
  <Comment Source="Reactome">Heat-stable antigen (HSA/mouse CD24) is expressed in both haematopoietic and neural cells. HSA binds to L ...
  348 KB (37212 words) - 16:45, 25 January 2021
• Pathway:WP2738
  ... acterized in human cells but is inferred from properties of the homologous mouse proteins. The stoichiometry of this complex is unknown (Cui et al. 2003).& ... ... o distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene.</bp:TITLE>
  93 KB (11670 words) - 16:49, 25 January 2021
• Pathway:WP1919
  ... orylated tyrosine numbering in human BCAR1 is based on similarity with the mouse p130Cas.</Comment> ... tion. Phosphorylation of Axl tyrosine residues 772 and 814 (773 and 815 in mouse) is required for VEGFA-dependent binding of the p85-subunit of PI3K and ac ...
  652 KB (72121 words) - 16:22, 25 January 2021
• Pathway:WP1929
  ... ugh this is not the case for mouse. PAR2 is not expressed in platelets. In mouse platelets, Gq is necessary for platelet secretion and aggregation in respo ...
  140 KB (15142 words) - 09:42, 7 May 2021

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