Eicosanoid metabolism via lipoxygenases (LOX) (Mus musculus)
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Description
This pathway is inspired by the Lipidmaps>Eicosanoids Pathway expended pathway display [1].
Eicosanoids are a large group of compounds metabolised from arachidonic acid (AA), either via cyclooxygenases (COX), lipooxygenases(LOX), or cytochrome P450 monooxygenases(CYP).
This pathway visualises the second route, via LOX.Quality Tags
Ontology Terms
Bibliography
- Dennis EA, Norris PC; ''Eicosanoid storm in infection and inflammation.''; Nat Rev Immunol, 2015 PubMed Europe PMC Scholia
- Lee TH, Menica-Huerta JM, Shih C, Corey EJ, Lewis RA, Austen KF; ''Characterization and biologic properties of 5,12-dihydroxy derivatives of eicosapentaenoic acid, including leukotriene B5 and the double lipoxygenase product.''; J Biol Chem, 1984 PubMed Europe PMC Scholia
- Moreno JJ; ''New aspects of the role of hydroxyeicosatetraenoic acids in cell growth and cancer development.''; Biochem Pharmacol, 2009 PubMed Europe PMC Scholia
- Buczynski MW, Dumlao DS, Dennis EA; ''Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology.''; J Lipid Res, 2009 PubMed Europe PMC Scholia
History
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External references
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Annotated Interactions
No annotated interactions