Serotonin HTR1 group and FOS pathway (Homo sapiens)

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26210, 28, 44, 104, 127...43, 107, 146, 155, 166...1, 84, 91, 226, 35114, 148, 151, 156, 202...3433851, 169, 187, 223, 275...25225026222, 68, 73, 103, 243...2403852, 83, 21735, 100, 126, 171, 190...21613811, 18, 24, 43, 108...31, 97, 135, 139, 253...20, 60, 215, 229, 239...28726231634340, 42, 48, 149, 162...15, 39, 66, 101, 117...92, 125, 159, 188, 3157, 289, 31631474, 128, 181, 22263, 76, 102, 124, 161...1234313626, 27, 31, 55, 59...50, 129, 147, 150, 211...24616, 65, 130, 163, 235343132, 20026212034323, 30, 54, 58, 77...13, 29, 47, 56, 122...69, 168, 214, 29836, 106, 134, 180, 244113, 34333, 80, 88, 96, 111...288, 29534330, 41, 75, 98, 142...9, 21, 32, 110, 114...82, 160, 337, 352192, 350195, 203, 230, 3368, 57, 87, 157, 164...25, 109, 167, 269, 271...61, 70, 133, 184, 236...3182, 2615, 17, 19, 45, 53...20578, 105, 112, 189, 2102, 6, 49, 116, 119...240123, 19162, 140, 296, 335, 33934371, 89, 94, 99, 144...158, 249, 255, 301, 30879, 95, 121, 153, 199...3434, 28234, 231, 32837, 185, 212, 304Indirect RegulationSmall MoleculeProtein ModificationReceptorDirect RegulationSynthesis Promoter BindingProteinBindingLEGENDFunctional Protein ClassGb/gCALCIUMPDPK1MAPKAPK3MAPK1HTR1E1,2-DiacetinPKC1,4,5-Insp3MAPKAPK2RASGRF1SRFBRAFFOSSerotoninGNAO1MAP2K3ITPR1RPS6KMAP2K6HTR1FRasRASGRP1GNAI2ELK1HTR1BGNAI1CREB1RAP1ARPS6KA5MAP2K1HTR1ARHOAMAP3K1MAPK14ELK4MAP2K2MAPK3HTR1DPI3KPtdIns3PGNAI3PLC


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History

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CompareRevisionActionTimeUserComment
125764view14:31, 9 March 2023DeSlAdded rhea ID and ref. for PI3K interaction
125763view14:27, 9 March 2023DeSlFixed PI3K enzyme conversion
125656view15:59, 6 March 2023DeSlIntegrated description from WP733
125655view15:58, 6 March 2023DeSlIntegrated WP733
125651view15:51, 6 March 2023DeSlAdded two annotations
125650view15:47, 6 March 2023DeSlConverted (in)direct regulation to MIM-stimulation
125649view15:43, 6 March 2023DeSlVretical layout, converted arrow to MIM-conversion
125648view15:41, 6 March 2023DeSlChanged layout
125647view15:40, 6 March 2023DeSlConverted some arrows to specific MIM-types
125646view15:35, 6 March 2023DeSlUpdating to current color scheme
125633view02:01, 6 March 2023AlexanderPicoModified description
125272view15:34, 31 January 2023EgonwFixed two more references
125271view15:22, 31 January 2023EgonwFixed a reference
120570view01:00, 17 December 2021Khanspersupdated lit refs
120569view00:58, 17 December 2021Khanspersupdated lit refs
120568view00:45, 17 December 2021Khanspersfixed literature references to remove weird characters
117823view15:06, 22 May 2021EweitzModified title
106177view12:07, 16 August 2019MaintBotHMDB identifier normalization
102357view19:43, 20 December 2018Fehrhartfixed unconnected lines
102125view17:03, 1 December 2018EgonwRemoved whitespace in PubMed identifiers.
74511view05:59, 27 April 2014EgonwLast batch of PubMed ID fixes.
74501view17:12, 26 April 2014EgonwMore PubMed ID fixes.
74499view16:58, 26 April 2014EgonwFixed PubMed IDs.
73767view00:49, 22 February 2014MaintBotupdating schema
49735view09:04, 25 July 2012AndraRDF Tidy
49638view10:31, 23 July 2012AndraRDF Tidy
49633view09:57, 23 July 2012AndraRDF Tidy
49625view09:24, 23 July 2012AndraRDF Tidy
49624view09:22, 23 July 2012AndraRDF Tidy
49621view08:51, 23 July 2012AndraRDF Tidy
49580view07:14, 21 July 2012AndraRDF Tidy
49556view19:33, 20 July 2012AndraRDF tidy
49540view09:59, 20 July 2012AndraCorrected references
49539view09:48, 20 July 2012AndraCorrected a erroneous pubmed reference
49534view09:06, 20 July 2012AndraCorrected a pubmed error
46093view03:28, 15 December 2011AlexanderPicoconverted more hugo to hgnc
45025view18:43, 6 October 2011ThomasOntology Term : 'serotonin signaling pathway' added !
41105view23:22, 1 March 2011MaintBotRemoved redundant pathway information and comments
39767view07:54, 17 January 2011AlexanderPico
34469view18:32, 10 December 2009MaintBotAutomatic update of empty xrefs
33424view14:53, 30 November 2009MaintBotRemoved group label
33185view17:56, 5 November 2009KhanspersModified categories
31150view04:01, 5 August 2009ArukeModified description
30189view21:58, 8 July 2009ArukePeriodical save, work in progress
30183view04:17, 8 July 2009ArukePeriodical save, work in progress
30177view18:15, 7 July 2009ArukeAdded legend
30176view18:05, 7 July 2009ArukePeriodical save, work in progress
30071view18:39, 30 June 2009ArukeSpecify description
30070view18:37, 30 June 2009ArukePeriodical save, work in progress
30069view18:34, 30 June 2009ArukeSpecify description

