Serotonin HTR1 group and FOS pathway (Homo sapiens)

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Description

This pathway depicts the downstream signaling of serotonin via the receptors 1 group, resulting in the production of FOS via ELK-SRF and CREB1. This pathway also shows the downstream signaling of serotonin via receptor 2A, resulting in the activation of STAT3.

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Savchenko V, Sung U, Blakely RD; ''Cell surface trafficking of the antidepressant-sensitive norepinephrine transporter revealed with an ectodomain antibody.''; Mol Cell Neurosci, 2003 PubMed Europe PMC Scholia
Topham MK, Prescott SM; ''Diacylglycerol kinase zeta regulates Ras activation by a novel mechanism.''; J Cell Biol, 2001 PubMed Europe PMC Scholia
van den Berghe N, Cool RH, Wittinghofer A; ''Discriminatory residues in Ras and Rap for guanine nucleotide exchange factor recognition.''; J Biol Chem, 1999 PubMed Europe PMC Scholia
Rishal I, Keren-Raifman T, Yakubovich D, Ivanina T, Dessauer CW, Slepak VZ, Dascal N; ''Na+ promotes the dissociation between Galpha GDP and Gbeta gamma, activating G protein-gated K+ channels.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Linton SP, Scott PH, Kendall MJ; ''Blood sugar and beta-blockers.''; Br Med J, 1976 PubMed Europe PMC Scholia
Tor Erik Rusten, Harald Stenmark; ''Analyzing phosphoinositides and their interacting proteins''; Nat Methods ., 2006 PubMed Europe PMC Scholia
Liprando LA, Miner LH, Blakely RD, Lewis DA, Sesack SR; ''Ultrastructural interactions between terminals expressing the norepinephrine transporter and dopamine neurons in the rat and monkey ventral tegmental area.''; Synapse, 2004 PubMed Europe PMC Scholia
Wang X, Li W, Williams M, Terada N, Alessi DR, Proud CG; ''Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.''; EMBO J, 2001 PubMed Europe PMC Scholia
Roy SK, Hu J, Meng Q, Xia Y, Shapiro PS, Reddy SP, Platanias LC, Lindner DJ, Johnson PF, Pritchard C, Pages G, Pouyssegur J, Kalvakolanu DV; ''MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma.''; Proc Natl Acad Sci U S A, 2002 PubMed Europe PMC Scholia
Jean DH, Albers RW, Guth L, Aron HJ; ''Differences between the heavy chains of fast and slow muscle myosin.''; Exp Neurol, 1975 PubMed Europe PMC Scholia
Jo Y, King SR, Khan SA, Stocco DM; ''Involvement of protein kinase C and cyclic adenosine 3',5'-monophosphate-dependent kinase in steroidogenic acute regulatory protein expression and steroid biosynthesis in Leydig cells.''; Biol Reprod, 2005 PubMed Europe PMC Scholia
Budnik LT, Brunswig-Spickenheier B, Mukhopadhyay AK; ''Lysophosphatidic acid signals through mitogen-activated protein kinase-extracellular signal regulated kinase in ovarian theca cells expressing the LPA1/edg2-receptor: involvement of a nonclassical pathway?''; Mol Endocrinol, 2003 PubMed Europe PMC Scholia
Roberts DM, Anderson AL, Hidaka M, Swetenburg RL, Patterson C, Stanford WL, Bautch VL; ''A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters.''; Mol Cell Biol, 2004 PubMed Europe PMC Scholia
Karin M; ''The regulation of AP-1 activity by mitogen-activated protein kinases.''; J Biol Chem, 1995 PubMed Europe PMC Scholia
Most P, Boerries M, Eicher C, Schweda C, Ehlermann P, Pleger ST, Loeffler E, Koch WJ, Katus HA, Schoenenberger CA, Remppis A, Black IB, Mytilineou C; ''Trans-synaptic regulation of the development of end organ innervation by sympathetic neurons.''; Brain Res, 1976 PubMed Europe PMC Scholia
Froger N, Gardier AM, Moratalla R, Alberti I, Lena I, Boni C, De Felipe C, Rupniak NM, Hunt SP, Jacquot C, Hamon M, Lanfumey L; ''5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization.''; J Neurosci, 2001 PubMed Europe PMC Scholia
Puente LG, Stone JC, Ostergaard HL; ''Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins.''; J Immunol, 2000 PubMed Europe PMC Scholia
Corbit KC, Soh JW, Yoshida K, Eves EM, Weinstein IB, Rosner MR, Doublet MO, Olomucki A; ''Investigations on the kinetic mechanism of octopine dehydrogenase. 1. Steady-state kinetics.''; Eur J Biochem, 1975 PubMed Europe PMC Scholia
Hultberg B, Masson PK; ''Activation of residual acidic alpha-mannosidase activity in mannosidosis tissues by metal ions.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Yamashita S, Mochizuki N, Ohba Y, Tobiume M, Okada Y, Sawa H, Nagashima K, Matsuda M; ''CalDAG-GEFIII activation of Ras, R-ras, and Rap1.''; J Biol Chem, 2000 PubMed Europe PMC Scholia
Patterson RL, van Rossum DB, Kaplin AI, Barrow RK, Snyder SH; ''Inositol 1,4,5-trisphosphate receptor/GAPDH complex augments Ca2+ release via locally derived NADH.''; Proc Natl Acad Sci U S A, 2005 PubMed Europe PMC Scholia
Vermeulen L, De Wilde G, Van Damme P, Vanden Berghe W, Haegeman G, Rozengurt E, Heppel LA; ''A Specific effect of external ATP on the permeability of transformed 3T3 cells.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Dutil EM, Newton AC; ''Dual role of pseudosubstrate in the coordinated regulation of protein kinase C by phosphorylation and diacylglycerol.''; J Biol Chem, 2000 PubMed Europe PMC Scholia
Ninomiya H, Otani H, Lu K, Uchiyama T, Kido M, Imamura H; ''Enhanced IPC by activation of pertussis toxin-sensitive and -insensitive G protein-coupled purinoceptors.''; Am J Physiol Heart Circ Physiol, 2002 PubMed Europe PMC Scholia
Guan Z, Buckman SY, Springer LD, Morrison AR; ''Both p38alpha(MAPK) and JNK/SAPK pathways are important for induction of nitric-oxide synthase by interleukin-1beta in rat glomerular mesangial cells.''; J Biol Chem, 1999 PubMed Europe PMC Scholia
Sung U, Apparsundaram S, Galli A, Kahlig KM, Savchenko V, Schroeter S, Quick MW, Blakely RD; ''A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity.''; J Neurosci, 2003 PubMed Europe PMC Scholia
Roberts EC, Shapiro PS, Nahreini TS, Pages G, Pouyssegur J, Ahn NG, Nijjar MS, Pritchard ET; ''Incorporation of (1-14C)palmitoyl-CoA into phosphatidylcholine by plasma membranes of rat submaxillary glands in vitro.''; Eur J Biochem, 1976 PubMed Europe PMC Scholia
Ratner NA, Vikhert AM, Abugova SP, Arabidze GG, Matveeva LS; ''Problems of the pathogenesis, clinics, and therapy of panarteritis of the aorta and its branches.''; Cor Vasa, 1975 PubMed Europe PMC Scholia
Herrick-Davis K, Titeler M, Leonhardt S, Struble R, Price D; ''Serotonin 5-HT1D receptors in human prefrontal cortex and caudate: interaction with a GTP binding protein.''; J Neurochem, 1988 PubMed Europe PMC Scholia
Oxford GS, Webb CK; ''GoLoco motif peptides as probes of Galpha subunit specificity in coupling of G-protein-coupled receptors to ion channels.''; Methods Enzymol, 2004 PubMed Europe PMC Scholia
Xu S, Khoo S, Dang A, Witt S, Do V, Zhen E, Schaefer EM, Cobb MH; ''Differential regulation of mitogen-activated protein/ERK kinase (MEK)1 and MEK2 and activation by a Ras-independent mechanism.''; Mol Endocrinol, 1997 PubMed Europe PMC Scholia
Hattori R, Maulik N, Otani H, Zhu L, Cordis G, Engelman RM, Siddiqui MA, Das DK; ''Role of STAT3 in ischemic preconditioning.''; J Mol Cell Cardiol, 2001 PubMed Europe PMC Scholia
Malaspina A, Kaushik N, de Belleroche J, De Sagher RM, De Leenheer AP, Cruyl AA, Claeys AE; ''Identification and urinary excretion of p-chlorophenoxyacetamide, a metabolite of iproclozide, in humans.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
Guo FF, Kumahara E, Saffen D; ''A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Eblen ST, Slack JK, Weber MJ, Catling AD; ''Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes.''; Mol Cell Biol, 2002 PubMed Europe PMC Scholia
Hatakeyama M, Yumoto N, Yu X, Shirouzu M, Yokoyama S, Konagaya A; ''Transformation potency of ErbB heterodimer signaling is determined by B-Raf kinase.''; Oncogene, 2004 PubMed Europe PMC Scholia
Prasad HC, Zhu CB, McCauley JL, Samuvel DJ, Ramamoorthy S, Shelton RC, Hewlett WA, Sutcliffe JS, Blakely RD; ''Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase.''; Proc Natl Acad Sci U S A, 2005 PubMed Europe PMC Scholia
Enarsson M, Erlandsson A, Larsson H, Forsberg-Nilsson K, Takegami T, Yoshida K; ''Isolation and purification of cytokinin binding protein from tobacco leaves by affinity column chromatography.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Banihashemi B, Albert PR; ''Dopamine-D2S receptor inhibition of calcium influx, adenylyl cyclase, and mitogen-activated protein kinase in pituitary cells: distinct Galpha and Gbetagamma requirements.''; Mol Endocrinol, 2002 PubMed Europe PMC Scholia
