Focal adhesion: PI3K-Akt-mTOR-signaling (Homo sapiens)

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NOS2P1-17NOS3PCytokineNuclear to Cytoplasm TranslocationECM-Receptor InteractionsIntegrin beta (ITGB)+pIntegrin alpha (ITGA)+pVEGF Siganling/AngiogenesisCytokineRPIP3ITGA5TSC1LOC235580PIK3CACSF3GRB2JAK3JAK2EPOCOL4A2CHADITGB7TNRSTK11COL11A2LAMB3IFNA7CSH1COMPITGAECOL1A2ITGB4FN1ITGAXITGADTHBS2IL3RAPIK3R1COL5A1AKT1RELNPTK2PIK3IP1LAMC3IL2RBIFNA7LAMC2IFNAR1LAMB1NOITGA7ITGB6ITGA2BITGA9ITGA2ITGB2PIK3R2COL4A6PELOOSMRDDIT4ITGA3TNCCOL5A2LAMA4ITGA8COL4A1LAMA3LAMC1LAMB2THBS4COL2A1JAK1PIK3CBTHBS3ITGA10ITGAVPRLRIL7RITGA6LAMA5IL6RITGB1IBSPInsulinItgamCOL6A2VWFTNXBITGB5TNNSPP1PTENLAMA2CSF3RIL2RAEPORCOL3A1ITGALIL4RLAMA1SOS1ITGB3TSC2PIK3CDITGB8VTNTHBS1AKT3COL1A1COL11A1PIK3R4COL5A3IL2RGIFNA7IFNAR2COL4A4AKT2ITGA4GHRITGA11PIK3R5EFNA1FGF1FGF11FGF10EFNA2EGFFGF12CSF1ANGPT4ANGPT2ANGPT1VEGFAEFNA3EFNA4EFNA5FGF14FGF13FGF19FGF17FGF18FGF2FGF3FGF4FGF6FGF7FGF8FGF9VEGFDHGFIGF1INSINSKITLGKik1b4Kik1b4VEGFCVEGFBPDGFBPGFPDGFANGFPDGFCFGF21Fgf23FGF22PDGFDFGF20FGF16Growth FactorFGFR2KDRINSRFGFR3IGF1RKITFGFR1EPHA2EGFRCSF1RFGFR4FLT1FLT4NGFRMETPDGFRAPDGFRBTEKRTKAKT1S1PIFNA7IFNA7IFNA7IFNA7IFNA7IFNA7IFNB1IL2OSMPRLIFNA7Gm12597Ifna12IFNA7MAPK Signaling PathwayCHRM1LPAR1F2RCHRM2LPAR5LPAR2LPAR3LPAR6LPAR4GPCRGNG5GNB2GNB1Gm5741GNB4GNGT1GNG10GNG12GNB3GByGNG2GNG3GNG4GNG5GNG7GNG8GNGT2GNG13GNG11PIK3CGNRASKRASHRASChemokines, Homones, NeurotransmittersPI3K (class IA)PI3K (class IB)HypoxiaEnergy StressSTRADACAB39CAB39LPRKAA1PRKAA2MLST8RHEBMTORRPTORAMPKmTORHIF1AULK1CRTC2CDC37HSP90AB1PHLPP1TCL1APDPK1Gm2436PPP2CBPPP2CAGm2446PPP2R5DPPP2R5BPPP2R2BPPP2R1BPpp2r3dPPP2R3APPP2R5CPPP2R5EPPP2R2CPPP2R1APPP2R2DPPP2R5APPP2R3CHSP90AA1HSP90B1PHLPP2Mtcp1TCL1BTCL1BPP2ARAF1MAP2K2MAP2K1MAPK1MAPK3GSK3BPFOXO3PFOXO1PIKBKBPBADPCASP9PMDM2PIKBKGPCDKN1BPCDKN1APATF2CREB3CREB1ATF4CREB3L2CREB3L3ATF6BCREB3L1CREB3L4CREB5AMP/ATP or ADP/ATPMetforminAICAR+p+p+p+p+pTBC1D1RAB8ARAB2ARAB10RAB11BRAB14SLC2A4SLC2A1SLC2A3SLC2A2GLUTPPARGC1ADNAGYS1GYS2PFKFB2PFKFB1PFKFB3PFKFB4LIPESREBF1FOXA1ACACACell SurvivalCell CycleAutophagyCell Growth & Protein SynthesisFatty Acid BiosynthesisCholesterol synthesisGlycogen synthesisGlycolysis/GluconeogenesisCell ProliferationAngiogenesisDNA repairGlycolysis/GluconeogenesisLypolysisELAVL1NOS1P+p+p+p-p+p+p+p+p+p+pREDD1RabJAKTCL1PHLPPCREBULKPFKEPAS1HIF3ARPS6KB2EIF4EBP1EIF4BRPS6KB1RPS6EIF4EEIF4E2EIF4E1BPIK3C2BPIK3C2APik3c2gPI3K (class II)IRS1IRS4Irs3IRS2InsrIns1Ins2


Description

Cell-matrix adhesions play important roles in biological processes such as cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. Focal adhesions are structures formed at the cell-extracellular matrix contact points, consisting of bundles of actin filaments anchored to trans-membrane receptors of the integrin family through a complex of multiple proteins. In addition to participating in the structural link between membrane receptors and the actin cytoskeleton, focal adhesions also contain signaling molecules, such as protein kinases and phosphatases, their substrates, and various adapter proteins. Integrin signaling is dependent on the non-receptor tyrosine kinase activities of the FAK and src proteins and the adaptor protein functions of FAK, src and Shc to initiate downstream signaling events. These signaling events results in the reorganization of the actin cytoskeleton, which is essential for changes in cell shape and motility, and gene expression.