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1,2-DiacetinMetabolite102-62-5 (CAS) diacylglycerol
1,4,5-Insp3Metabolite85166-31-0 (CAS)
BRAFGeneProduct673 (Entrez Gene) v-raf murine sarcoma viral oncogene homolog B1
CALCIUMMetabolite7440-70-2 (CAS)
CREB1GeneProduct1385 (Entrez Gene) cAMP response element-binding protein 1
ELK1GeneProduct2002 (Entrez Gene) ELK1, member of ETS oncogene family
ELK4GeneProduct2005 (Entrez Gene) ETS domain-containing protein Elk-4 (SRF accessory protein 1)
FOSGeneProduct2353 (Entrez Gene) proto-oncogene protein c-fos
GNAI1Protein2770 (Entrez Gene)
GNAI2Protein2771 (Entrez Gene)
GNAI3Protein2773 (Entrez Gene)
GNAO1Protein2775 (Entrez Gene)
Gb/gComplex
HTR1AProtein3350 (Entrez Gene)
HTR1BProtein3351 (Entrez Gene)
HTR1DProtein3352 (Entrez Gene)
HTR1EProtein3354 (Entrez Gene)
HTR1FProtein3355 (Entrez Gene)
ITPR1GeneProduct3708 (Entrez Gene) inositol 1,4,5-triphosphate receptor 1
MAP2K1GeneProduct5604 (Entrez Gene) mitogen activated protein kinase kinase 1
MAP2K2GeneProduct5605 (Entrez Gene) mitogen activated protein kinase kinase 2
MAP2K3GeneProduct5606 (Entrez Gene) mitogen activated protein kinase kinase 3
MAP2K6GeneProduct5608 (Entrez Gene) mitogen activated protein kinase kinase 6
MAP3K1GeneProduct4214 (Entrez Gene) mitogen activated protein kinase kinase kinase 1
MAPK14GeneProduct1432 (Entrez Gene) mitogen activated protein kinase 14
MAPK1GeneProductMAPK1 (HGNC) mitogen activated protein kinase 1
MAPK3GeneProduct5595 (Entrez Gene) mitogen activated protein kinase 3
MAPKAPK2GeneProduct9261 (Entrez Gene) mitogen activated protein kinase 3
MAPKAPK3GeneProduct7867 (Entrez Gene) mitogen-activated protein kinase-activated protein kinase 3
PDPK1GeneProduct5170 (Entrez Gene) 3-phosphoinositide dependent protein kinase-1
PI3KGeneProduct5290 (Entrez Gene) phosphatidylinositol 3-kinase
PKCGeneProduct50818 (Entrez Gene) protein kinase C
PLCGeneProductphospholipase C
PtdIns3PGeneProductphosphatidylinositol 3,4,5-triphosphate
RAP1AGeneProduct5906 (Entrez Gene) RAS-related protein-1a
RASGRF1GeneProduct5923 (Entrez Gene) RAS protein-specific guanine nucleotide-releasing factor 1
RASGRP1GeneProduct10125 (Entrez Gene) RAS guanyl releasing protein 1
RHOAGeneProduct387 (Entrez Gene) ras homolog gene family, member A
RPS6KGeneProductFunctional Class RPS6K (ribosomal protein S6 kinase)
RPS6KA5GeneProduct9252 (Entrez Gene) ribosomal protein S6 kinase, polypeptide 5
RasGeneProductRAS oncogene homolog
SRFGeneProduct6722 (Entrez Gene) serum response factor
SerotoninMetaboliteHMDB0000259 (HMDB)

Annotated Interactions

No annotated interactions

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