Deng J, Chen Y, Wu R; ''Induction of cell cornification and enhanced squamous-cell marker SPRR1 gene expression by phorbol ester are regulated by different signaling pathways in human conducting airway epithelial cells.''; Am J Respir Cell Mol Biol, 2000 PubMed Europe PMC Scholia
Funakoshi Y, Ichiki T, Takeda K, Tokuno T, Iino N, Takeshita A, Schneider AB, Kowalski K, Sherwood LM; ''Identification of "big" human placental lactogen in placenta and serum.''; Endocrinology, 1975 PubMed Europe PMC Scholia
Bergmeier W, Goerge T, Wang HW, Crittenden JR, Baldwin AC, Cifuni SM, Housman DE, Graybiel AM, Wagner DD; ''Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.''; J Clin Invest, 2007 PubMed Europe PMC Scholia
Papin C, Eychene A, Brunet A, Pages G, Pouyssegur J, Calothy G, Barnier JV; ''B-Raf protein isoforms interact with and phosphorylate Mek-1 on serine residues 218 and 222.''; Oncogene, 1995 PubMed Europe PMC Scholia
Jayaraman T, Ondrias K, Ondriasová E, Marks AR; ''Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation.''; Science, 1996 PubMed Europe PMC Scholia
Serrano CJ, Graham L, DeBell K, Rawat R, Veri MC, Bonvini E, Rellahan BL, Reischl IG; ''A new tyrosine phosphorylation site in PLC gamma 1: the role of tyrosine 775 in immune receptor signaling.''; J Immunol, 2005 PubMed Europe PMC Scholia
Silverman E, Frodin M, Gammeltoft S, Maller JL; ''''; , PubMed Europe PMC Scholia
Ryder JW, Fahlman R, Wallberg-Henriksson H, Alessi DR, Krook A, Zierath JR, Bemski G; ''Study of the heat treatment of hemoglobin by means of spin labels.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Balasubramanian S, Efimova T, Eckert RL; ''Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
Zhu CB, Carneiro AM, Dostmann WR, Hewlett WA, Blakely RD; ''p38 MAPK activation elevates serotonin transport activity via a trafficking-independent, protein phosphatase 2A-dependent process.''; J Biol Chem, 2005 PubMed Europe PMC Scholia
Huber M, Hughes MR, Krystal G; ''Thapsigargin-induced degranulation of mast cells is dependent on transient activation of phosphatidylinositol-3 kinase.''; J Immunol, 2000 PubMed Europe PMC Scholia
Franke B, van Triest M, de Bruijn KM, van Willigen G, Nieuwenhuis HK, Negrier C, Akkerman JW, Bos JL; ''Sequential regulation of the small GTPase Rap1 in human platelets.''; Mol Cell Biol, 2000 PubMed Europe PMC Scholia
Liss E, Robertson A; ''The distribution and elimination of radioactivity in the rat after administration of 14C-4-acetamidophenyl-2-acetoxybenzoate (benorylate).''; Arzneimittelforschung, 1975 PubMed Europe PMC Scholia
Jacquet E, Vanoni M, Ferrari C, Alberghina L, Martegani E, Parmeggiani A; ''A mouse CDC25-like product enhances the formation of the active GTP complex of human ras p21 and Saccharomyces cerevisiae RAS2 proteins.''; J Biol Chem, 1992 PubMed Europe PMC Scholia
Cuenda A, Dorow DS; ''Differential activation of stress-activated protein kinase kinases SKK4/MKK7 and SKK1/MKK4 by the mixed-lineage kinase-2 and mitogen-activated protein kinase kinase (MKK) kinase-1.''; Biochem J, 1998 PubMed Europe PMC Scholia
Bai Y, Edamatsu H, Maeda S, Saito H, Suzuki N, Satoh T, Kataoka T; ''Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development.''; Cancer Res, 2004 PubMed Europe PMC Scholia
Grambihler A, Higuchi H, Bronk SF, Gores GJ; ''cFLIP-L inhibits p38 MAPK activation: an additional anti-apoptotic mechanism in bile acid-mediated apoptosis.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Khoo S, Cobb MH, Smith RJ, Bryant RG; ''Metal substitutions incarbonic anhydrase: a halide ion probe study.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Marquet A, Nieto M, Diaz-Mauriño T; ''Membrane-bound DD-carboxypeptidase and transpeptidase activities from Bacillus megaterium KM at pH 7. General properties, substrate specificity and inhibition by beta-lactam antibiotics.''; Eur J Biochem, 1976 PubMed Europe PMC Scholia
Balasubramanian S, Efimova T, Eckert RL; ''Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
Doublet MO, Olomucki A; ''Investigations on the kinetic mechanism of octopine dehydrogenase. 1. Steady-state kinetics.''; Eur J Biochem, 1975 PubMed Europe PMC Scholia
Iwamoto H, Blakely RD, De Felice LJ; ''Na+, Cl-, and pH dependence of the human choline transporter (hCHT) in Xenopus oocytes: the proton inactivation hypothesis of hCHT in synaptic vesicles.''; J Neurosci, 2006 PubMed Europe PMC Scholia
Lee YN, Malbon CC, Wang HY; ''G alpha 13 signals via p115RhoGEF cascades regulating JNK1 and primitive endoderm formation.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
Shiraishi M, Hirasawa N, Kobayashi Y, Oikawa S, Murakami A, Ohuchi K, Wiesmann UN, DiDonato S, Herschkowitz NN; ''Effect of chloroquine on cultured fibroblasts: release of lysosomal hydrolases and inhibition of their uptake.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Deacon K, Blank JL; ''Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo.''; J Biol Chem, 1997 PubMed Europe PMC Scholia
Swarthout JT, Doggett TA, Lemker JL, Partridge NC, Mashiter KE, Morgan MR; ''Carbonic anhydrase levels in the tissues of flounders adapted to sea water and fresh water.''; Comp Biochem Physiol A Comp Physiol, 1975 PubMed Europe PMC Scholia
Yamauchi J, Tsujimoto G, Kaziro Y, Itoh H; ''Parallel regulation of mitogen-activated protein kinase kinase 3 (MKK3) and MKK6 in Gq-signaling cascade.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Lanfumey L, Hamon M; ''5-HT1 receptors.''; Curr Drug Targets CNS Neurol Disord, 2004 PubMed Europe PMC Scholia
Goppelt-Struebe M, Stroebel M; ''Mechanisms of serotonin-induced Ca2+ responses in mesangial cells.''; Naunyn Schmiedebergs Arch Pharmacol, 1997 PubMed Europe PMC Scholia
Sommers CL, Lee J, Steiner KL, Gurson JM, Depersis CL, El-Khoury D, Fuller CL, Shores EW, Love PE, Samelson LE; ''Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection.''; J Exp Med, 2005 PubMed Europe PMC Scholia
Hirasawa N, Ohuchi K, Bose KS, Sarma RH; ''Delineation of the intimate details of the backbone conformation of pyridine nucleotide coenzymes in aqueous solution.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Craxton A, Shu G, Graves JD, Saklatvala J, Krebs EG, Clark EA, Stone WN, Green BL, Gleser GC, Whitman RM, Foster BB; ''Impact of psychosocial factors on the conduct of combined drug and psychotherapy research.''; Br J Psychiatry, 1975 PubMed Europe PMC Scholia
Rong R, Ahn JY, Chen P, Suh PG, Ye K; ''Phospholipase activity of phospholipase C-gamma1 is required for nerve growth factor-regulated MAP kinase signaling cascade in PC12 cells.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Brys R, Josson K, Castelli MP, Jurzak M, Lijnen P, Gommeren W, Leysen JE; ''Reconstitution of the human 5-HT(1D) receptor-G-protein coupling: evidence for constitutive activity and multiple receptor conformations.''; Mol Pharmacol, 2000 PubMed Europe PMC Scholia
New L, Zhao M, Li Y, Bassett WW, Feng Y, Ludwig S, Padova FD, Gram H, Han J, Anderson TR, Slotkin TA; ''Maturation of the adrenal medulla--IV. Effects of morphine.''; Biochem Pharmacol, 1975 PubMed Europe PMC Scholia
Johnson NL, Gardner AM, Diener KM, Lange-Carter CA, Gleavy J, Jarpe MB, Minden A, Karin M, Zon LI, Johnson GL; ''Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death.''; J Biol Chem, 1996 PubMed Europe PMC Scholia
Brunet A, Roux D, Lenormand P, Dowd S, Keyse S, Pouyssegur J, Tsukamoto I, Yoshinaga T, Sano S; ''Evidence for histidine as another functional group of delta-aminolevulinic acid dehydratase from beef liver.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Clerk A, Michael A, Sugden PH, Brosseau BL; ''Restraint may force quicker cost-sharing.''; Dimens Health Serv, 1976 PubMed Europe PMC Scholia
Umenishi F, Schrier RW; ''Hypertonicity-induced aquaporin-1 (AQP1) expression is mediated by the activation of MAPK pathways and hypertonicity-responsive element in the AQP1 gene.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Kimoto M, Shirouzu M, Mizutani S, Koide H, Kaziro Y, Hirao I, Yokoyama S; ''Anti-(Raf-1) RNA aptamers that inhibit Ras-induced Raf-1 activation.''; Eur J Biochem, 2002 PubMed Europe PMC Scholia
Brys R, Josson K, Castelli MP, Jurzak M, Lijnen P, Gommeren W, Leysen JE; ''Reconstitution of the human 5-HT(1D) receptor-G-protein coupling: evidence for constitutive activity and multiple receptor conformations.''; Mol Pharmacol, 2000 PubMed Europe PMC Scholia
Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z, Smith A, Lough AK; ''Micellar solubilization of fatty acids in aqueous media containing bile salts and phospholipids.''; Br J Nutr, 1976 PubMed Europe PMC Scholia
Ryder JW, Fahlman R, Wallberg-Henriksson H, Alessi DR, Krook A, Zierath JR, Zalkin H, Murphy T; ''Utilization of ammonia for tryptophan synthesis.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Ben-Levy R, Leighton IA, Doza YN, Attwood P, Morrice N, Marshall CJ, Cohen P, Chow YW, Pietranico R, Mukerji A; ''Studies of oxygen binding energy to hemoglobin molecule.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Chang RL, Zampaglione N, Lin C; ''Correlation of 14C-griseofulvin metabolism in rat liver microsomes, isolated perfused rat livers, and in rats with bile duct cannulas.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
Gendron FP, Neary JT, Theiss PM, Sun GY, Gonzalez FA, Weisman GA, Davison TF, Langslow DR; ''Changes in plasma glucose and liver glycogen following the administration of gluconeogenic precursors to the starving fowl.''; Comp Biochem Physiol A Comp Physiol, 1975 PubMed Europe PMC Scholia
Raymond JR, Mukhin YV, Gelasco A, Turner J, Collinsworth G, Gettys TW, Grewal JS, Garnovskaya MN; ''Multiplicity of mechanisms of serotonin receptor signal transduction.''; Pharmacol Ther, 2001 PubMed Europe PMC Scholia
Zhong XP, Hainey EA, Olenchock BA, Zhao H, Topham MK, Koretzky GA; ''Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
Enslen H, Brancho DM, Davis RJ; ''Molecular determinants that mediate selective activation of p38 MAP kinase isoforms.''; EMBO J, 2000 PubMed Europe PMC Scholia
Tokunou T, Ichiki T, Takeda K, Funakoshi Y, Iino N, Takeshita A, Klimpel GR, Day KD, Lucas DO; ''Differential production of interferon and lymphotoxin by human tonsil lymphocytes.''; Cell Immunol, 1975 PubMed Europe PMC Scholia
Chan AS, Wong YH; ''Regulation of c-Jun N-terminal kinase by the ORL(1) receptor through multiple G proteins.''; J Pharmacol Exp Ther, 2000 PubMed Europe PMC Scholia
Steiner JA, Carneiro AM, Blakely RD; ''Going with the flow: trafficking-dependent and -independent regulation of serotonin transport.''; Traffic, 2008 PubMed Europe PMC Scholia
Sossey-Alaoui K, Li X, Ranalli TA, Cowell JK; ''WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase.''; J Biol Chem, 2005 PubMed Europe PMC Scholia
Dashti SR, Efimova T, Eckert RL; ''MEK6 regulates human involucrin gene expression via a p38alpha - and p38delta -dependent mechanism.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Stadheim TA, Xiao H, Eastman A; ''Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells.''; Cancer Res, 2001 PubMed Europe PMC Scholia
Smith JL, Collins I, Chandramouli GV, Butscher WG, Zaitseva E, Freebern WJ, Haggerty CM, Doseeva V, Gardner K, Reid G; ''Statistical insight through H.I.S.''; Dimens Health Serv, 1976 PubMed Europe PMC Scholia
Dillon TJ, Karpitski V, Wetzel SA, Parker DC, Shaw AS, Stork PJ; ''Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Newman-Tancredi A, Cussac D, Marini L, Millan MJ; ''Antibody capture assay reveals bell-shaped concentration-response isotherms for h5-HT(1A) receptor-mediated Galpha(i3) activation: conformational selection by high-efficacy agonists, and relationship to trafficking of receptor signaling.''; Mol Pharmacol, 2002 PubMed Europe PMC Scholia
Carey KD, Watson RT, Pessin JE, Stork PJ; ''The requirement of specific membrane domains for Raf-1 phosphorylation and activation.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Charvet C, Auberger P, Tartare-Deckert S, Bernard A, Deckert M, Kashmiri SV, Hotchkiss RD; ''Evidence of tandem duplication of genes in a merodiploid region of Pneumococcal mutants resistant to sulfonamide.''; Genetics, 1975 PubMed Europe PMC Scholia
Tao J, Sanghera JS, Pelech SL, Wong G, Levy JG; ''Editorial: Bronchiectasis today.''; Br Med J, 1975 PubMed Europe PMC Scholia
Cobb MH, Goldsmith EJ; ''How MAP kinases are regulated.''; J Biol Chem, 1995 PubMed Europe PMC Scholia
Ahmed I, Gesty-Palmer D, Drezner MK, Luttrell LM; ''Transactivation of the epidermal growth factor receptor mediates parathyroid hormone and prostaglandin F2 alpha-stimulated mitogen-activated protein kinase activation in cultured transgenic murine osteoblasts.''; Mol Endocrinol, 2003 PubMed Europe PMC Scholia
Gupta P, Prywes R, Marshall RJ, Parratt JR; ''Antiarrhythmic, haemodynamic and metabolic effects of 3alpha-amino-5alpha-androstan-2beta-ol-17-one hydrochloride in greyhounds following acute coronary artery ligation.''; Br J Pharmacol, 1975 PubMed Europe PMC Scholia
Parra M, Lluís F, Miralles F, Caelles C, Muñoz-Cánoves P; ''The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG.''; Blood, 2000 PubMed Europe PMC Scholia
Kartha S, Naureckas ET, Li J, Hershenson MB; ''Partial characterization of a novel mitogen-activated protein kinase/extracellular signal-regulated kinase activator in airway smooth-muscle cells.''; Am J Respir Cell Mol Biol, 1999 PubMed Europe PMC Scholia
Carneiro AM, Blakely RD; ''Serotonin-, protein kinase C-, and Hic-5-associated redistribution of the platelet serotonin transporter.''; J Biol Chem, 2006 PubMed Europe PMC Scholia
Ferry X, Eichwald V, Daeffler L, Landry Y; ''Activation of betagamma subunits of G(i2) and G(i3) proteins by basic secretagogues induces exocytosis through phospholipase Cbeta and arachidonate release through phospholipase Cgamma in mast cells.''; J Immunol, 2001 PubMed Europe PMC Scholia
Dipace C, Sung U, Binda F, Blakely RD, Galli A; ''Amphetamine induces a calcium/calmodulin-dependent protein kinase II-dependent reduction in norepinephrine transporter surface expression linked to changes in syntaxin 1A/transporter complexes.''; Mol Pharmacol, 2007 PubMed Europe PMC Scholia
Neufeld B, Grosse-Wilde A, Hoffmeyer A, Jordan BW, Chen P, Dinev D, Ludwig S, Rapp UR, Smith A, Lough AK; ''Micellar solubilization of fatty acids in aqueous media containing bile salts and phospholipids.''; Br J Nutr, 1976 PubMed Europe PMC Scholia
Cuenda A, Dorow DS; ''Differential activation of stress-activated protein kinase kinases SKK4/MKK7 and SKK1/MKK4 by the mixed-lineage kinase-2 and mitogen-activated protein kinase kinase (MKK) kinase-1.''; Biochem J, 1998 PubMed Europe PMC Scholia
Guillet-Deniau I, Burnol AF, Girard J; ''Identification and localization of a skeletal muscle secrotonin 5-HT2A receptor coupled to the Jak/STAT pathway.''; J Biol Chem, 1997 PubMed Europe PMC Scholia
Nguyen BT, Yang L, Sanborn BM, Dessauer CW; ''Phosphoinositide 3-kinase activity is required for biphasic stimulation of cyclic adenosine 3',5'-monophosphate by relaxin.''; Mol Endocrinol, 2003 PubMed Europe PMC Scholia
Winston BW, Chan ED, Johnson GL, Riches DW; ''Activation of p38mapk, MKK3, and MKK4 by TNF-alpha in mouse bone marrow-derived macrophages.''; J Immunol, 1997 PubMed Europe PMC Scholia
Barbhaiya RH, Turner P; ''Fluorimetric determination of cephalexin.''; J Pharm Pharmacol, 1976 PubMed Europe PMC Scholia
Piera MJ, Beaughard M, Michelin MT, Winslow E, Massingham R; ''Lack of efficacy of 5-HT2A receptor antagonists to reduce brain damage after 3 minutes of transient global cerebral ischaemia in gerbils.''; Fundam Clin Pharmacol, 1995 PubMed Europe PMC Scholia
Li Q, Muma NA, Battaglia G, Van de Kar LD; ''Fluoxetine gradually increases [125I]DOI-labelled 5-HT2A/2C receptors in the hypothalamus without changing the levels of Gq- and G11-proteins.''; Brain Res, 1997 PubMed Europe PMC Scholia
Pugazhenthi S, Miller E, Sable C, Young P, Heidenreich KA, Boxer LM, Reusch JE, Nadeau D, Marchand C; ''Change in the kinetics of sulphacetamide tissue distribution in Walker tumor-bearing rats.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
Corbit KC, Foster DA, Rosner MR; ''Protein kinase Cdelta mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells.''; Mol Cell Biol, 1999 PubMed Europe PMC Scholia
Wang R, Zhang L, Yin D, Mufson RA, Shi Y; ''Protein kinase C regulates Fas (CD95/APO-1) expression.''; J Immunol, 1998 PubMed Europe PMC Scholia
Kim HL, Vander Griend DJ, Yang X, Benson DA, Dubauskas Z, Yoshida BA, Chekmareva MA, Ichikawa Y, Sokoloff MH, Zhan P, Karrison T, Lin A, Stadler WM, Ichikawa T, Rubin MA, Rinker-Schaeffer CW; ''Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers.''; Cancer Res, 2001 PubMed Europe PMC Scholia