Source: KEGG

Proteins on this pathway have targeted assays available via the CPTAC Assay Portal

Comments

HomologyMapper 
This pathway was inferred from Mus musculus pathway "Focal Adhesion-PI3K-Akt-mTOR-signaling pathway", WP2841 revision 89989, with a 94.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

View all...
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  2. Danen EH, Yamada KM; ''Fibronectin, integrins, and growth control.''; J Cell Physiol, 2001 PubMed Europe PMC Scholia
  3. Lee JW, Juliano R; ''Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways.''; Mol Cells, 2004 PubMed Europe PMC Scholia
  4. Guo W, Giancotti FG; ''Integrin signalling during tumour progression.''; Nat Rev Mol Cell Biol, 2004 PubMed Europe PMC Scholia
  5. Comoglio PM, Boccaccio C, Trusolino L; ''Interactions between growth factor receptors and adhesion molecules: breaking the rules.''; Curr Opin Cell Biol, 2003 PubMed Europe PMC Scholia
  6. Mitra SK, Hanson DA, Schlaepfer DD; ''Focal adhesion kinase: in command and control of cell motility.''; Nat Rev Mol Cell Biol, 2005 PubMed Europe PMC Scholia
  7. Hlobilková A, Knillová J, Bártek J, Lukás J, Kolár Z; ''The mechanism of action of the tumour suppressor gene PTEN.''; Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 2003 PubMed Europe PMC Scholia
  8. Schlaepfer DD, Mitra SK; ''Multiple connections link FAK to cell motility and invasion.''; Curr Opin Genet Dev, 2004 PubMed Europe PMC Scholia
  9. Schmitz AA, Govek EE, Böttner B, Van Aelst L; ''Rho GTPases: signaling, migration, and invasion.''; Exp Cell Res, 2000 PubMed Europe PMC Scholia
  10. Berman AE, Kozlova NI, Morozevich GE; ''Integrins: structure and signaling.''; Biochemistry (Mosc), 2003 PubMed Europe PMC Scholia
  11. Stupack DG, Cheresh DA; ''Get a ligand, get a life: integrins, signaling and cell survival.''; J Cell Sci, 2002 PubMed Europe PMC Scholia
  12. Parsons JT; ''Focal adhesion kinase: the first ten years.''; J Cell Sci, 2003 PubMed Europe PMC Scholia
  13. Burridge K, Wennerberg K; ''Rho and Rac take center stage.''; Cell, 2004 PubMed Europe PMC Scholia
  14. Turner CE; ''Paxillin and focal adhesion signalling.''; Nat Cell Biol, 2000 PubMed Europe PMC Scholia
  15. Petit V, Thiery JP; ''Focal adhesions: structure and dynamics.''; Biol Cell, 2000 PubMed Europe PMC Scholia
  16. Nicholson KM, Anderson NG; ''The protein kinase B/Akt signalling pathway in human malignancy.''; Cell Signal, 2002 PubMed Europe PMC Scholia
  17. Vanhaesebroeck B, Alessi DR; ''The PI3K-PDK1 connection: more than just a road to PKB.''; Biochem J, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
135023view12:51, 31 July 2024EweitzReverted to version '11:59, 31 July 2024' by Eweitz
135016view12:04, 31 July 2024EweitzWP3945
135015view11:59, 31 July 2024EweitzAdd gene identifier, standardize case
129711view01:30, 22 May 2024EweitzModified title
128553view04:41, 12 February 2024EweitzFix typo, standardize case
124527view12:58, 4 November 2022Marvin M2Typo corrected in label
120304view15:09, 26 November 2021DeSlOntology Term : 'signaling pathway' added !
