Purine metabolism (Homo sapiens)
From WikiPathways
Description
Overview of purine metabolism; metabolic markers are highlighted in red, with graphical arrows indicating if a marker is present in higher or lower concentrations compared to normal (healthy) levels.
This pathway was inspired by Chapter 13, edition 5 of the book of Blau (in press).
Proteins on this pathway have targeted assays available via the CPTAC Assay PortalQuality Tags
Ontology Terms
Saving...Bibliography
- Su, H, Lenardo, M.; ''Chapter 5 Combined Immune Deficiencies''; https://doi.org/10.1016/B978-0-12-405546-9.00005-4, 2014 DOI Scholia
- Blau, N., Duran, M., Gibson, K.M., Dionisi-Vici, C.; ''Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases, Chapter 11 and 41''; ISBN 978-3-642-40337-8, 2014
History
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External references
DataNodes
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Annotated Interactions
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| Source | Target | Type | Database reference | Comment |
|---|---|---|---|---|
| 2'-Deoxyadenosine | 2'-deoxyinosine | mim-conversion | 28191 (Rhea)  | |
| 2'-Deoxyadenosine | Adenine | mim-conversion | 27743 (Rhea) | |
| 2'-deoxyinosine | Hypoxanthine | mim-conversion | 27751 (Rhea) | |
| 2-Deoxyguanosine | Guanine | mim-conversion | 27739 (Rhea) | |
| 2-Deoxyguanosine | dGMP | mim-conversion | 19202 (Rhea) | |
| 2-Deoxyguanosine | mim-conversion | 19203 (Rhea) | ||
| ADP | ATP | mim-conversion | 30657 (Rhea) | |
| ADP | dADP | mim-conversion | 28036 (Rhea) | |
| AICARP | FAICARP | mim-conversion | 22193 (Rhea) | |
| AMP | ADP | mim-conversion | 11462 (Rhea) | |
| AMP | Adenosine | mim-conversion | 29376 (Rhea) | |
| AMP | IMP | mim-conversion | 14778 (Rhea) | |
| Adenine | AMP | mim-conversion | 16611 (Rhea) | |
| Adenosine | Adenine | mim-conversion | 18670 (Rhea) | |
| Adenosine | Inosine | mim-conversion | 24409 (Rhea) | |
| FAICARP | IMP | mim-conversion | 18447 (Rhea) | |
| GDP | GTP | mim-conversion | 29865 (Rhea) | |
| GDP | dGDP | mim-conversion | 28032 (Rhea) | |
| GMP | GDP | mim-conversion | 20781 (Rhea) | |
| GMP | Guanosine | mim-conversion | 27715 (Rhea) | |
| Guanine | mim-conversion | 14666 (Rhea) | ||
| Guanine | mim-conversion | 25426 (Rhea) | ||
| Guanosine | Guanine | mim-conversion | 13234 (Rhea) | |
| Hypoxanthine | Xanthine | mim-conversion | 24671 (Rhea) | |
| Hypoxanthine | mim-conversion | 17975 (Rhea) | ||
| IMP | Inosine | mim-conversion | 27719 (Rhea) | |
| IMP | S-AMP | mim-conversion | 15754 (Rhea) | |
| IMP | XMP | mim-conversion | 11709 (Rhea) | |
| ITP | IMP | mim-conversion | 29400 (Rhea) | |
| Inosine | Hypoxanthine | mim-conversion | 16658 (Rhea) | |
| S-AMP | AMP | mim-conversion | 16854 (Rhea) | |
| SAICARP | AICARP | mim-conversion | 23921 (Rhea) | |
| XMP | GMP | mim-conversion | 18302 (Rhea) | |
| XMP | Xanthosine | mim-conversion | 28531 (Rhea) | |
| Xanthine | Urate | mim-conversion | 16670 (Rhea) | |
| Xanthosine | Xanthine | mim-conversion | 27639 (Rhea) | |
| dADP | dAMP | mim-conversion | 23102 (Rhea) | |
| dADP | dATP | mim-conversion | 27675 (Rhea) | |
| dAMP | 2'-Deoxyadenosine | mim-conversion | 29372 (Rhea) | |
| dGDP | dGMP | mim-conversion | 12699 (Rhea) | |
| dGDP | dGTP | mim-conversion | 27691 (Rhea) |
