Pathogenic Escherichia coli infection (Homo sapiens)

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ToxinsEspFNCK1HCLS1CTTNRegulation of actin cytoskeletonCD14TUBB3YWHAQko:K12789ARPC2YWHAZTUBB4NCK2CTNNB1OCLNTUBA8RHOAPhosphatidylethanolamineARPC3ko:K12785NCLMapCLDN1Bacterial secretion systemTLR4TirARPC1BToll-like receptor signaling pathwayPRKCAStxAEspFUACTG1ApoptosisTUBA1CRegulation of actin cytoskeletonTUBA1BROCK2ko:K12784occludin-likeEspHTUBA3EEspGKRT18LY96ARHGEF2ARPC4Tight junctionROCK1TUBA3DARPC5LTUBB2Cko:K12809ABL1Flagellar assemblyTUBB1WASLARPC1ACDC42TUBB4QACTBARPC5EZRBfpko:K12789ITGB1CDH1FYNTUBBTUBA3Cactin-related protein 2/3 complex subunit 1B-likeWASTUBAL3EspG2Adherens junctionTLR5TUBB2Bko:K12786TUBB6TUBB2ATUBA1ATUBA4AStxBko:K12787ko:K12788ko:K12790TUBB8Pathogen: Enteropathogenic escherichia coli (EPEC)Enterohermorrhagic escherichia coli (EHEC)PilusLEE-encoded effectorsnon-LEE-encoded effectorsProphage-carried effectorsType III proteinsecretion systemFlagellinLPSHost: Small intestinal epithelial cell (EPEC)Large intestinal epithelial cell (EHEC)NleHNleA


Description

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Ontology Terms

 