120303view15:09, 26 November 2021DeSlOntology Term : 'PW:0000003' removed !
120302view15:09, 26 November 2021DeSlOntology Term : 'cell adhesion signaling pathway' added !
120301view15:08, 26 November 2021DeSlOntology Term : 'PW:0000648' removed !
120300view15:08, 26 November 2021DeSlOntology Term : 'mTOR signaling pathway' added !
120299view15:06, 26 November 2021DeSlOntology Term : 'PW:0000180' removed !
118902view21:46, 3 June 2021EweitzModified title
118901view21:44, 3 June 2021EweitzOntology Term : 'PW:0000595' removed !
118900view21:44, 3 June 2021EweitzOntology Term : 'PW:0000003' removed !
118899view21:44, 3 June 2021EweitzOntology Term : 'PW:0000180' removed !
106555view00:28, 6 September 2019KhanspersModified description
106554view00:21, 6 September 2019KhanspersModified description
106420view22:01, 28 August 2019KhanspersModified description
105465view05:13, 8 August 2019KhanspersModified description
105463view05:12, 8 August 2019KhanspersUndo revision 105462 by [[Special:Contributions/Khanspers|Khanspers]] ([[User talk:Khanspers|Talk]])
105462view05:11, 8 August 2019KhanspersModified description
102154view19:07, 4 December 2018Khanspersupdated Z83313.1 to FGF13
94216view21:51, 25 August 2017DeSlAdded ID for insulin.
94214view21:47, 25 August 2017DeSlAdded ID for NO.
91101view01:26, 4 January 2017Khanspersconnected interactions, started updating state information
90760view01:05, 14 December 2016Khanspersupdated source pathway information
90759view01:05, 14 December 2016KhanspersOntology Term : 'phosphatidylinositol 3-kinase signaling pathway' added !
90758view01:04, 14 December 2016KhanspersOntology Term : 'signaling pathway' added !
90757view01:04, 14 December 2016KhanspersOntology Term : 'mTOR signaling pathway' added !
90756view01:02, 14 December 2016KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACACAGeneProductENSG00000278540 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:107476
AKT1GeneProductENSG00000142208 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11651
AKT1S1GeneProductENSG00000204673 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67605
AKT2GeneProductENSG00000105221 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11652
AKT3GeneProductENSG00000117020 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:23797
ANGPT1GeneProductENSG00000154188 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11600
ANGPT2GeneProductENSG00000091879 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11601
ANGPT4GeneProductENSG00000101280 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11602
ATF2GeneProductENSG00000115966 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11909
ATF4GeneProductENSG00000128272 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11911
ATF6BGeneProductENSG00000213676 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12915
BADGeneProductENSG00000002330 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12015
CAB39GeneProductENSG00000135932 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12283
CAB39LGeneProductENSG00000102547 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:69008
CASP9GeneProductENSG00000132906 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12371
CDC37GeneProductENSG00000105401 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12539
CDKN1AGeneProductENSG00000124762 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12575
CDKN1BGeneProductENSG00000111276 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12576
CHADGeneProductENSG00000136457 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12643
CHRM1GeneProductENSG00000168539 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12669
CHRM2GeneProductENSG00000181072 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:243764
COL11A1GeneProductENSG00000060718 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12814
COL11A2GeneProductENSG00000204248 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12815
COL1A1GeneProductENSG00000108821 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12842
COL1A2GeneProductENSG00000164692 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12843
COL2A1GeneProductENSG00000139219 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12824
COL3A1GeneProductENSG00000168542 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12825
COL4A1GeneProductENSG00000187498 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12826
COL4A2GeneProductENSG00000134871 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12827
COL4A4GeneProductENSG00000081052 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12829
COL4A6GeneProductENSG00000197565 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:94216
COL5A1GeneProductENSG00000130635 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12831
COL5A2GeneProductENSG00000204262 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12832
COL5A3GeneProductENSG00000080573 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867
COL6A2GeneProductENSG00000142173 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12834
COMPGeneProductENSG00000105664 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12845
CREB1GeneProductENSG00000118260 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12912
CREB3GeneProductENSG00000107175 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12913
CREB3L1GeneProductENSG00000157613 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26427
CREB3L2GeneProductENSG00000182158 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208647
CREB3L3GeneProductENSG00000060566 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208677
CREB3L4GeneProductENSG00000143578 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:78284
CREB5GeneProductENSG00000146592 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:231991
CRTC2GeneProductENSG00000160741 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74343
CSF1GeneProductENSG00000184371 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12977
CSF1RGeneProductENSG00000182578 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12978
CSF3GeneProductENSG00000108342 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12985