Kim HL, Vander Griend DJ, Yang X, Benson DA, Dubauskas Z, Yoshida BA, Chekmareva MA, Ichikawa Y, Sokoloff MH, Zhan P, Karrison T, Lin A, Stadler WM, Ichikawa T, Rubin MA, Rinker-Schaeffer CW; ''Mitogen-activated protein kinase kinase 4 metastasis suppressor gene expression is inversely related to histological pattern in advancing human prostatic cancers.''; Cancer Res, 2001 PubMed Europe PMC Scholia
Browning DD, McShane MP, Marty C, Ye RD; ''Nitric oxide activation of p38 mitogen-activated protein kinase in 293T fibroblasts requires cGMP-dependent protein kinase.''; J Biol Chem, 2000 PubMed Europe PMC Scholia
Yosimichi G, Nakanishi T, Nishida T, Hattori T, Takano-Yamamoto T, Takigawa M; ''CTGF/Hcs24 induces chondrocyte differentiation through a p38 mitogen-activated protein kinase (p38MAPK), and proliferation through a p44/42 MAPK/extracellular-signal regulated kinase (ERK).''; Eur J Biochem, 2001 PubMed Europe PMC Scholia
Sung JY, Shin SW, Ahn YS, Chung KC, Stavchansky SA, Kostenbauder HB, Lubawy WC; ''Kinetic and spectral studies of type I and type II compounds with rat hepatic microsomes in the presence of the major metabolite of diphenylhydantoin.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
Xia Y, Wu Z, Su B, Murray B, Karin M; ''JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension.''; Genes Dev, 1998 PubMed Europe PMC Scholia
Banihashemi B, Albert PR; ''Dopamine-D2S receptor inhibition of calcium influx, adenylyl cyclase, and mitogen-activated protein kinase in pituitary cells: distinct Galpha and Gbetagamma requirements.''; Mol Endocrinol, 2002 PubMed Europe PMC Scholia
Quilliam LA, Hisaka MM, Zhong S, Lowry A, Mosteller RD, Han J, Drugan JK, Broek D, Campbell SL, Der CJ; ''Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors.''; J Biol Chem, 1996 PubMed Europe PMC Scholia
Garcia J, de Gunzburg J, Eychène A, Gisselbrecht S, Porteu F; ''Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways.''; Mol Cell Biol, 2001 PubMed Europe PMC Scholia
Bishop PE, McParland RH, Evans HJ; ''Inhibition of the adenylylation of glutamine synthetase by methionine sulfone during nitrogenase derepression.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Smith JL, Collins I, Chandramouli GV, Butscher WG, Zaitseva E, Freebern WJ, Haggerty CM, Doseeva V, Gardner K, Rozovsky LE; ''Order and disorder at hospital meetings.''; Dimens Health Serv, 1975 PubMed Europe PMC Scholia
Cárdenas C, Müller M, Jaimovich E, Pérez F, Buchuk D, Quest AF, Carrasco MA; ''Depolarization of skeletal muscle cells induces phosphorylation of cAMP response element binding protein via calcium and protein kinase Calpha.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
Imada-Shirakata Y, Kotera T, Ueda S, Okuma M; ''Serotonin activates electrolyte transport via 5-HT2A receptor in rat colonic crypt cells.''; Biochem Biophys Res Commun, 1997 PubMed Europe PMC Scholia
Stadheim TA, Xiao H, Eastman A; ''Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells.''; Cancer Res, 2001 PubMed Europe PMC Scholia
Carneiro AM, Cook EH, Murphy DL, Blakely RD; ''Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans.''; J Clin Invest, 2008 PubMed Europe PMC Scholia
Edlund S, Bu S, Schuster N, Aspenstrom P, Heuchel R, Heldin NE, ten Dijke P, Heldin CH, Landstrom M; ''Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3.''; Mol Biol Cell, 2003 PubMed Europe PMC Scholia
Ebinu JO, Stang SL, Teixeira C, Bottorff DA, Hooton J, Blumberg PM, Barry M, Bleakley RC, Ostergaard HL, Stone JC; ''RasGRP links T-cell receptor signaling to Ras.''; Blood, 2000 PubMed Europe PMC Scholia
Syu LJ, Guan KL, Saltiel AR; ''Inducible expression of a mutant form of MEK1 in Swiss 3T3 cells.''; J Cell Biochem, 1997 PubMed Europe PMC Scholia
Lapierre YD, Lee M; ''Piperacetazine in the treatment of mixed neurotics.''; Curr Ther Res Clin Exp, 1976 PubMed Europe PMC Scholia
Mizutani S, Inouye K, Koide H, Kaziro Y; ''Involvement of B-Raf in Ras-induced Raf-1 activation.''; FEBS Lett, 2001 PubMed Europe PMC Scholia
Read MA, Whitley MZ, Gupta S, Pierce JW, Best J, Davis RJ, Collins T; ''Tumor necrosis factor alpha-induced E-selectin expression is activated by the nuclear factor-kappaB and c-JUN N-terminal kinase/p38 mitogen-activated protein kinase pathways.''; J Biol Chem, 1997 PubMed Europe PMC Scholia
Vossler MR, Yao H, York RD, Pan MG, Rim CS, Stork PJ; ''cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway.''; Cell, 1997 PubMed Europe PMC Scholia
Mattingly RR, Macara IG; ''Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits.''; Nature, 1996 PubMed Europe PMC Scholia
Jallon JM, Risler Y, Iwatsubo M; ''Beef liver L-Glutamate dehydrogenase mechanism: presteady state study of the catalytic reduction of 2.oxoglutarate by NADPH.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Simonnet H, Martel MB; ''[Sialyltransferase in human malignant melanoma]''; Clin Chim Acta, 1976 PubMed Europe PMC Scholia
Meisler MH; ''Inhibition of human liver beta-galactosidases and beta-glucosidase by n-bromoacetyl-beta-D-galactosylamine.''; Biochim Biophys Acta, 1975 PubMed Europe PMC Scholia
Zhu CB, Blakely RD, Hewlett WA; ''The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters.''; Neuropsychopharmacology, 2006 PubMed Europe PMC Scholia
Goel R, Phillips-Mason PJ, Gardner A, Raben DM, Baldassare JJ; ''Alpha-thrombin-mediated phosphatidylinositol 3-kinase activation through release of Gbetagamma dimers from Galphaq and Galphai2.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
Gum RJ, Gaede LL, Heindel MA, Waring JF, Trevillyan JM, Zinker BA, Stark ME, Wilcox D, Jirousek MR, Rondinone CM, Ulrich RG; ''Antisense protein tyrosine phosphatase 1B reverses activation of p38 mitogen-activated protein kinase in liver of ob/ob mice.''; Mol Endocrinol, 2003 PubMed Europe PMC Scholia
Chen J, DeVivo M, Dingus J, Harry A, Li J, Sui J, Carty DJ, Blank JL, Exton JH, Stoffel RH; ''A region of adenylyl cyclase 2 critical for regulation by G protein beta gamma subunits.''; Science, 1995 PubMed Europe PMC Scholia
Tournier C, Whitmarsh AJ, Cavanagh J, Barrett T, Davis RJ, Davis SS, Scobie S, Inglis A; ''The effect of sulphydryl compounds and cross linking agents on the viscous and viscoelastic properties of mucus.''; Biorheology, 1975 PubMed Europe PMC Scholia
Papin C, Denouel A, Calothy G, Eychene A; ''Identification of signalling proteins interacting with B-Raf in the yeast two-hybrid system.''; Oncogene, 1996 PubMed Europe PMC Scholia
Yamamori B, Kuroda S, Shimizu K, Fukui K, Ohtsuka T, Takai Y; ''Purification of a Ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins.''; J Biol Chem, 1995 PubMed Europe PMC Scholia
Murata S, Usuda N, Okano A, Kobayashi S, Suzuki T; ''Occurrence of a transcription factor, signal transducer and activators of transcription 3 (Stat3), in the postsynaptic density of the rat brain.''; Brain Res Mol Brain Res, 2000 PubMed Europe PMC Scholia
Zanke BW, Rubie EA, Winnett E, Chan J, Randall S, Parsons M, Boudreau K, McInnis M, Yan M, Templeton DJ, Woodgett JR; ''Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes.''; J Biol Chem, 1996 PubMed Europe PMC Scholia
Yamauchi J, Nagao M, Kaziro Y, Itoh H; ''Activation of p38 mitogen-activated protein kinase by signaling through G protein-coupled receptors. Involvement of Gbetagamma and Galphaq/11 subunits.''; J Biol Chem, 1997 PubMed Europe PMC Scholia
Yoshimura K, Murakami M, Segawa A; ''Carbachol-induced [Ca2+]i increase, but not activation of protein kinase C, stimulates exocytosis in rat parotid acini.''; J Physiol, 2000 PubMed Europe PMC Scholia
Dhingra A, Lyubarsky A, Jiang M, Pugh EN Jr, Birnbaumer L, Sterling P, Vardi N; ''The light response of ON bipolar neurons requires G[alpha]o.''; J Neurosci, 2000 PubMed Europe PMC Scholia
Lee JR, Ha YJ, Kim HJ; ''Cutting edge: induced expression of a RhoA-specific guanine nucleotide exchange factor, p190RhoGEF, following CD40 stimulation and WEHI 231 B cell activation.''; J Immunol, 2003 PubMed Europe PMC Scholia
Kyriakis JM, Avruch J, Mizuta K, Tokushige M; ''Trypsin-catalyzed activation of aspartase.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Sung U, Jennings JL, Link AJ, Blakely RD; ''Proteomic analysis of human norepinephrine transporter complexes reveals associations with protein phosphatase 2A anchoring subunit and 14-3-3 proteins.''; Biochem Biophys Res Commun, 2005 PubMed Europe PMC Scholia
