Autophagy in pancreatic ductal adenocarcinoma (Homo sapiens)
From WikiPathways
Description
This pathway demonstrates autophagy upregulation during pancreatic ductal adenocarcinoma (PDAC). It covers autophagy accumulation as well as how this promotes cell proliferation in tumor microenvironment. Autophagy in PDAC affects mTOR signaling pathways as well as MAPK signaling pathway.
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Ontology Terms
Bibliography
- Congting Guo, Ying Zhao; ''Autophagy in pancreatic cancer''; J Mol Cell Biol ., 2022 PubMed Europe PMC Scholia
- Todoric et al; ''Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas''; Cancer Cell ., 2017 PubMed Europe PMC Scholia
- Maria New, Tim Van Acker, Jaclyn S Long, Jun-Ichi Sakamaki, Kevin M Ryan, Sharon A Tooze; ''Molecular Pathways Controlling Autophagy in Pancreatic Cancer''; Front Oncol ., 2017 PubMed Europe PMC Scholia
- Li et al.; ''Regulation and function of autophagy in pancreatic cancer''; Autophagy ., 2021 PubMed Europe PMC Scholia
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Annotated Interactions
No annotated interactions