Poly(glycerol phosphate) wall teichoic acid biosynthesis (Saccharomyces cerevisiae)

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cytosolTransportBs-tagBUDP (n)diphosphateBs-dltA2 H+a peptidoglycan-major wall teichoic acid complexH+ (n)UDP-N-acetyl-alpha-D-mannosaminedi-trans,octa-cis-undecaprenyl phosphate an L-1-phosphatidyl-sn-glycerolUDP-alpha-D-glucose (n)ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-beta-D-glucosaminyl)-(1,4-)]-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineUDPBs-tagAH2Odi-trans,octa-cis-undecaprenyl diphosphate N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol2-O-D-alanyl-1-O-phosphatidylglycerola polyisoprenyl-major wall techoic acidBs-tagOa D-alanyl-carrier proteinCMP (n)phosphateManNAc-GlcNAc-PP-undecaprenolUDP-N-acetyl-D-glucosamine biosynthesis IATPGro-P-ManNac-GlcNAc-PP-undecaprenolsn-glycerol-3-phosphatediphosphateH+D-alanineBs-mnaAUDP-N-acety-alpha-D-glucosamideATPCDP-glycerolCDP-glycerol(n)AMPD-alanylH2Odi-trans,octa-cis-undecaprenyl phosphateUMPH+CMPH+CTPBs-tagD(Gro-P)n Gro-P-ManNac-GlcNAc-PP-undecaprenolBs-tagF((2-Glc)Gro-P)n Gro-P-ManNac-GlcNAc-PP-undecaprenolextracellular space((2-Glc)Gro-P)n Gro-P-ManNac-GlcNAc-PP-undecaprenolBs-tagEBs-tagH + Bs-tagGADPH+a D-alanyl-carrier proteinBs-dltDa D-alanyl-carrier proteinan L-1-phosphatidyl-sn-glycerolBs-dltBBs-tagV + Bs-tagU + Bs-tagT


Description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Gale, R. T., Sewell, E. W., Garrett, T. A., Brown, E. D.; ''Reconstituting poly (glycerol phosphate) wall teichoic acid biosynthesis in vitro using authentic substrates.''; Chemical Science, 2014 DOI Scholia

History

View all...
CompareRevisionActionTimeUserComment
129256view10:23, 16 March 2024EgonwOntology Term : 'classic metabolic pathway' added !
129255view10:22, 16 March 2024EgonwModified description
125299view17:33, 31 January 2023LarsgwAdd DOI to reference
124814view21:49, 11 December 2022AlexanderPicofixed citations
124783view06:38, 11 December 2022AlexanderPicofixed citations
117327view11:48, 20 May 2021EweitzModified title
107260view14:35, 17 September 2019MaintBotChEBI identifier normalization
102328view11:16, 20 December 2018EgonwReplace the identifier with that of the neutral compound.
96442view08:05, 15 March 2018EgonwReplaced secondary ChEBI identifiers with primary identifiers.
96269view05:23, 3 March 2018EgonwCorrected the data sources.
95539view10:55, 21 December 2017DeSlAdded literature reference
95538view10:50, 21 December 2017DeSlAdded missing identifier
95537view10:41, 21 December 2017DeSlConnected lines where I could, added identifiers for metabolites+reactions
95536view09:59, 21 December 2017DeSlAdded reaction ID.
95535view09:53, 21 December 2017DeSlAnnotated additional metabolites
95534view09:22, 21 December 2017DeSlAdded several IDs
95485view10:11, 18 December 2017Andraadded missing metabolite identifiers
95384view11:06, 11 December 2017DeSlAdded IDs to several metabolites.
95061view13:02, 11 November 2017EgonwFixed the data source of three Wikidata identifiers.
94983view11:44, 23 October 2017DeSlannotated some nodes
94971view14:20, 20 October 2017DeSlModified description
94970view14:19, 20 October 2017DeSlModified description
94969view14:18, 20 October 2017DeSlNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
((2-Glc)Gro-P)n Gro-P-ManNac-GlcNAc-PP-undecaprenolMetabolite
(Gro-P)n Gro-P-ManNac-GlcNAc-PP-undecaprenolMetabolite
2 H+Metabolite
2-O-D-alanyl-1-O-phosphatidylglycerolMetabolite
ADPMetabolite
AMPMetabolite
ATPMetabolite
Bs-dltAProtein6.2.1.M5 (Enzyme Nomenclature) D-alanine-[D-alanyl carrier protein] ligase (Bs)
Bs-dltBProtein2.3.1.M32 (Enzyme Nomenclature) PG: teichoic acid D-alanyltransferase (Bs)
Bs-dltDProtein2.3.1.M31 (Enzyme Nomenclature) D-alanine carrier protein:PG D-alanyltransferase (Bs)
Bs-mnaAProtein5.1.3.14 (Enzyme Nomenclature) UDP-N-acetylglucosamine 2-epimerase (BS)
Bs-tagAProtein2.4.1.187 (Enzyme Nomenclature) UDP-N-acetylmannosamine transferase (Bs)
Bs-tagBProtein2.7.8.44 (Enzyme Nomenclature) Teichoic acid glycerol-phosphate primase (Bs)
Bs-tagDProtein2.7.7.39 (Enzyme Nomenclature) glycerol-3-phosphate-cytidyltransferase (Bs)
Bs-tagEProtein2.4.1.52 (Enzyme Nomenclature) Poly(glycerol-phosphate)alpha-glucosyltranferase (Bs)
Bs-tagFProtein2.7.8.12 (Enzyme Nomenclature) Teichoic acid poly(glycerol-phosphate) polymerase (Bs)
Bs-tagH + Bs-tagGProtein3.6.3.40 (Enzyme Nomenclature) Poly(glycerol-phosphate) teichoic acid transporter (Bs)
Bs-tagOProtein2.7.8.33 (Enzyme Nomenclature) UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase (Bs)
Bs-tagV + Bs-tagU + Bs-tagTProtein2.7.8.M1 (Enzyme Nomenclature) Polyisoprenyl-major teichoic acid -- peptidoglycan teichoic acis transferase
CDP-glycerolMetabolite
CDP-glycerol(n)Metabolite
CMPMetabolite
CMP (n)Metabolite
CTPMetabolite
D-alanineMetabolite
D-alanylMetabolite
Gro-P-ManNac-GlcNAc-PP-undecaprenolMetabolite
H+Metabolite
H+ (n)Metabolite
H2OMetabolite
ManNAc-GlcNAc-PP-undecaprenolMetabolite
N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenolMetabolite
UDPMetabolite
UDP (n)Metabolite
UDP-N-acety-alpha-D-glucosamideMetabolite
UDP-N-acetyl-D-glucosamine biosynthesis IPathway
UDP-N-acetyl-alpha-D-mannosamineMetabolite
UDP-alpha-D-glucose (n)Metabolite
UMPMetabolite
a D-alanyl-carrier proteinProtein
a peptidoglycan-major wall teichoic acid complexMetabolite
a polyisoprenyl-major wall techoic acidMetabolite
an L-1-phosphatidyl-sn-glycerolMetabolite
di-trans,octa-cis-undecaprenyl diphosphate Metabolite
di-trans,octa-cis-undecaprenyl phosphateMetabolite
di-trans,octa-cis-undecaprenyl phosphate Metabolite
diphosphateMetabolite
ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-beta-D-glucosaminyl)-

(1,4-)]-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-

diaminopimeloyl-D-alanyl-D-alanine		Metabolite
phosphateMetabolite
sn-glycerol-3-phosphateMetabolite

Annotated Interactions

No annotated interactions

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