CSF3RGeneProductENSG00000119535 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986
CSH1GeneProductENSG00000136488 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14599
DDIT4GeneProductENSG00000168209 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747
EFNA1GeneProductENSG00000169242 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13636
EFNA2GeneProductENSG00000099617 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13637
EFNA3GeneProductENSG00000143590 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13638
EFNA4GeneProductENSG00000243364 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13639
EFNA5GeneProductENSG00000184349 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13640
EGFGeneProductENSG00000138798 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13645
EGFRGeneProductENSG00000146648 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13649
EIF4BGeneProductENSG00000063046 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75705
EIF4E1BGeneProductENSG00000175766 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:218268
EIF4E2GeneProductENSG00000135930 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26987
EIF4EBP1GeneProductENSG00000187840 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13685
EIF4EGeneProductENSG00000151247 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13684
ELAVL1GeneProductENSG00000066044 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15568
EPAS1GeneProductENSG00000116016 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13819
EPHA2GeneProductENSG00000142627 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13836
EPOGeneProductENSG00000130427 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13856
EPORGeneProductENSG00000187266 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13857
F2RGeneProductENSG00000181104 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14062
FGF10GeneProductENSG00000070193 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14165
FGF11GeneProductENSG00000161958 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14166
FGF12GeneProductENSG00000114279 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14167
FGF13GeneProductENSG00000129682 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14168
FGF14GeneProductENSG00000102466 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14169
FGF16GeneProductENSG00000196468 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80903
FGF17GeneProductENSG00000158815 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14171
FGF18GeneProductENSG00000156427 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14172
FGF19GeneProductENSG00000162344 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14170
FGF1GeneProductENSG00000113578 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14164
FGF20GeneProductENSG00000078579 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80857
FGF21GeneProductENSG00000105550 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56636
FGF22GeneProductENSG00000070388 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67112
FGF2GeneProductENSG00000138685 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14173
FGF3GeneProductENSG00000186895 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14174
FGF4GeneProductENSG00000075388 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14175
FGF6GeneProductENSG00000111241 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14177
FGF7GeneProductENSG00000140285 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14178
FGF8GeneProductENSG00000107831 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14179
FGF9GeneProductENSG00000102678 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14180
FGFR1GeneProductENSG00000077782 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14182
FGFR2GeneProductENSG00000066468 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14183
FGFR3GeneProductENSG00000068078 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14184
FGFR4GeneProductENSG00000160867 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14186
FLT1GeneProductENSG00000102755 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14254
FLT4GeneProductENSG00000037280 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14257
FN1GeneProductENSG00000115414 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14268
FOXA1GeneProductENSG00000129514 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15375
FOXO1GeneProductENSG00000150907 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56458
FOXO3GeneProductENSG00000118689 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56484
Fgf23GeneProduct
GHRGeneProductENSG00000112964 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14600
GNB1GeneProductENSG00000078369 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14688
GNB2GeneProductENSG00000172354 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14693
GNB3GeneProductENSG00000111664 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14695
GNB4GeneProductENSG00000114450 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14696
GNG10GeneProductENSG00000242616 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14700
GNG11GeneProductENSG00000127920 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:66066
GNG12GeneProductENSG00000172380 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14701
GNG13GeneProductENSG00000127588 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:64337
GNG2GeneProductENSG00000186469 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14702
GNG3GeneProductENSG00000162188 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14704
GNG4GeneProductENSG00000168243 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14706
GNG5GeneProductENSG00000174021 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14707
GNG7GeneProductENSG00000176533 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14708
GNG8GeneProductENSG00000167414 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14709
GNGT1GeneProductENSG00000127928 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14699