Bibliography

  1. Kaper, James B., James P. Nataro, Harry LT Mobley.; ''Pathogenic escherichia coli.''; Nature Reviews Microbiology, 2004 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
135055view11:59, 2 August 2024EweitzClear cache to fix board height
118427view14:25, 27 May 2021Marvin M2added pubmed id
106514view21:01, 5 September 2019KhanspersModified description
105780view19:43, 15 August 2019KhanspersModified description
97629view10:42, 31 May 2018AMTanOntology Term : 'epithelial cell of large intestine' added !
97628view10:42, 31 May 2018AMTanOntology Term : 'epithelial cell of small intestine' added !
97525view14:11, 24 May 2018AMTanSee below
97523view14:02, 24 May 2018AMTanConverted some nodes to pathway nodes, updated them with our own pathways rather than KEGG genes pathways
95730view21:06, 18 January 2018AlexanderPicoreplaced all kegg ortholog links with uniprot links for ecoli proteins
95729view20:50, 18 January 2018AlexanderPicotesting uniprot for Ecoli
95728view20:49, 18 January 2018AlexanderPicotesting uniprot for Ecoli
95727view20:47, 18 January 2018AlexanderPicotesting uniprot for Ecoli
95377view08:08, 11 December 2017DeSlRemoved last modified part
95376view08:07, 11 December 2017DeSlAdded literature reference
95375view08:03, 11 December 2017DeSlConnected unconnected line.
95374view08:00, 11 December 2017DeSlModified description
95136view02:26, 17 November 2017AlexanderPicoconnected interactions
78594view14:51, 7 January 2015MaintBotadded missing graphIds
71367view18:37, 17 October 2013MaintBotAutomated update of data sources
71225view20:23, 15 October 2013MaintBotUpdated KEGG xrefs
71224view20:20, 15 October 2013MaintBotUpdated KEGG Compound xrefs
68925view17:33, 8 July 2013MaintBotUpdated to 2013 gpml schema
53131view01:51, 30 October 2012AlexanderPicoModified description
53130view01:50, 30 October 2012AlexanderPicoModified categories
53129view01:50, 30 October 2012AlexanderPicoModified categories
50535view03:03, 17 August 2012NsalomonisPeriodical save, work in progress
50465view05:25, 16 August 2012NsalomonisModified description
50464view05:25, 16 August 2012NsalomonisOntology Term : 'pathogenic Escherichia coli infection pathway' added !
50463view05:21, 16 August 2012NsalomonisSpecify description
50462view05:20, 16 August 2012NsalomonisSpecify description
50461view05:16, 16 August 2012NsalomonisSpecify description
50460view05:12, 16 August 2012NsalomonisPeriodical save, work in progress
50459view05:10, 16 August 2012NsalomonisSpecify description
50458view05:02, 16 August 2012NsalomonisPeriodical save, work in progress
50457view04:52, 16 August 2012NsalomonisPeriodical save, work in progress
50454view04:42, 16 August 2012NsalomonisPeriodical save, work in progress
50453view04:31, 16 August 2012NsalomonisPeriodical save, work in progress
50452view04:21, 16 August 2012NsalomonisPeriodical save, work in progress
50445view23:25, 15 August 2012NsalomonisSpecify description
50444view23:23, 15 August 2012NsalomonisSpecify description
50441view23:21, 15 August 2012NsalomonisPeriodical save, work in progress
50436view23:09, 15 August 2012NsalomonisSpecify description
50435view23:06, 15 August 2012NsalomonisSpecify description
50434view22:59, 15 August 2012NsalomonisPeriodical save, work in progress
50433view22:34, 15 August 2012NsalomonisNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABL1GeneProduct25 (Entrez Gene) Original kegg element: gene;35;hsa:25 hsa:2534
ACTBGeneProduct60 (Entrez Gene) Original kegg element: gene;55;hsa:60 hsa:71
ACTG1GeneProduct71 (Entrez Gene) Original kegg element: gene;55;hsa:60 hsa:71
ARHGEF2GeneProduct9181 (Entrez Gene) Original kegg element: gene;42;hsa:9181
ARPC1AGeneProduct10552 (Entrez Gene) Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873
ARPC1BGeneProduct10095 (Entrez Gene) Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873
ARPC2GeneProduct10109 (Entrez Gene) Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873
ARPC3GeneProduct10094 (Entrez Gene) Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873
ARPC4GeneProduct10093 (Entrez Gene) Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873
ARPC5GeneProduct10092 (Entrez Gene) Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873
ARPC5LGeneProduct81873 (Entrez Gene) Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873
Adherens junctionGeneProductpath:hsa04520 (KEGG Genes) Original kegg element: map;5;path:hsa04520
ApoptosisGeneProductpath:hsa04210 (KEGG Genes) Original kegg element: map;19;path:hsa04210
Bacterial secretion systemGeneProductpath:map03070 (KEGG Genes) Original kegg element: map;8;path:map03070
BfpGeneProductK12810 (Kegg ortholog)
CD14GeneProduct929 (Entrez Gene) Original kegg element: gene;2;hsa:929
CDC42GeneProduct998 (Entrez Gene) Original kegg element: gene;32;hsa:998
CDH1GeneProduct999 (Entrez Gene) Original kegg element: gene;17;hsa:999
CLDN1GeneProduct9076 (Entrez Gene) Original kegg element: gene;39;hsa:9076
CTNNB1GeneProduct1499 (Entrez Gene) Original kegg element: gene;26;hsa:1499
CTTNGeneProduct2017 (Entrez Gene) Original kegg element: gene;27;hsa:2017 hsa:3059
EZRGeneProduct7430 (Entrez Gene) Original kegg element: gene;31;hsa:7430
