Common pathways underlying drug addiction (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Li CY, Mao X, Wei L; ''Genes and (common) pathways underlying drug addiction.''; PLoS Comput Biol, 2008 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	129835	view	00:39, 23 May 2024	Eweitz	Link to WP pathway, refine clickability affordance, standardize case
	116781	view	09:52, 14 May 2021	Eweitz	Modified title
	106363	view	23:03, 22 August 2019	Khanspers	Modified description
	105556	view	06:15, 9 August 2019	Khanspers	Modified description
	95595	view	14:20, 5 January 2018	DeSl	Found incorrect identifier for glutamate (was the same as dopamine).
	89423	view	22:39, 10 September 2016	AlexanderPico	added missing interactions and red/blue highlighted cycles
	89422	view	22:36, 10 September 2016	AlexanderPico	Ontology Term : 'alcohol dependence' added !
	89421	view	22:35, 10 September 2016	AlexanderPico	Ontology Term : 'nicotine addiction pathway' added !
	89420	view	22:35, 10 September 2016	AlexanderPico	Ontology Term : 'morphine addiction pathway' added !
	89419	view	22:33, 10 September 2016	AlexanderPico	Ontology Term : 'cocaine addiction pathway' added !
	89418	view	22:33, 10 September 2016	AlexanderPico	Ontology Term : 'amphetamine addiction pathway' added !
	89417	view	22:31, 10 September 2016	AlexanderPico	Modified description
	89416	view	22:19, 10 September 2016	AlexanderPico	finished adding xrefs and complexes
	89415	view	22:07, 10 September 2016	AlexanderPico	More xrefs and complexes added
	89414	view	21:37, 10 September 2016	AlexanderPico	Updated complexes and translation processes; additional layout changes
	89413	view	21:12, 10 September 2016	AlexanderPico	updated layout and labels; added Actin
	89374	view	06:24, 10 September 2016	Egonw	Widened label so that the full text is visible.
	89373	view	06:23, 10 September 2016	Egonw	Connected lines.
	87531	view	02:03, 25 July 2016	AlexanderPico	Ontology Term : 'drug pathway' added !
	87530	view	02:02, 25 July 2016	AlexanderPico	Ontology Term : 'disease pathway' added !
	87529	view	02:02, 25 July 2016	AlexanderPico	Modified title
	84387	view	21:19, 18 February 2016	Khanspers	Modified description
	82194	view	09:47, 13 September 2015	Egonw	Fixed the Ensembl data source ("Ensembl Human" -> "Ensembl")
	73720	view	13:03, 19 February 2014	Andra	added identifiers
	73719	view	23:13, 18 February 2014	Andra	Modified description
	73718	view	23:08, 18 February 2014	Andra	added identifiers
	73717	view	22:50, 18 February 2014	Andra	added connections
	73716	view	22:48, 18 February 2014	Andra	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
AC1/8	GeneProduct
ADCY	GeneProduct	4.6.1.1 (Enzyme Nomenclature)
AMPAR	GeneProduct
CAMK4	GeneProduct	ENSG00000152495 (Ensembl Human)
CREB	GeneProduct
Ca++	Metabolite	266 (Chemspider)
CaM	GeneProduct
CaMKII	GeneProduct
Connexin	GeneProduct	PF00029 (Pfam)
DRD1	GeneProduct	ENSG00000184845 (Ensembl Human)
DRD2	GeneProduct	ENSG00000149295 (Ensembl Human)
DRD4	GeneProduct	ENSG00000069696 (Ensembl)
Dopamine	Metabolite	661 (Chemspider)
ERK1/2	GeneProduct
Gap Junction	Pathway
Gi	GeneProduct
Glutamate	Metabolite	661 (Chemspider)
GnRH Signal Pathway	Pathway
Gonadotropins gene expression & secretion	Pathway
Gs	GeneProduct
I-1	GeneProduct
Local translation	Pathway
MAPK Signaling pathway	Pathway
MEK1/2	GeneProduct
NMDAR	GeneProduct
Neuroactive ligand-receptor interaction	Pathway
PKA	GeneProduct	2.7.11.11 (Enzyme Nomenclature)
PKC	GeneProduct	2.7.11.13 (Enzyme Nomenclature)
PP1	GeneProduct
Raf	GeneProduct
Rap1	GeneProduct
Regulation of Gap junction	Pathway
Regulation of actin skeleton	Pathway
Strong depolarization	Pathway
cAMP	Metabolite	5851 (Chemspider)
mGluR	GeneProduct

Annotated Interactions

No annotated interactions