Methylerythritol phosphate pathway (Oryza sativa)

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NADPH2-C-methyl-D-erythritol-4-phosphateLOC_Os06g05100EC:1.1.1.267NADP+LOC_Os07g36190LOC_Os02g39160pyruvate1-deoxy-D-xylulose 5-phosphateCMPEC:2.2.1.7LOC_Os05g33840ATPdimethylallyl-PPLOC_Os02g45660H2OLOC_Os05g34180Δ3-isopentenyl-PPADPCO2protein disulfidepolyisoprenoid biosynthesisLOC_Os01g66360diphosphate4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritolEC:5.3.3.21-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphateLOC_Os07g09190D-glyceraldehyde-3-phosphate2-C-methyl-D-erythritol-2,4-cyclodiphosphateLOC_Os01g58790phytyl-PP biosynthesisLOC_Os03g52170geranylgeranyldiphosphate biosynthesis II (plastidic)EC:2.7.7.60protein dithiolLOC_Os01g01710EC:1.17.1.2EC:2.7.1.148EC:1.17.4.3EC:4.6.1.12LOC_Os07g40260CTP2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritolNAD(P)+NAD(P)HH2OH+


Description

In plants, the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway located in the plastids provides precursors for the isoprenoid hormones, monoterpenes, carotenoids and chlorophyll side chains, prenylquinones and tocopherol biosynthesis.

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Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
123064view04:00, 23 June 2022EgonwMade a pathway clickable
98196view10:19, 5 August 2018EgonwReplaced the CAS number of a salt with that of the parent compound.
94568view06:49, 28 September 2017DeSlAnnotated metabolite node; changed 2 metabolite nodes to proteins, changed ID for NAD(P)H to correct one.
89689view10:07, 26 September 2016EgonwReplace the CAS number of the salt with that of just the metabolite.
86878view07:46, 14 July 2016MkutmonOntology Term : 'tetrahydrobiopterin metabolic pathway' added !
86877view07:46, 14 July 2016MkutmonOntology Term : 'PW:0000217' removed !
71857view20:33, 18 October 2013EgonwFixed the KEGG Compound database name.
70139view20:57, 12 July 2013MaintBotupdated to 2013 schema
57085view20:43, 20 January 2013EgonwAdded missing CAS data source.
48985view22:51, 2 July 2012PjaiswalModified categories
48635view22:06, 7 June 2012PjaiswalModified description
48634view22:02, 7 June 2012PjaiswalOntology Term : 'plant cell' added !
48633view22:02, 7 June 2012PjaiswalOntology Term : 'metabolic pathway of prosthetic groups, electron carriers and reductants' added !
48632view22:00, 7 June 2012Pjaiswaladded xref to EC:1.17.4.3
48630view21:42, 7 June 2012PjaiswalNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1-deoxy-D-xylulose 5-phosphateMetaboliteC11437 (Kegg Compound)
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphateMetaboliteC11811 (Kegg Compound)
2-C-methyl-D-erythritol-2,4-cyclodiphosphateMetaboliteC11453 (Kegg Compound)
2-C-methyl-D-erythritol-4-phosphateMetaboliteC11434 (Kegg Compound)
2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritolMetabolite
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritolMetaboliteC11435 (Kegg Compound)
ADPMetabolite58-64-0 (CAS)
ATPMetabolite56-65-5 (CAS)
CMPMetabolite63-37-6 (CAS)
CO2Metabolite124-38-9 (CAS)
CTPMetabolite65-47-4 (CAS)
D-glyceraldehyde-3-phosphateMetabolite142-10-9 (CAS)
EC:1.1.1.267GeneProduct1.1.1.267 (EC Number)
EC:1.17.1.2GeneProduct1.17.1.2 (EC Number)
EC:1.17.4.3GeneProduct1.17.4.3 (EC Number)
EC:2.2.1.7GeneProduct2.2.1.7 (EC Number)
EC:2.7.1.148GeneProduct2.7.1.148 (EC Number)
EC:2.7.7.60GeneProduct2.7.7.60 (EC Number)
EC:4.6.1.12GeneProduct4.6.1.12 (EC Number)
EC:5.3.3.2GeneProduct5.3.3.2 (EC Number)
H+Metabolite12408-02-5 (CAS)
H2OMetabolite7732-18-5 (CAS)
LOC_Os01g01710GeneProductLOC_Os01g01710 (Gramene Rice) 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplast precursor, putative, expressed//isoprenoid biosynthetic process//catalytic activity//1-deoxy-D-xylulose-5-phosphate reductoisomerase
LOC_Os01g58790GeneProductLOC_Os01g58790 (Gramene Rice) GHMP kinases ATP-binding protein, putative, expressed//ATP binding//terpenoid biosynthetic process//4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
LOC_Os01g66360GeneProductLOC_Os01g66360 (Gramene Rice) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, putative, expressed//terpenoid biosynthetic process//4-diphosphocytidyl-2C-methyl-D-erythritol synthase
LOC_Os02g39160GeneProductLOC_Os02g39160 (Gramene Rice) hydroxymethylbutenyl 4-diphosphate synthase, putative, expressed//terpenoid biosynthetic process//sugar:hydrogen symporter activity//phosphoenolpyruvate-dependent sugar phosphotransferase system//4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
LOC_Os02g45660GeneProductLOC_Os02g45660 (Gramene Rice) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplast precursor, putative, expressed//terpenoid biosynthetic process//2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
LOC_Os03g52170GeneProductLOC_Os03g52170 (Gramene Rice) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, putative, expressed//terpenoid biosynthetic process
LOC_Os05g33840GeneProductLOC_Os05g33840 (Gramene Rice) transketolase, putative, expressed//terpenoid biosynthetic process//1-deoxy-D-xylulose-5-phosphate synthase//transketolase
LOC_Os05g34180GeneProductLOC_Os05g34180 (Gramene Rice) hydrolase, NUDIX family, domain containing protein, expressed//isoprenoid biosynthetic process//terpenoid biosynthetic process//isopentenyl-diphosphate delta-isomerase
LOC_Os06g05100GeneProductLOC_Os06g05100 (Gramene Rice) transketolase, putative, expressed//terpenoid biosynthetic process//1-deoxy-D-xylulose-5-phosphate synthase
LOC_Os07g09190GeneProductLOC_Os07g09190 (Gramene Rice) transketolase, putative, expressed//terpenoid biosynthetic process
LOC_Os07g36190GeneProductLOC_Os07g36190 (Gramene Rice) hydrolase, NUDIX family, domain containing protein, expressed//isopentenyl-diphosphate delta-isomerase
LOC_Os07g40260GeneProductLOC_Os07g40260 (Gramene Rice) eukaryotic aspartyl protease domain containing protein, expressed
NAD(P)+Metabolite53-59-8 (CAS)
NAD(P)HMetabolite2646-71-1 (CAS)
NADP+Metabolite53-59-8 (CAS)
NADPHMetabolite2646-71-1 (CAS)
dimethylallyl-PPMetabolite358-71-4 (CAS)
diphosphateMetabolite2466-09-3 (CAS)
geranylgeranyldiphosphate biosynthesis II (plastidic)PathwayWP2211 (WikiPathways)
phytyl-PP biosynthesisPathway
polyisoprenoid biosynthesisPathway
protein disulfideMetabolite
protein dithiolMetabolite
pyruvateMetabolite127-17-3 (CAS)
Δ3-isopentenyl-PPMetaboliteC00129 (Kegg Compound)

Annotated Interactions

No annotated interactions

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