Portal:CPTAC/Hallmark/Proliferative

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*[[Pathway:WP4553]] FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma
*[[Pathway:WP4553]] FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma
*[[Pathway:WP4566]] Translation inhibitors in chronically activated PDGFRA cells
*[[Pathway:WP4566]] Translation inhibitors in chronically activated PDGFRA cells
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*[[Pathway:WP4541]] Hippo-Merlin Signaling Dysregulation

Revision as of 18:17, 10 October 2019

The normal control of cell growth and division in cells is governed by careful control and release of growth-promoting signals, but in cancer cells this control is deregulated. Signaling through growth factors via the tyrosine kinase domains of cell-surface receptors, trigger progression through the cell cycle and other pathways. (Adapted from Hallmarks of cancer: the next generation, Hanahan and Weinberg, Cell 2011)

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