Tocco DJ, Breault GO, Zacchei AG, Steelman SL, Perrier CV; ''Physiological disposition and metabolism of 5-(2',4'-difluorophenyl)salicyclic acid, a new salicylate.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
Lo RK, Wong YH; ''Signal transducer and activator of transcription 3 activation by the delta-opioid receptor via Galpha14 involves multiple intermediates.''; Mol Pharmacol, 2004 PubMed Europe PMC Scholia
Harkness J; ''Why urinalysis?''; Cent Afr J Med, 1975 PubMed Europe PMC Scholia
Bakovic M, Waite K, Vance DE, Klimpel GR, Day KD, Lucas DO; ''Differential production of interferon and lymphotoxin by human tonsil lymphocytes.''; Cell Immunol, 1975 PubMed Europe PMC Scholia
Hahn MK, Blakely RD; ''Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders.''; Pharmacogenomics J, 2002 PubMed Europe PMC Scholia
Jelinek T, Dent P, Sturgill TW, Weber MJ; ''Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation.''; Mol Cell Biol, 1996 PubMed Europe PMC Scholia
Waskiewicz AJ, Johnson JC, Penn B, Mahalingam M, Kimball SR, Cooper JA, Murray J; ''The accreditation approach to infection control.''; Dimens Health Serv, 1975 PubMed Europe PMC Scholia
Schwarcz R, Coyle JT; ''Adenylate cyclase activity in chick retina.''; Gen Pharmacol, 1976 PubMed Europe PMC Scholia
Kamakura S, Oishi K, Yoshimatsu T, Nakafuku M, Masuyama N, Gotoh Y; ''Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling.''; Nat Cell Biol, 2004 PubMed Europe PMC Scholia
Chang RL, Zampaglione N, Lin C; ''Correlation of 14C-griseofulvin metabolism in rat liver microsomes, isolated perfused rat livers, and in rats with bile duct cannulas.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
van Horck FP, Ahmadian MR, Haeusler LC, Moolenaar WH, Kranenburg O; ''Characterization of p190RhoGEF, a RhoA-specific guanine nucleotide exchange factor that interacts with microtubules.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Edwards AS, Newton AC; ''Phosphorylation at conserved carboxyl-terminal hydrophobic motif regulates the catalytic and regulatory domains of protein kinase C.''; J Biol Chem, 1997 PubMed Europe PMC Scholia
MacKeigan JP, Collins TS, Ting JP, Eisenbrand G, Preussmann R; ''Nitrosation of phenacetin. Formation of N-nitroso-2-nitro-4-ethoxyacetanilide as an unstable product of the nitrosation in dilute aqueous-acidic solution.''; Arzneimittelforschung, 1975 PubMed Europe PMC Scholia
Miner LH, Schroeter S, Blakely RD, Sesack SR; ''Ultrastructural localization of the norepinephrine transporter in superficial and deep layers of the rat prelimbic prefrontal cortex and its spatial relationship to probable dopamine terminals.''; J Comp Neurol, 2003 PubMed Europe PMC Scholia
Berruti G; ''A novel rap1/B-Raf/14-3-3 theta protein complex is formed in vivo during the morphogenetic differentiation of postmeiotic male germ cells.''; Exp Cell Res, 2000 PubMed Europe PMC Scholia
Gao T, Toker A, Newton AC; ''The carboxyl terminus of protein kinase c provides a switch to regulate its interaction with the phosphoinositide-dependent kinase, PDK-1.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Wong WK, Ou XM, Chen K, Shih JC; ''Activation of human monoamine oxidase B gene expression by a protein kinase C MAPK signal transduction pathway involves c-Jun and Egr-1.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
Buchsbaum R, Telliez JB, Goonesekera S, Feig LA; ''The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium.''; Mol Cell Biol, 1996 PubMed Europe PMC Scholia
Smith JL, Collins I, Chandramouli GV, Butscher WG, Zaitseva E, Freebern WJ, Haggerty CM, Doseeva V, Gardner K, Kirksey ER, Pagels JF, Blem CR; ''The role of the tail in temperature regulation of the cotton rat, Sigmodon hispidus.''; Comp Biochem Physiol A Comp Physiol, 1975 PubMed Europe PMC Scholia
Dougalis A, Lees G, Ganellin CR; ''The sleep inducing brain lipid cis-oleamide (cOA) does not modulate serotonergic transmission in the CA1 pyramidal neurons of the hippocampus in vitro.''; Neuropharmacology, 2004 PubMed Europe PMC Scholia
Maier U, Babich A, Macrez N, Leopoldt D, Gierschik P, Illenberger D, Nurnberg B; ''Gbeta 5gamma 2 is a highly selective activator of phospholipid-dependent enzymes.''; J Biol Chem, 2000 PubMed Europe PMC Scholia
Lanfumey L, Hamon M; ''5-HT1 receptors.''; Curr Drug Targets CNS Neurol Disord, 2004 PubMed Europe PMC Scholia
Kalesnikoff J, Baur N, Leitges M, Hughes MR, Damen JE, Huber M, Krystal G; ''SHIP negatively regulates IgE + antigen-induced IL-6 production in mast cells by inhibiting NF-kappa B activity.''; J Immunol, 2002 PubMed Europe PMC Scholia
Höök M, Wasteson A, Oldberg A; ''A heparan sulfate-degrading endoglycosidase from rat liver tissue.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Papin C, Denouel-Galy A, Laugier D, Calothy G, Eychene A; ''Modulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-Raf.''; J Biol Chem, 1998 PubMed Europe PMC Scholia
Coxon PY, Rane MJ, Uriarte S, Powell DW, Singh S, Butt W, Chen Q, McLeish KR, Makar AB, McMartin KE, Palese M, Tephly TR; ''Formate assay in body fluids: application in methanol poisoning.''; Biochem Med, 1975 PubMed Europe PMC Scholia
Zippel R, Orecchia S, Sturani E, Martegani E; ''The brain specific Ras exchange factor CDC25 Mm: modulation of its activity through Gi-protein-mediated signals.''; Oncogene, 1996 PubMed Europe PMC Scholia
Peterson RN, Freund M; ''The inhibition of the motility of human spermatozoa by various pharmacologic agents.''; Biol Reprod, 1975 PubMed Europe PMC Scholia
Zhu CB, Hewlett WA, Feoktistov I, Biaggioni I, Blakely RD; ''Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation.''; Mol Pharmacol, 2004 PubMed Europe PMC Scholia
Job C, Lagnado L; ''Calcium and protein kinase C regulate the actin cytoskeleton in the synaptic terminal of retinal bipolar cells.''; J Cell Biol, 1998 PubMed Europe PMC Scholia
Hindley A, Kolch W; ''Extracellular signal regulated kinase (ERK)/mitogen activated protein kinase (MAPK)-independent functions of Raf kinases.''; J Cell Sci, 2002 PubMed Europe PMC Scholia
Ichiki T, Tokunou T, Fukuyama K, Iino N, Masuda S, Takeshita A, Talbot BG, Muir JG, Huber RE; ''Properties of a free and a solubilized form of bound alpha,alpha-trehalase purified from honey bee thorax.''; Can J Biochem, 1975 PubMed Europe PMC Scholia
Yosimichi G, Nakanishi T, Nishida T, Hattori T, Takano-Yamamoto T, Takigawa M; ''CTGF/Hcs24 induces chondrocyte differentiation through a p38 mitogen-activated protein kinase (p38MAPK), and proliferation through a p44/42 MAPK/extracellular-signal regulated kinase (ERK).''; Eur J Biochem, 2001 PubMed Europe PMC Scholia
Lim CP, Cao X; ''Regulation of Stat3 activation by MEK kinase 1.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Tamminga CA, Nemeroff CB, Blakely RD, Brady L, Carter CS, Davis KL, Dingledine R, Gorman JM, Grigoriadis DE, Henderson DC, B Innis RB, Killen J, Laughren TP, McDonald WM, M Murphy GM Jr, Paul SM, Rudorfer MV, Sausville E, Schatzberg AF, Scolnick EM, Suppes T; ''''; , PubMed Europe PMC Scholia
Titheradge MA, Coore HG; ''Hormonal regulation of liver mitochondrial pyruvate carrier in relation to gluconeogenesis and lipogenesis.''; FEBS Lett, 1976 PubMed Europe PMC Scholia
Bemski G; ''Study of the heat treatment of hemoglobin by means of spin labels.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Palmedo G, Hantschke M, Rütten A, Mentzel T, Hügel H, Flaig MJ, Yazdi AS, Sander CA, Kutzner H; ''The T1796A mutation of the BRAF gene is absent in Spitz nevi.''; J Cutan Pathol, 2004 PubMed Europe PMC Scholia
Ramos-Franco J, Fill M, Mignery GA; ''Isoform-specific function of single inositol 1,4,5-trisphosphate receptor channels.''; Biophys J, 1998 PubMed Europe PMC Scholia
Inoue H, Tateno M, Fujimura-Kamada K, Takaesu G, Adachi-Yamada T, Ninomiya-Tsuji J, Irie K, Nishida Y, Matsumoto K; ''A Drosophila MAPKKK, D-MEKK1, mediates stress responses through activation of p38 MAPK.''; EMBO J, 2001 PubMed Europe PMC Scholia
Mikoshiba K; ''[IP3 receptor, a Ca2+ oscilator--role of IP3 receptor in development and neural plasticity]''; Nippon Yakurigaku Zasshi, 2002 PubMed Europe PMC Scholia
Fothergill GA, Francis RJ, Hamilton TC, Osbond JM, Parkes MW; ''Bufuralol, a new beta-adrenoceptor blocking agent.''; Experientia, 1975 PubMed Europe PMC Scholia
