Pathogenic Escherichia coli infection (Homo sapiens)
From WikiPathways
Description
Sources: KEGG
Escherichia coli (commonly abbreviated E. coli) is a gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms (endotherms). Most E. coli strains are harmless, but some serotypes are pathogenic and can cause serious food poisoning in humans, and are occasionally responsible for product recalls. E. coli are also responsible for a majority of cases of urinary tract infections. The harmless strains are part of the normal flora of the gut, and can benefit their hosts by producing vitamin K2, and by preventing the establishment of pathogenic bacteria within the intestine.
This pathway is part the CPTAC Assay Portal.Quality Tags
Ontology Terms
Bibliography
- Kaper, James B., James P. Nataro, Harry LT Mobley.; ''Pathogenic escherichia coli.''; Nature Reviews Microbiology, 2004 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
ABL1 | GeneProduct | 25 (Entrez Gene) | Original kegg element: gene;35;hsa:25 hsa:2534 |
ACTB | GeneProduct | 60 (Entrez Gene) | Original kegg element: gene;55;hsa:60 hsa:71 |
ACTG1 | GeneProduct | 71 (Entrez Gene) | Original kegg element: gene;55;hsa:60 hsa:71 |
ARHGEF2 | GeneProduct | 9181 (Entrez Gene) | Original kegg element: gene;42;hsa:9181 |
ARPC1A | GeneProduct | 10552 (Entrez Gene) | Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873 |
ARPC1B | GeneProduct | 10095 (Entrez Gene) | Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873 |
ARPC2 | GeneProduct | 10109 (Entrez Gene) | Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873 |
ARPC3 | GeneProduct | 10094 (Entrez Gene) | Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873 |
ARPC4 | GeneProduct | 10093 (Entrez Gene) | Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873 |
ARPC5 | GeneProduct | 10092 (Entrez Gene) | Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873 |
ARPC5L | GeneProduct | 81873 (Entrez Gene) | Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873 |
Adherens junction | Pathway | path:hsa04520 (KEGG Genes) | Original kegg element: map;5;path:hsa04520 |
Apoptosis | Pathway | WP254 (WikiPathways) |
|
Bfp | GeneProduct | Q0H044 (Uniprot-TrEMBL) | |
CD14 | GeneProduct | 929 (Entrez Gene) | Original kegg element: gene;2;hsa:929 |
CDC42 | GeneProduct | 998 (Entrez Gene) | Original kegg element: gene;32;hsa:998 |
CDH1 | GeneProduct | 999 (Entrez Gene) | Original kegg element: gene;17;hsa:999 |
CLDN1 | GeneProduct | 9076 (Entrez Gene) | Original kegg element: gene;39;hsa:9076 |
CTNNB1 | GeneProduct | 1499 (Entrez Gene) | Original kegg element: gene;26;hsa:1499 |
CTTN | GeneProduct | 2017 (Entrez Gene) | Original kegg element: gene;27;hsa:2017 hsa:3059 |
EZR | GeneProduct | 7430 (Entrez Gene) | Original kegg element: gene;31;hsa:7430 |
Eae | GeneProduct | P43261 (Uniprot-TrEMBL) | |
EspF | GeneProduct | O85622 (Uniprot-TrEMBL) | |
EspFU | GeneProduct | P0DJ88 (Uniprot-TrEMBL) | |
EspG2 | GeneProduct | Q9EZE8 (Uniprot-TrEMBL) | |
EspG | GeneProduct | O85646 (Uniprot-TrEMBL) | |
EspH | GeneProduct | O85629 (Uniprot-TrEMBL) | |
FYN | GeneProduct | 2534 (Entrez Gene) | Original kegg element: gene;35;hsa:25 hsa:2534 |
Flagellar assembly | Pathway | path:map02040 (KEGG Genes) | Original kegg element: map;4;path:map02040 |
HCLS1 | GeneProduct | 3059 (Entrez Gene) | Original kegg element: gene;27;hsa:2017 hsa:3059 |
ITGB1 | GeneProduct | 3688 (Entrez Gene) | Original kegg element: gene;40;hsa:3688 |
KRT18 | GeneProduct | 3875 (Entrez Gene) | Original kegg element: gene;25;hsa:3875 |
LY96 | GeneProduct | 23643 (Entrez Gene) | Original kegg element: gene;3;hsa:23643 |
Map | GeneProduct | Q9R8E4 (Uniprot-TrEMBL) | |
NCK1 | GeneProduct | 4690 (Entrez Gene) | Original kegg element: gene;41;hsa:4690 hsa:8440 |
NCK2 | GeneProduct | 8440 (Entrez Gene) | Original kegg element: gene;41;hsa:4690 hsa:8440 |
NCL | GeneProduct | 4691 (Entrez Gene) | Original kegg element: gene;45;hsa:4691 |