GNGT2GeneProductENSG00000167083 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14710
GRB2GeneProductENSG00000177885 (Ensembl)
  • GRB2; growth factor receptor-bound protein 2
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14784
GSK3BGeneProductENSG00000082701 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56637
GYS1GeneProductENSG00000104812 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14936
GYS2GeneProductENSG00000111713 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:232493
Gm12597GeneProduct
Gm2436GeneProduct
Gm2446GeneProduct
Gm5741GeneProductNo homologues found for original id L:100503710
HGFGeneProductENSG00000019991 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15234
HIF1AGeneProductENSG00000100644 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15251
HIF3AGeneProductENSG00000124440 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53417
HRASGeneProductENSG00000174775 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15461
HSP90AA1GeneProductENSG00000080824 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15519
HSP90AB1GeneProductENSG00000096384 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15516
HSP90B1GeneProductENSG00000166598 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22027
IBSPGeneProductENSG00000029559 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15891
IFNA7GeneProductENSG00000214042 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:404549
IFNAR1GeneProductENSG00000142166 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15975
IFNAR2GeneProductENSG00000159110 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15976
IFNB1GeneProductENSG00000171855 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15977
IGF1GeneProductENSG00000017427 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16000
IGF1RGeneProductENSG00000140443 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16001
IKBKBGeneProductENSG00000104365 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16150
IKBKGGeneProductENSG00000269335 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16151
IL2GeneProductENSG00000109471 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183
IL2RAGeneProductENSG00000134460 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16184
IL2RBGeneProductENSG00000100385 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16185
IL2RGGeneProductENSG00000147168 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16186
IL3RAGeneProductENSG00000185291 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16188
IL4RGeneProductENSG00000077238 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16190
IL6RGeneProductENSG00000160712 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16194
IL7RGeneProductENSG00000168685 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16197
INSGeneProductENSG00000254647 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16334
INSRGeneProductENSG00000171105 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16337
IRS1GeneProductENSG00000169047 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16367
IRS2GeneProductENSG00000185950 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:384783
IRS4GeneProductENSG00000133124 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16370
ITGA10GeneProductENSG00000143127 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000090210
ITGA11GeneProductENSG00000137809 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:319480
ITGA2BGeneProductENSG00000005961 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16399
ITGA2GeneProductENSG00000164171 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16398
ITGA3GeneProductENSG00000005884 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16400
ITGA4GeneProductENSG00000115232 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16401
ITGA5GeneProductENSG00000161638 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16402
ITGA6GeneProductENSG00000091409 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16403
ITGA7GeneProductENSG00000135424 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16404
ITGA8GeneProductENSG00000077943 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:241226
ITGA9GeneProductENSG00000144668 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:104099
ITGADGeneProductENSG00000156886 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:381924
ITGAEGeneProductENSG00000083457 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16407
ITGALGeneProductENSG00000005844 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16408
ITGAVGeneProductENSG00000138448 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = M:MGI:96608
ITGAXGeneProductENSG00000140678 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16411
ITGB1GeneProductENSG00000150093 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16412
ITGB2GeneProductENSG00000160255 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16414
ITGB3GeneProductENSG00000259207 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16416
ITGB4GeneProductENSG00000132470 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:192897
ITGB5GeneProductENSG00000082781 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16419
ITGB6GeneProductENSG00000115221 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16420
ITGB7GeneProductENSG00000139626 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16421
ITGB8GeneProductENSG00000105855 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320910
Ifna12GeneProduct
Ins1GeneProductGRB2; growth factor receptor-bound protein 2
Ins2GeneProductGRB2; growth factor receptor-bound protein 2
InsrGeneProductGRB2; growth factor receptor-bound protein 2
InsulinMetaboliteCHEBI:5931 (ChEBI)
Irs3GeneProductNo homologues found for original id L:16369
ItgamGeneProductMultiple homologues found: En:ENSG00000169896;En:ENSG00000169896;
JAK1GeneProductENSG00000162434 (Ensembl)
  • CAV1; caveolin 1 caveolae protein 22kD
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16451
JAK2GeneProductENSG00000096968 (Ensembl)
  • CAV2; caveolin 2
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16452
JAK3GeneProductENSG00000105639 (Ensembl)