Allen M, Svensson L, Roach M, Hambor J, McNeish J, Gabel CA, Tsukamoto I, Yoshinaga T, Sano S; ''Evidence for histidine as another functional group of delta-aminolevulinic acid dehydratase from beef liver.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Volpicelli-Daley LA, Hrabovska A, Duysen EG, Ferguson SM, Blakely RD, Lockridge O, Levey AI; ''Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice.''; Mol Pharmacol, 2003 PubMed Europe PMC Scholia
Simon SA, MacDonald RC, Bennett PB; ''Phase changes induced by cyclopropane of phosphatidylserine bilayers in the presence and absence of calcium.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Bagnato C, Igal RA; ''Overexpression of diacylglycerol acyltransferase-1 reduces phospholipid synthesis, proliferation, and invasiveness in simian virus 40-transformed human lung fibroblasts.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Russell M, Lange-Carter CA, Johnson GL; ''Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).''; J Biol Chem, 1995 PubMed Europe PMC Scholia
Hess A, Wijayanti N, Neuschäfer-Rube AP, Katz N, Kietzmann T, Immenschuh S; ''Phorbol ester-dependent activation of peroxiredoxin I gene expression via a protein kinase C, Ras, p38 mitogen-activated protein kinase signaling pathway.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Waris G, Turkson J, Hassanein T, Siddiqui A; ''Hepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replication.''; J Virol, 2005 PubMed Europe PMC Scholia
Mazei-Robison MS, Bowton E, Holy M, Schmudermaier M, Freissmuth M, Sitte HH, Galli A, Blakely RD; ''Anomalous dopamine release associated with a human dopamine transporter coding variant.''; J Neurosci, 2008 PubMed Europe PMC Scholia
Janknecht R, Hunter T; ''Convergence of MAP kinase pathways on the ternary complex factor Sap-1a.''; EMBO J, 1997 PubMed Europe PMC Scholia
Arozarena I, Matallanas D, Berciano MT, Sanz-Moreno V, Calvo F, Muñoz MT, Egea G, Lafarga M, Crespo P; ''Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors.''; Mol Cell Biol, 2004 PubMed Europe PMC Scholia
Hogan A, Shepherd L, Chabot J, Quenneville S, Prescott SM, Topham MK, Gee SH; ''Interaction of gamma 1-syntrophin with diacylglycerol kinase-zeta. Regulation of nuclear localization by PDZ interactions.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Tao FC, Tolloczko B, Mitchell CA, Powell WS, Martin JG; ''Inositol (1,4,5)trisphosphate metabolism and enhanced calcium mobilization in airway smooth muscle of hyperresponsive rats.''; Am J Respir Cell Mol Biol, 2000 PubMed Europe PMC Scholia
Azuma N, Akasaka N, Kito H, Ikeda M, Gahtan V, Sasajima T, Sumpio BE, Huet M; ''Factors affecting the molecular structure and the agglutinating ability of concanavalin A and other lectins.''; Eur J Biochem, 1975 PubMed Europe PMC Scholia
Blank JL, Gerwins P, Elliott EM, Sather S, Johnson GL; ''Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase.''; J Biol Chem, 1996 PubMed Europe PMC Scholia
Soroka V, Kiryushko D, Novitskaya V, Ronn LC, Poulsen FM, Holm A, Bock E, Berezin V, Steffin M; ''An oxygen dependent current in Aplysia neurons: an approach to the question of cellular hypoxic adaptation.''; Comp Biochem Physiol A Comp Physiol, 1975 PubMed Europe PMC Scholia
García KD, Shah T, García J; ''Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.''; Am J Physiol Cell Physiol, 2004 PubMed Europe PMC Scholia
Zhang J, Benovic JL, Sugai M, Wetzker R, Gout I, Rittenhouse SE; ''Sequestration of a G-protein beta gamma subunit or ADP-ribosylation of Rho can inhibit thrombin-induced activation of platelet phosphoinositide 3-kinases.''; J Biol Chem, 1995 PubMed Europe PMC Scholia
Guilbault B, Kay RJ; ''RasGRP1 sensitizes an immature B cell line to antigen receptor-induced apoptosis.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
Mochizuki N, Ohba Y, Kobayashi S, Otsuka N, Graybiel AM, Tanaka S, Matsuda M; ''Crk activation of JNK via C3G and R-Ras.''; J Biol Chem, 2000 PubMed Europe PMC Scholia
Roberts DM, Anderson AL, Hidaka M, Swetenburg RL, Patterson C, Stanford WL, Bautch VL; ''A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters.''; Mol Cell Biol, 2004 PubMed Europe PMC Scholia
Sung U, Jennings JL, Link AJ, Blakely RD; ''Proteomic analysis of human norepinephrine transporter complexes reveals associations with protein phosphatase 2A anchoring subunit and 14-3-3 proteins.''; Biochem Biophys Res Commun, 2005 PubMed Europe PMC Scholia
Krugmann S, Cooper MA, Williams DH, Hawkins PT, Stephens LR; ''Mechanism of the regulation of type IB phosphoinositide 3OH-kinase byG-protein betagamma subunits.''; Biochem J, 2002 PubMed Europe PMC Scholia
Price J; ''The dependence of tryptamine excretion on urinary pH.''; Clin Chim Acta, 1975 PubMed Europe PMC Scholia
Gubina E, Luo X, Kwon E, Sakamoto K, Shi YF, Mufson RA; ''betac cytokine receptor-induced stimulation of cAMP response element binding protein phosphorylation requires protein kinase C in myeloid cells: a novel cytokine signal transduction cascade.''; J Immunol, 2001 PubMed Europe PMC Scholia
Bartholeyns J, Peeters-Joris C, Baudhuin P; ''Hepatic nucleases. Extrahepatic origin and association of neutral liver ribonuclease with lysosomes.''; Eur J Biochem, 1975 PubMed Europe PMC Scholia
Jayanthi LD, Samuvel DJ, Blakely RD, Ramamoorthy S; ''Evidence for biphasic effects of protein kinase C on serotonin transporter function, endocytosis, and phosphorylation.''; Mol Pharmacol, 2005 PubMed Europe PMC Scholia
Hetman M, Kanning K, Cavanaugh JE, Xia Z, Tang BK, Inaba T, Kalow W; ''N-hydroxyamobarbital: the second major metabolite of amobarbital in man.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
Zhang BH, Guan KL; ''Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601.''; EMBO J, 2000 PubMed Europe PMC Scholia
Wiesmann UN, DiDonato S, Herschkowitz NN; ''Effect of chloroquine on cultured fibroblasts: release of lysosomal hydrolases and inhibition of their uptake.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Kaznacheyeva E, Lupu VD, Bezprozvanny I; ''Single-channel properties of inositol (1,4,5)-trisphosphate receptor heterologously expressed in HEK-293 cells.''; J Gen Physiol, 1998 PubMed Europe PMC Scholia
Caloca MJ, Zugaza JL, Bustelo XR; ''Exchange factors of the RasGRP family mediate Ras activation in the Golgi.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Sang N, Stiehl DP, Bohensky J, Leshchinsky I, Srinivas V, Caro J; ''MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Graham SM, Vojtek AB, Huff SY, Cox AD, Clark GJ, Cooper JA, Der CJ; ''TC21 causes transformation by Raf-independent signaling pathways.''; Mol Cell Biol, 1996 PubMed Europe PMC Scholia
Tokunou T, Ichiki T, Takeda K, Funakoshi Y, Iino N, Takeshita A, Fujii H, Nawa Y, Tsuchiya H, Matsuno K, Fukumoto T, Fukuda S, Kotani M; ''Effect of a single administration of testosterone on the immune response and lymphoid tissues in mice.''; Cell Immunol, 1975 PubMed Europe PMC Scholia
Schäfer C, Ross SE, Bragado MJ, Groblewski GE, Ernst SA, Williams JA; ''A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini.''; J Biol Chem, 1998 PubMed Europe PMC Scholia
Alexandru E, Vasilescu E, Ritli R, Popa I, Corneanu A; ''[3 cases of osteogenesis imperfecta of the Vrolik type]''; Rev Pediatr Obstet Ginecol Pediatr, 1977 PubMed Europe PMC Scholia
Mo Y, Ho W, Johnston K, Marmorstein R; ''Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex.''; J Mol Biol, 2001 PubMed Europe PMC Scholia
Williams JM, Owens WA, Turner GH, Saunders C, Dipace C, Blakely RD, France CP, Gore JC, Daws LC, Avison MJ, Galli A; ''Hypoinsulinemia regulates amphetamine-induced reverse transport of dopamine.''; PLoS Biol, 2007 PubMed Europe PMC Scholia
Hoard JL, Hoover DB, Mabe AM, Blakely RD, Feng N, Paolocci N; ''Cholinergic neurons of mouse intrinsic cardiac ganglia contain noradrenergic enzymes, norepinephrine transporters, and the neurotrophin receptors tropomyosin-related kinase A and p75.''; Neuroscience, 2008 PubMed Europe PMC Scholia
Engel K, Schultz H, Martin F, Kotlyarov A, Plath K, Hahn M, Heinemann U, Gaestel M, Mizuta K, Tokushige M; ''Trypsin-catalyzed activation of aspartase.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Hahn MK, Blakely RD; ''The functional impact of SLC6 transporter genetic variation.''; Annu Rev Pharmacol Toxicol, 2007 PubMed Europe PMC Scholia
Enslen H, Raingeaud J, Davis RJ; ''Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6.''; J Biol Chem, 1998 PubMed Europe PMC Scholia