EspFGeneProductK12786 (Kegg ortholog)
EspFUGeneProductK12789 (Kegg ortholog)
EspG2GeneProductK12809 (Kegg ortholog)
EspGGeneProductK12785 (Kegg ortholog)
EspHGeneProductK12788 (Kegg ortholog)
FYNGeneProduct2534 (Entrez Gene) Original kegg element: gene;35;hsa:25 hsa:2534
Flagellar assemblyGeneProductpath:map02040 (KEGG Genes) Original kegg element: map;4;path:map02040
HCLS1GeneProduct3059 (Entrez Gene) Original kegg element: gene;27;hsa:2017 hsa:3059
ITGB1GeneProduct3688 (Entrez Gene) Original kegg element: gene;40;hsa:3688
KRT18GeneProduct3875 (Entrez Gene) Original kegg element: gene;25;hsa:3875
LY96GeneProduct23643 (Entrez Gene) Original kegg element: gene;3;hsa:23643
MapGeneProductK12787 (Kegg ortholog)
NCK1GeneProduct4690 (Entrez Gene) Original kegg element: gene;41;hsa:4690 hsa:8440
NCK2GeneProduct8440 (Entrez Gene) Original kegg element: gene;41;hsa:4690 hsa:8440
NCLGeneProduct4691 (Entrez Gene) Original kegg element: gene;45;hsa:4691
NleAGeneProductK16041 (Kegg ortholog)
NleHGeneProductK16042 (Kegg ortholog)
OCLNGeneProduct4950 (Entrez Gene) Original kegg element: gene;30;hsa:100506658 hsa:4950
PRKCAGeneProduct5578 (Entrez Gene) Original kegg element: gene;36;hsa:5578
PhosphatidylethanolamineMetaboliteC00350 (Kegg Compound)
RHOAGeneProduct387 (Entrez Gene) Original kegg element: gene;44;hsa:387
ROCK1GeneProduct6093 (Entrez Gene) Original kegg element: gene;28;hsa:6093 hsa:9475
ROCK2GeneProduct9475 (Entrez Gene) Original kegg element: gene;28;hsa:6093 hsa:9475
Regulation of actin cytoskeletonGeneProductpath:hsa04810 (KEGG Genes) Original kegg element: map;20;path:hsa04810
StxAGeneProductK11006 (Kegg ortholog)
StxBGeneProductK11007 (Kegg ortholog)
TLR4GeneProduct7099 (Entrez Gene) Original kegg element: gene;9;hsa:7099
TLR5GeneProduct7100 (Entrez Gene) Original kegg element: gene;10;hsa:7100
TUBA1AGeneProduct7846 (Entrez Gene) Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790
TUBA1BGeneProduct10376 (Entrez Gene) Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790
TUBA1CGeneProduct84790 (Entrez Gene) Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790
TUBA3CGeneProduct7278 (Entrez Gene) Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790
TUBA3DGeneProduct113457 (Entrez Gene) Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790
TUBA3EGeneProduct112714 (Entrez Gene) Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790
TUBA4AGeneProduct7277 (Entrez Gene) Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790
TUBA8GeneProduct51807 (Entrez Gene) Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790
TUBAL3GeneProduct79861 (Entrez Gene) Original kegg element: gene;15;hsa:10376 hsa:112714 hsa:113457 hsa:51807 hsa:7277 hsa:7278 hsa:7846 hsa:79861 hsa:84790
TUBB1GeneProduct81027 (Entrez Gene) Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617
TUBBGeneProduct203068 (Entrez Gene) Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617
TUBB2AGeneProduct7280 (Entrez Gene) Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617
TUBB2BGeneProduct347733 (Entrez Gene) Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617
TUBB2CGeneProduct10383 (Entrez Gene) Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617
TUBB3GeneProduct10381 (Entrez Gene) Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617
TUBB4GeneProduct10382 (Entrez Gene) Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617
TUBB4QGeneProduct56604 (Entrez Gene) Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617
TUBB6GeneProduct84617 (Entrez Gene) Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617
TUBB8GeneProduct347688 (Entrez Gene) Original kegg element: gene;47;hsa:10381 hsa:10382 hsa:10383 hsa:203068 hsa:347688 hsa:347733 hsa:56604 hsa:7280 hsa:81027 hsa:84617
Tight junctionGeneProductpath:hsa04530 (KEGG Genes) Original kegg element: map;6;path:hsa04530
TirGeneProductK12784 (Kegg ortholog)
Toll-like receptor signaling pathwayGeneProductpath:hsa04620 (KEGG Genes) Original kegg element: map;7;path:hsa04620
Type III protein secretion systemGeneProductOriginal kegg element: map;4;path:map02040
WASGeneProduct7454 (Entrez Gene) Original kegg element: gene;37;hsa:7454 hsa:8976
WASLGeneProduct8976 (Entrez Gene) Original kegg element: gene;37;hsa:7454 hsa:8976
YWHAQGeneProduct10971 (Entrez Gene) Original kegg element: gene;18;hsa:10971
YWHAZGeneProduct7534 (Entrez Gene) Original kegg element: gene;23;hsa:7534
actin-related protein 2/3 complex subunit 1B-likeGeneProduct653888 (Entrez Gene) Original kegg element: gene;54;hsa:10092 hsa:10093 hsa:10094 hsa:10095 hsa:10109 hsa:10552 hsa:653888 hsa:81873
ko:K12784GeneProductK12784 (Kegg ortholog)
ko:K12785GeneProductK12785 (Kegg ortholog)
ko:K12786GeneProductK12786 (Kegg ortholog)
ko:K12787GeneProductK12787 (Kegg ortholog)
ko:K12788GeneProductK12788 (Kegg ortholog)
ko:K12789GeneProductK12789 (Kegg ortholog)
ko:K12790GeneProductK12790 (Kegg ortholog)
ko:K12809GeneProductK12809 (Kegg ortholog)
occludin-likeGeneProduct100506658 (Entrez Gene) Original kegg element: gene;30;hsa:100506658 hsa:4950

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2272"
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