  • CAV3; caveolin 3
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16453
KDRGeneProductENSG00000128052 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16542
KITGeneProductENSG00000157404 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16590
KITLGGeneProductENSG00000049130 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17311
KRASGeneProductENSG00000133703 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16653
Kik1b4GeneProduct
LAMA1GeneProductENSG00000101680 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16772
LAMA2GeneProductENSG00000196569 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16773
LAMA3GeneProductENSG00000053747 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000024421
LAMA4GeneProductENSG00000112769 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16775
LAMA5GeneProductENSG00000130702 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16776
LAMB1GeneProductENSG00000091136 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16777
LAMB2GeneProductENSG00000172037 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16779
LAMB3GeneProductENSG00000196878 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16780
LAMC1GeneProductENSG00000135862 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:226519
LAMC2GeneProductENSG00000058085 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16782
LAMC3GeneProductENSG00000050555 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:23928
LIPEGeneProductENSG00000079435 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16890
LOC235580GeneProduct
LPAR1GeneProductENSG00000198121 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14745
LPAR2GeneProductENSG00000064547 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53978
LPAR3GeneProductENSG00000171517 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:65086
LPAR4GeneProductENSG00000147145 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:78134
LPAR5GeneProductENSG00000184574 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:381810
LPAR6GeneProductENSG00000139679 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67168
MAP2K1GeneProductENSG00000169032 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26395
MAP2K2GeneProductENSG00000126934 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26396
MAPK1GeneProductENSG00000100030 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26413
MAPK3GeneProductENSG00000102882 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26417
MDM2GeneProductENSG00000135679 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246
METGeneProductENSG00000105976 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17295
MLST8GeneProductENSG00000167965 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56716
MTORGeneProductENSG00000198793 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56717
Mtcp1GeneProductMultiple homologues found: En:ENSG00000214827;En:ENSG00000182712;
NGFGeneProductENSG00000134259 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18049
NGFRGeneProductENSG00000064300 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18053
NOMetaboliteCHEBI:29120 (ChEBI) Added ID for Nitric oxide (1+), which makes more sense then NO(radical)
NOS1GeneProductENSG00000089250 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18125
NOS2GeneProductENSG00000007171 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18126
NOS3GeneProductENSG00000164867 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18127
NRASGeneProductENSG00000213281 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18176
OSMGeneProductENSG00000099985 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18413
OSMRGeneProductENSG00000145623 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18414
PDGFAGeneProductENSG00000197461 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18590
PDGFBGeneProductENSG00000100311 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18591
PDGFCGeneProductENSG00000145431 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:54635
PDGFDGeneProductENSG00000170962 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:71785
PDGFRAGeneProductENSG00000134853 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18595
PDGFRBGeneProductENSG00000113721 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18596
PDPK1GeneProductENSG00000140992 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18607
PELOGeneProductENSG00000152684 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:105083
PFKFB1GeneProductENSG00000158571 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18639
PFKFB2GeneProductENSG00000123836 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18640
PFKFB3GeneProductENSG00000170525 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:170768
PFKFB4GeneProductENSG00000114268 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:270198
PGFGeneProductENSG00000119630 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18654
PHLPP1GeneProductENSG00000081913 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:98432
PHLPP2GeneProductENSG00000040199 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:244650
PIK3C2AGeneProductENSG00000011405 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18704
PIK3C2BGeneProductENSG00000133056 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:240752
PIK3CAGeneProductENSG00000121879 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18706
PIK3CBGeneProductENSG00000051382 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74769
PIK3CDGeneProductENSG00000171608 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18707
PIK3CGGeneProductENSG00000105851 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:30955
PIK3IP1GeneProductENSG00000100100 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:216505
PIK3R1GeneProductENSG00000145675 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18708
PIK3R2GeneProductENSG00000105647 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18709
PIK3R4GeneProductENSG00000196455 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75669
