COVID-19 and endothelial cell senescence (Homo sapiens)
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Bibliography
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- Xia H, Cao Z, Xie X, Zhang X, Chen JY, Wang H, Menachery VD, Rajsbaum R, Shi PY; ''Evasion of Type I Interferon by SARS-CoV-2.''; Cell Rep, 2020 PubMed Europe PMC Scholia
- Xia H, Shi PY; ''Antagonism of Type I Interferon by Severe Acute Respiratory Syndrome Coronavirus 2.''; J Interferon Cytokine Res, 2020 PubMed Europe PMC Scholia
- Yamauchi K, Shibata Y, Kimura T, Abe S, Inoue S, Osaka D, Sato M, Igarashi A, Kubota I; ''Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharideand interferon-gamma stimulated macrophages.''; Int J Biol Sci, 2009 PubMed Europe PMC Scholia
- Ratia K, Pegan S, Takayama J, Sleeman K, Coughlin M, Baliji S, Chaudhuri R, Fu W, Prabhakar BS, Johnson ME, Baker SC, Ghosh AK, Mesecar AD; ''A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication.''; Proc Natl Acad Sci U S A, 2008 PubMed Europe PMC Scholia
- Aghai ZH, Kode A, Saslow JG, Nakhla T, Farhath S, Stahl GE, Eydelman R, Strande L, Leone P, Rahman I; ''Azithromycin suppresses activation of nuclear factor-kappa B and synthesis of pro-inflammatory cytokines in tracheal aspirate cells from premature infants.''; Pediatr Res, 2007 PubMed Europe PMC Scholia
- Ramirez-Ortiz ZG, Prasad A, Griffith JW, Pendergraft WF 3rd, Cowley GS, Root DE, Tai M, Luster AD, El Khoury J, Hacohen N, Means TK; ''The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity.''; Nat Immunol, 2015 PubMed Europe PMC Scholia
- Sa Ribero M, Jouvenet N, Dreux M, Nisole S; ''''; , PubMed Europe PMC Scholia
- Baines KJ, Wright TK, Gibson PG, Powell H, Hansbro PM, Simpson JL; ''Azithromycin treatment modifies airway and blood gene expression networks in neutrophilic COPD.''; ERJ Open Res, 2018 PubMed Europe PMC Scholia
- Baines KJ, Wright TK, Gibson PG, Powell H, Hansbro PM, Simpson JL; ''Azithromycin treatment modifies airway and blood gene expression networks in neutrophilic COPD.''; ERJ Open Res, 2018 PubMed Europe PMC Scholia
- Khanmohammadi S, Rezaei N; ''Role of Toll-like receptors in the pathogenesis of COVID-19.''; J Med Virol, 2021 PubMed Europe PMC Scholia
- Lei X, Dong X, Ma R, Wang W, Xiao X, Tian Z, Wang C, Wang Y, Li L, Ren L, Guo F, Zhao Z, Zhou Z, Xiang Z, Wang J; ''Activation and evasion of type I interferon responses by SARS-CoV-2.''; Nat Commun, 2020 PubMed Europe PMC Scholia
- Edelmann MJ, Nicholson B, Kessler BM; ''Pharmacological targets in the ubiquitin system offer new ways of treating cancer, neurodegenerative disorders and infectious diseases.''; Expert Rev Mol Med, 2011 PubMed Europe PMC Scholia
- Wu X, Xia T, Shin WJ, Yu KM, Jung W, Herrmann A, Foo SS, Chen W, Zhang P, Lee JS, Poo H, Comhair SAA, Jehi L, Choi YK, Ensser A, Jung JU; ''Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8.''; mBio, 2022 PubMed Europe PMC Scholia
- Carter-Timofte ME, Jørgensen SE, Freytag MR, Thomsen MM, Brinck Andersen NS, Al-Mousawi A, Hait AS, Mogensen TH; ''Deciphering the Role of Host Genetics in Susceptibility to Severe COVID-19.''; Front Immunol, 2020 PubMed Europe PMC Scholia
- Gautret P, Lagier JC, Parola P, Hoang VT, Meddeb L, Mailhe M, Doudier B, Courjon J, Giordanengo V, Vieira VE, Dupont HT, Honoré S, Colson P, Chabrière E, La Scola B, Rolain JM, Brouqui P, Raoult D; ''Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial.''; Int J Antimicrob Agents, 2020 PubMed Europe PMC Scholia
- Yamauchi K, Shibata Y, Kimura T, Abe S, Inoue S, Osaka D, Sato M, Igarashi A, Kubota I; ''Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-gamma stimulated macrophages.''; Int J Biol Sci, 2009 PubMed Europe PMC Scholia
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
ANO6 | GeneProduct | ENSG00000177119 (Ensembl) ![]() | |
IL17A | GeneProduct | ENSG00000112115 (Ensembl) ![]() | |
IL17RA | GeneProduct | ENSG00000177663 (Ensembl) ![]() | |
IL17RC | GeneProduct | ENSG00000163702 (Ensembl) ![]() | |
NSP4 | GeneProduct | P0DTD1 (Uniprot-TrEMBL) ![]() | PDB structure for SARS-CoV strain: 6JYT; PRO_0000449622 |
ORF3a | Protein | P0DTC3 (Uniprot-TrEMBL) ![]() | PDB structure for SARS-CoV strain: 6JYT |
ORF8 | GeneProduct | 43740577 (Entrez Gene) ![]() | PDB structure for SARS-CoV strain: 6JYT |
STING pathway in Kawasaki-like disease and COVID-19 | Pathway | WP4961 (WikiPathways) ![]() | |
TLR4 | Protein | O00206 (Uniprot-TrEMBL) ![]() |
Annotated Interactions
No annotated interactions