Good DW, George T, Watts BA 3rd; ''Aldosterone potentiates 1,25-dihydroxyvitamin D3 action in renal thick ascending limb via a nongenomic, ERK-dependent pathway.''; Am J Physiol Cell Physiol, 2003 PubMed Europe PMC Scholia
Ishizuka T, Okajima F, Ishiwara M, Iizuka K, Ichimonji I, Kawata T, Tsukagoshi H, Dobashi K, Nakazawa T, Mori M, Alton KB, Patrick JE, Shaw C, McGuire JL; ''Comparative biotransformation of triflubazam in rats, dogs, and monkeys.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
Rybin VO, Xu X, Steinberg SF; ''Activated protein kinase C isoforms target to cardiomyocyte caveolae : stimulation of local protein phosphorylation.''; Circ Res, 1999 PubMed Europe PMC Scholia
Mak DO, Foskett JK; ''Effects of divalent cations on single-channel conduction properties of Xenopus IP3 receptor.''; Am J Physiol, 1998 PubMed Europe PMC Scholia
Enslen H, Brancho DM, Davis RJ; ''Molecular determinants that mediate selective activation of p38 MAP kinase isoforms.''; EMBO J, 2000 PubMed Europe PMC Scholia
Alessandrini A, Greulich H, Huang W, Erikson RL; ''Mek1 phosphorylation site mutants activate Raf-1 in NIH 3T3 cells.''; J Biol Chem, 1996 PubMed Europe PMC Scholia
Lin J, Weiss A; ''Identification of the minimal tyrosine residues required for linker for activation of T cell function.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Butts DA, Rokhsar DS; ''The information content of spontaneous retinal waves.''; J Neurosci, 2001 PubMed Europe PMC Scholia
Deacon K, Blank JL; ''Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo.''; J Biol Chem, 1997 PubMed Europe PMC Scholia
Siegel RC, Lian JB; ''LYSYL oxidase dependent synthesis of a collagen cross-link containing histidine.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Haq R, Brenton JD, Takahashi M, Finan D, Finkielsztein A, Damaraju S, Rottapel R, Zanke B, Chucklova IA, Sotnikova VS, Shchipakin VN, Evtodienko YV; ''[The fragmentation and reconstruction of the oligomycin-sensitive ATPase system of liver mitochondria]''; Biokhimiia, 1975 PubMed Europe PMC Scholia
Davison TF, Langslow DR; ''Changes in plasma glucose and liver glycogen following the administration of gluconeogenic precursors to the starving fowl.''; Comp Biochem Physiol A Comp Physiol, 1975 PubMed Europe PMC Scholia
Parys JB, Missiaen L, Smedt HD, Sienaert I, Casteels R; ''Mechanisms responsible for quantal Ca2+ release from inositol trisphosphate-sensitive calcium stores.''; Pflugers Arch, 1996 PubMed Europe PMC Scholia
Banihashemi B, Albert PR; ''Dopamine-D2S receptor inhibition of calcium influx, adenylyl cyclase, and mitogen-activated protein kinase in pituitary cells: distinct Galpha and Gbetagamma requirements.''; Mol Endocrinol, 2002 PubMed Europe PMC Scholia
Flowers LO, Subramaniam PS, Johnson HM; ''A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells.''; Oncogene, 2005 PubMed Europe PMC Scholia
Liu Y, Zhu M, Nishida K, Hirano T, Zhang W; ''An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response.''; J Exp Med, 2007 PubMed Europe PMC Scholia
Deak M, Clifton AD, Lucocq LM, Alessi DR; ''Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.''; EMBO J, 1998 PubMed Europe PMC Scholia
Gnesutta N, Ceriani M, Innocenti M, Mauri I, Zippel R, Sturani E, Borgonovo B, Berruti G, Martegani E; ''Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Brodie C, Steinhart R, Kazimirsky G, Rubinfeld H, Hyman T, Ayres JN, Hur GM, Toth A, Yang D, Garfield SH, Stone JC, Blumberg PM; ''PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters.''; Mol Pharmacol, 2004 PubMed Europe PMC Scholia
Pap EH, van den Berg PA, Borst JW, Visser AJ; ''The interaction between protein kinase C and lipid cofactors studied by simultaneous observation of lipid and protein fluorescence.''; J Biol Chem, 1995 PubMed Europe PMC Scholia
Coxon PY, Rane MJ, Uriarte S, Powell DW, Singh S, Butt W, Chen Q, McLeish KR, Anderson TR, Slotkin TA; ''Maturation of the adrenal medulla--IV. Effects of morphine.''; Biochem Pharmacol, 1975 PubMed Europe PMC Scholia
Vuong H, Patterson T, Shapiro P, Kalvakolanu DV, Wu R, Ma WY, Dong Z, Kleeberger SR, Reddy SP; ''Phorbol ester-induced expression of airway squamous cell differentiation marker, SPRR1B, is regulated by protein kinase Cdelta /Ras/MEKK1/MKK1-dependent/AP-1 signal transduction pathway.''; J Biol Chem, 2000 PubMed Europe PMC Scholia
Singh LP, Andy J, Anyamale V, Greene K, Alexander M, Crook ED; ''Hexosamine-induced fibronectin protein synthesis in mesangial cells is associated with increases in cAMP responsive element binding (CREB) phosphorylation and nuclear CREB: the involvement of protein kinases A and C.''; Diabetes, 2001 PubMed Europe PMC Scholia
Barnier JV, Papin C, Eychene A, Lecoq O, Calothy G; ''The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression.''; J Biol Chem, 1995 PubMed Europe PMC Scholia
Nakano A, Baines CP, Kim SO, Pelech SL, Downey JM, Cohen MV, Critz SD, Welinder BS; ''The crustacean cuticle--III. Composition of the individual layers in Cancer pagurus cuticle.''; Comp Biochem Physiol A Comp Physiol, 1975 PubMed Europe PMC Scholia
Rambaratsingh RA, Stone JC, Blumberg PM, Lorenzo PS; ''RasGRP1 represents a novel non-protein kinase C phorbol ester signaling pathway in mouse epidermal keratinocytes.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Sato M, Cordis GA, Maulik N, Das DK; ''SAPKs regulation of ischemic preconditioning.''; Am J Physiol Heart Circ Physiol, 2000 PubMed Europe PMC Scholia
Gosmanov AR, Wong JA, Thomason DB, Price J; ''The dependence of tryptamine excretion on urinary pH.''; Clin Chim Acta, 1975 PubMed Europe PMC Scholia
Pomerance M, Abdullah HB, Kamerji S, Correze C, Blondeau JP, PetitClerc C; ''Quantitative fractionation of alkaline phosphatase isoenzymes according to their thermostability.''; Clin Chem, 1976 PubMed Europe PMC Scholia
Reuther GW, Lambert QT, Rebhun JF, Caligiuri MA, Quilliam LA, Der CJ; ''RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
Wang L, Hayashi H, Kishi K, Huang L, Hagi A, Tamaoka K, Hawkins PT, Ebina Y; ''Gi-mediated translocation of GLUT4 is independent of p85/p110alpha and p110gamma phosphoinositide 3-kinases but might involve the activation of Akt kinase.''; Biochem J, 2000 PubMed Europe PMC Scholia
Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert ML, Quon MJ, Reed BC, Dikic I, Farese RV, Rosen RC; ''Ontogeny of homeothermy in Microtus pennsylvanicus and Octodon degus.''; Comp Biochem Physiol A Comp Physiol, 1975 PubMed Europe PMC Scholia
Monick MM, Carter AB, Flaherty DM, Peterson MW, Hunninghake GW; ''Protein kinase C zeta plays a central role in activation of the p42/44 mitogen-activated protein kinase by endotoxin in alveolar macrophages.''; J Immunol, 2000 PubMed Europe PMC Scholia
Shinkai M, Masuda T, Kariya K, Tamada M, Shirouzu M, Yokoyama S, Kataoka T; ''Difference in the mechanism of interaction of Raf-1 and B-Raf with H-Ras.''; Biochem Biophys Res Commun, 1996 PubMed Europe PMC Scholia
Durham PL, Sharma RV, Russo AF; ''Repression of the calcitonin gene-related peptide promoter by 5-HT1 receptor activation.''; J Neurosci, 1997 PubMed Europe PMC Scholia
Damjanoska KJ, Van de Kar LD, Kindel GH, Zhang Y, D'Souza DN, Garcia F, Battaglia G, Muma NA; ''Chronic fluoxetine differentially affects 5-hydroxytryptamine (2A) receptor signaling in frontal cortex, oxytocin- and corticotropin-releasing factor-containing neurons in rat paraventricular nucleus.''; J Pharmacol Exp Ther, 2003 PubMed Europe PMC Scholia
Smith RJ, Duerksen JD; ''Glycerol inhibition of purified and chromatin-associated mouse liver hepatoma RNA polymerase II activity.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, Müller M, Gaestel M, Resch K, Holtmann H; ''The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.''; EMBO J, 1999 PubMed Europe PMC Scholia
Karandikar M, Xu S, Cobb MH; ''MEKK1 binds raf-1 and the ERK2 cascade components.''; J Biol Chem, 2000 PubMed Europe PMC Scholia
Maizels ET, Mukherjee A, Sithanandam G, Peters CA, Cottom J, Mayo KE, Hunzicker-Dunn M, Wright P; ''Letter: Ocular reactions to beta-blocking drugs.''; Br Med J, 1975 PubMed Europe PMC Scholia
Nomura M, Kaji A, Ma WY, Zhong S, Liu G, Bowden GT, Miyamoto KI, Dong Z; ''Mitogen- and stress-activated protein kinase 1 mediates activation of Akt by ultraviolet B irradiation.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Platanias LC, Tohei N, Hosono T, Yoshinaga T, Himeno S, Saito R; ''Comparative studies of parasympatholytic drugs on stomach (double blind test) and analysis of relation between gastric form and tonus.''; Arzneimittelforschung, 1975 PubMed Europe PMC Scholia