PIK3R5GeneProductENSG00000141506 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320207
PPARGC1AGeneProductENSG00000109819 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19017
PPP2CAGeneProductENSG00000113575 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19052
PPP2CBGeneProductENSG00000104695 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19053
PPP2R1AGeneProductENSG00000105568 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:51792
PPP2R1BGeneProductENSG00000137713 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:73699
PPP2R2BGeneProductENSG00000156475 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72930
PPP2R2CGeneProductENSG00000074211 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:269643
PPP2R2DGeneProductENSG00000175470 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:52432
PPP2R3AGeneProductENSG00000073711 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:235542
PPP2R3CGeneProductENSG00000092020 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:59032
PPP2R5AGeneProductENSG00000066027 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:226849
PPP2R5BGeneProductENSG00000068971 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:225849
PPP2R5CGeneProductENSG00000078304 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26931
PPP2R5DGeneProductENSG00000112640 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21770
PPP2R5EGeneProductENSG00000154001 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26932
PRKAA1GeneProductENSG00000132356 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:105787
PRKAA2GeneProductENSG00000162409 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:108079
PRLGeneProductENSG00000172179 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19109
PRLRGeneProductENSG00000113494 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19116
PTENGeneProductENSG00000171862 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19211
PTK2GeneProductENSG00000169398 (Ensembl)
  • DOCK1; dedicator of cyto-kinesis
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14083
Pik3c2gGeneProductNo homologues found for original id L:18705
Ppp2r3dGeneProduct
RAB10GeneProductENSG00000084733 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19325
RAB11BGeneProductENSG00000185236 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19326
RAB14GeneProductENSG00000119396 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:68365
RAB2AGeneProductENSG00000104388 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:59021
RAB8AGeneProductENSG00000167461 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17274
RAF1GeneProductENSG00000132155 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:110157
RELNGeneProductENSG00000189056 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19699
RHEBGeneProductENSG00000106615 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19744
RPS6GeneProductENSG00000137154 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20104
RPS6KB1GeneProductENSG00000108443 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72508
RPS6KB2GeneProductENSG00000175634 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:58988
RPTORGeneProductENSG00000141564 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74370
SLC2A1GeneProductENSG00000117394 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20525
SLC2A2GeneProductENSG00000163581 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20526
SLC2A3GeneProductENSG00000059804 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20527
SLC2A4GeneProductENSG00000181856 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20528
SOS1GeneProductENSG00000115904 (Ensembl)
  • SOS1; son of sevenless homolog 1 (Drosophila)
  • Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20662
SPP1GeneProductENSG00000118785 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20750
SREBF1GeneProductENSG00000072310 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20787
STK11GeneProductENSG00000118046 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20869
STRADAGeneProductENSG00000266173 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72149
TBC1D1GeneProductENSG00000065882 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:57915
TCL1AGeneProductENSG00000100721 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21432
TCL1BGeneProductENSG00000213231 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:27380
TEKGeneProductENSG00000120156 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21687
THBS1GeneProductENSG00000137801 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21825
THBS2GeneProductENSG00000186340 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21826
THBS3GeneProductENSG00000169231 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21827
THBS4GeneProductENSG00000113296 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21828
TNCGeneProductENSG00000041982 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21923
TNNGeneProductENSG00000120332 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:329278
TNRGeneProductENSG00000116147 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21960
TNXBGeneProductENSG00000168477 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:81877
TSC1GeneProductENSG00000165699 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:64930
TSC2GeneProductENSG00000103197 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22084
ULK1GeneProductENSG00000177169 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22241
VEGFAGeneProductENSG00000112715 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22339
VEGFBGeneProductENSG00000173511 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22340
VEGFCGeneProductENSG00000150630 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22341
VEGFDGeneProductENSG00000165197 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14205
VTNGeneProductENSG00000109072 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22370
VWFGeneProductENSG00000110799 (Ensembl) Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22371

Annotated Interactions

No annotated interactions
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