NleA | GeneProduct | Q71HP5 (Uniprot-TrEMBL) | |
NleH | GeneProduct | D3QNI6 (Uniprot-TrEMBL) | |
OCLN | GeneProduct | 4950 (Entrez Gene) | Original kegg element: gene;30;hsa:100506658 hsa:4950 |
PRKCA | GeneProduct | 5578 (Entrez Gene) | Original kegg element: gene;36;hsa:5578 |
Phosphatidylethanolamine | Metabolite | C00350 (KEGG Compound) | |
RHOA | GeneProduct | 387 (Entrez Gene) | Original kegg element: gene;44;hsa:387 |
ROCK1 | GeneProduct | 6093 (Entrez Gene) | Original kegg element: gene;28;hsa:6093 hsa:9475 |
ROCK2 | GeneProduct | 9475 (Entrez Gene) | Original kegg element: gene;28;hsa:6093 hsa:9475 |
Regulation of actin cytoskeleton | Pathway | WP51 (WikiPathways) |
|
StxA | GeneProduct | A8B1H9 (Uniprot-TrEMBL) | |
StxB | GeneProduct | A7UQX3 (Uniprot-TrEMBL) | |
TLR4 | GeneProduct | 7099 (Entrez Gene) | Original kegg element: gene;9;hsa:7099 |
TLR5 | GeneProduct | 7100 (Entrez Gene) | Original kegg element: gene;10;hsa:7100 |
TUBA1A | GeneProduct | 7846 (Entrez Gene) | Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790 |
TUBA1B | GeneProduct | 10376 (Entrez Gene) | Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790 |
TUBA1C | GeneProduct | 84790 (Entrez Gene) | Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790 |
TUBA3C | GeneProduct | 7278 (Entrez Gene) | Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790 |
TUBA3D | GeneProduct | 113457 (Entrez Gene) | Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790 |
TUBA3E | GeneProduct | 112714 (Entrez Gene) | Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790 |
TUBA4A | GeneProduct | 7277 (Entrez Gene) | Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790 |
TUBA8 | GeneProduct | 51807 (Entrez Gene) | Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790 |
TUBAL3 | GeneProduct | 79861 (Entrez Gene) | Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790 |
TUBB1 | GeneProduct | 81027 (Entrez Gene) | Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617 |
TUBB | GeneProduct | 203068 (Entrez Gene) | Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617 |
TUBB2A | GeneProduct | 7280 (Entrez Gene) | Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617 |
TUBB2B | GeneProduct | 347733 (Entrez Gene) | Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617 |
TUBB2C | GeneProduct | 10383 (Entrez Gene) | Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617 |
TUBB3 | GeneProduct | 10381 (Entrez Gene) | Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617 |
TUBB4 | GeneProduct | 10382 (Entrez Gene) | Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617 |
TUBB4Q | GeneProduct | 56604 (Entrez Gene) | Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617 |
TUBB6 | GeneProduct | 84617 (Entrez Gene) | Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617 |
TUBB8 | GeneProduct | 347688 (Entrez Gene) | Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617 |
Tight junction | Pathway | path:hsa04530 (KEGG Genes) | Original kegg element: map;6;path:hsa04530 |
Tir | GeneProduct | P0DJ92 (Uniprot-TrEMBL) | |
Toll-like receptor signaling pathway | Pathway | WP75 (WikiPathways) |
|
Type III protein secretion system | GeneProduct | Original kegg element: map;4;path:map02040 | |
WAS | GeneProduct | 7454 (Entrez Gene) | Original kegg element: gene;37;hsa:7454 hsa:8976 |
WASL | GeneProduct | 8976 (Entrez Gene) | Original kegg element: gene;37;hsa:7454 hsa:8976 |
YWHAQ | GeneProduct | 10971 (Entrez Gene) | Original kegg element: gene;18;hsa:10971 |
YWHAZ | GeneProduct | 7534 (Entrez Gene) | Original kegg element: gene;23;hsa:7534 |
actin-related protein 2/3 complex subunit 1B-like | GeneProduct | 653888 (Entrez Gene) | Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873 |
occludin-like | GeneProduct | 100506658 (Entrez Gene) | Original kegg element: gene;30;hsa:100506658 hsa:4950 |
Annotated Interactions
No annotated interactions