Portal:CPTAC/Hallmark/Proliferative

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Current revision (00:11, 11 October 2019) (view source)
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*[[Pathway:WP3997]]
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The normal control of cell growth and division in cells is governed by careful control and release of growth-promoting signals, but in cancer cells this control is deregulated.
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*[[Pathway:WP3980]]
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Signaling through growth factors via the tyrosine kinase domains of cell-surface receptors, trigger progression through the cell cycle and other pathways. (Adapted from [https://www.ncbi.nlm.nih.gov/pubmed/21376230 Hallmarks of cancer: the next generation, Hanahan and Weinberg, Cell 2011])
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*[[Pathway:WP3624]]
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*[[Pathway:WP3972]] PDGFR-beta pathway
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*[[Pathway:WP3632]]
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*[[Pathway:WP673]] ErbB Signaling Pathway
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*[[Pathway:WP4010]]
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*[[Pathway:WP581]] EPO Receptor Signaling
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*[[Pathway:WP4011]]
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*[[Pathway:WP382]] MAPK Signaling Pathway
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*[[Pathway:WP4017]]
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*[[Pathway:WP4223]] Ras Signaling
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*[[Pathway:WP4026]]
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*[[Pathway:WP4205]] MET in type 1 papillary renal cell carcinoma
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*[[Pathway:WP313]] Signaling of Hepatocyte Growth Factor Receptor
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*[[Pathway:WP4553]] FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma
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*[[Pathway:WP4566]] Translation inhibitors in chronically activated PDGFRA cells
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*[[Pathway:WP4541]] Hippo-Merlin Signaling Dysregulation

Current revision

The normal control of cell growth and division in cells is governed by careful control and release of growth-promoting signals, but in cancer cells this control is deregulated. Signaling through growth factors via the tyrosine kinase domains of cell-surface receptors, trigger progression through the cell cycle and other pathways. (Adapted from Hallmarks of cancer: the next generation, Hanahan and Weinberg, Cell 2011)

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