Barberis L, Wary KK, Fiucci G, Liu F, Hirsch E, Brancaccio M, Altruda F, Tarone G, Giancotti FG; ''Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK.''; J Biol Chem, 2000 PubMed Europe PMC Scholia
Papin C, Denouel A, Calothy G, Eychene A; ''Identification of signalling proteins interacting with B-Raf in the yeast two-hybrid system.''; Oncogene, 1996 PubMed Europe PMC Scholia
Luo JH, Kahn S, O'Driscoll K, Weinstein IB; ''The regulatory domain of protein kinase C beta 1 contains phosphatidylserine- and phorbol ester-dependent calcium binding activity.''; J Biol Chem, 1993 PubMed Europe PMC Scholia
Greene EL, Houghton O, Collinsworth G, Garnovskaya MN, Nagai T, Sajjad T, Bheemanathini V, Grewal JS, Paul RV, Raymond JR; ''5-HT(2A) receptors stimulate mitogen-activated protein kinase via H(2)O(2) generation in rat renal mesangial cells.''; Am J Physiol Renal Physiol, 2000 PubMed Europe PMC Scholia
Browne DT, Kent SB; ''Formation of non-amidine products in the chemical modification of horse liver alcohol dehydrogenase with imido esters.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Song KS, Lee WJ, Chung KC, Koo JS, Yang EJ, Choi JY, Yoon JH, Mehendale HM, El-Bassiouni EA; ''Uptake and disposition of aldrin and dieldrin by isolated perfused rabbit lung.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
Dave KC, Dhattiwala AS; ''Adrenoreceptors of the guinea-pig urinary bladder.''; Br J Pharmacol, 1976 PubMed Europe PMC Scholia
Persons DL, Yazlovitskaya EM, Pelling JC, Hendrickson WA, Ward KB; ''Atomic models for the polypeptide backbones of myohemerythrin and hemerythrin.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Rubin BA, Voronkov LA, Zhivopistseva IV; ''[Adenine and pyridine nucleotides in forms of Verticillium dahliae Kleb. differing in pathogenicity]''; Dokl Akad Nauk SSSR, 1975 PubMed Europe PMC Scholia
Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z, Lessmann D, Schimz KL, Kurz G; ''D-glucose-6-phosphate dehydrogenase (Entner-Doudoroff enzyme) from Pseudomonas fluorescens. Purification, properties and regulation.''; Eur J Biochem, 1975 PubMed Europe PMC Scholia
Narita M, Ohnishi O, Nemoto M, Aoki T, Suzuki T; ''[The involvement of phosphoinositide 3-kinase (PI3-Kinase) and phospholipase C gamma (PLC gamma) pathway in the morphine-induced supraspinal antinociception in the mouse]''; Nihon Shinkei Seishin Yakurigaku Zasshi, 2001 PubMed Europe PMC Scholia
Yamauchi J, Kaziro Y, Itoh H; ''C-terminal mutation of G protein beta subunit affects differentially extracellular signal-regulated kinase and c-Jun N-terminal kinase pathways in human embryonal kidney 293 cells.''; J Biol Chem, 1997 PubMed Europe PMC Scholia
Cox DA, Watts SW, Cohen ML; ''Neomycin selectively inhibits 5-hydroxytryptamine-induced contraction in the guinea pig trachea.''; J Pharmacol Exp Ther, 1996 PubMed Europe PMC Scholia
Degousee N, Martindale J, Stefanski E, Cieslak M, Lindsay TF, Fish JE, Marsden PA, Thuerauf DJ, Glembotski CC, Rubin BB; ''MAP kinase kinase 6-p38 MAP kinase signaling cascade regulates cyclooxygenase-2 expression in cardiac myocytes in vitro and in vivo.''; Circ Res, 2003 PubMed Europe PMC Scholia
Chu CT, Levinthal DJ, Kulich SM, Chalovich EM, DeFranco DB; ''Oxidative neuronal injury. The dark side of ERK1/2.''; Eur J Biochem, 2004 PubMed Europe PMC Scholia
Avdi NJ, Winston BW, Russel M, Young SK, Johnson GL, Worthen GS; ''Activation of MEKK by formyl-methionyl-leucyl-phenylalanine in human neutrophils. Mapping pathways for mitogen-activated protein kinase activation.''; J Biol Chem, 1996 PubMed Europe PMC Scholia
Ni CW, Hsieh HJ, Chao YJ, Wang DL; ''Interleukin-6-induced JAK2/STAT3 signaling pathway in endothelial cells is suppressed by hemodynamic flow.''; Am J Physiol Cell Physiol, 2004 PubMed Europe PMC Scholia
Kawanabe Y, Hashimoto N, Masaki T; ''Role of phosphoinositide 3-kinase in the nonselective cation channel activation by endothelin-1/endothelinB receptor.''; Am J Physiol Cell Physiol, 2003 PubMed Europe PMC Scholia
Mitchell BK; ''Physiology of an ATP receptor in labellar sensilla of the tsetse fly Glossina morsitans morsitans Westw. (Diptera: Glossinidae).''; J Exp Biol, 1976 PubMed Europe PMC Scholia
Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazares A, Zamanillo D, Hunt T, Nebreda AR; ''A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins.''; Cell, 1994 PubMed Europe PMC Scholia
Chen KD, Chen LY, Huang HL, Lieu CH, Chang YN, Chang MD, Lai YK; ''Involvement of p38 mitogen-activated protein kinase signaling pathway in the rapid induction of the 78-kDa glucose-regulated protein in 9L rat brain tumor cells.''; J Biol Chem, 1998 PubMed Europe PMC Scholia
Iwata A, Maruyama M, Kanazawa I, Nukina N; ''alpha-Synuclein affects the MAPK pathway and accelerates cell death.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
Ferrand A, Kowalski-Chauvel A, Bertrand C, Escrieut C, Mathieu A, Portolan G, Pradayrol L, Fourmy D, Dufresne M, Seva C; ''A novel mechanism for JAK2 activation by a G protein-coupled receptor, the CCK2R: implication of this signaling pathway in pancreatic tumor models.''; J Biol Chem, 2005 PubMed Europe PMC Scholia
Lomri A, Lemonnier J, Delannoy P, Marie PJ; ''Increased expression of protein kinase Calpha, interleukin-1alpha, and RhoA guanosine 5'-triphosphatase in osteoblasts expressing the Ser252Trp fibroblast growth factor 2 receptor Apert mutation: identification by analysis of complementary DNA microarray.''; J Bone Miner Res, 2001 PubMed Europe PMC Scholia
Karim A, Hribar J, Aksamit W, Doherty M, Chinn LJ; ''Spironolactone metabolism in man studied by gas chromatography-mass spectrometry.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
Ogihara T, Watada H, Kanno R, Ikeda F, Nomiyama T, Tanaka Y, Nakao A, German MS, Kojima I, Kawamori R; ''p38 MAPK is involved in activin A- and hepatocyte growth factor-mediated expression of pro-endocrine gene neurogenin 3 in AR42J-B13 cells.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Sharp AH, Nucifora FC Jr, Blondel O, Sheppard CA, Zhang C, Snyder SH, Russell JT, Ryugo DK, Ross CA; ''Differential cellular expression of isoforms of inositol 1,4,5-triphosphate receptors in neurons and glia in brain.''; J Comp Neurol, 1999 PubMed Europe PMC Scholia
Carneiro AM, Airey DC, Thompson B, Zhu CB, Lu L, Chesler EJ, Erikson KM, Blakely RD; ''Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes.''; Proc Natl Acad Sci U S A, 2009 PubMed Europe PMC Scholia
Trushin SA, Pennington KN, Carmona EM, Asin S, Savoy DN, Billadeau DD, Paya CV; ''Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes.''; Mol Cell Biol, 2003 PubMed Europe PMC Scholia
Roberts EC, Shapiro PS, Nahreini TS, Pages G, Pouyssegur J, Ahn NG; ''Distinct cell cycle timing requirements for extracellular signal-regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis.''; Mol Cell Biol, 2002 PubMed Europe PMC Scholia
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR; ''PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo.''; J Biol Chem, 1995 PubMed Europe PMC Scholia
Oh-hora M, Johmura S, Hashimoto A, Hikida M, Kurosaki T; ''Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling.''; J Exp Med, 2003 PubMed Europe PMC Scholia
Greibrokk T, Hansen J, Knudsen R, Lam YK, Folkers K, Bowers CY; ''On the isolation of a prolactin inhibiting factor (hormone).''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Cyert MS, Chucklova IA, Sotnikova VS, Shchipakin VN, Evtodienko YV; ''[The fragmentation and reconstruction of the oligomycin-sensitive ATPase system of liver mitochondria]''; Biokhimiia, 1975 PubMed Europe PMC Scholia
''Report of the first hemispheric meeting on meningococcal disease.''; Bull Pan Am Health Organ, 1976 PubMed Europe PMC Scholia
Jonas BA, Privalsky ML; ''SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
Morgan MA, Dolp O, Reuter CW; ''[Kinetics and mechanism of action of horseradish peroxidase in the reaction of dioxyfumaric acid oxidation with atmospheric oxygen]''; Biokhimiia, 1975 PubMed Europe PMC Scholia
Funakoshi Y, Ichiki T, Takeda K, Tokuno T, Iino N, Takeshita A, Wall-Manning HJ; ''Problems with practolol.''; Drugs, 1975 PubMed Europe PMC Scholia
Knebel A, Morrice N, Cohen P; ''A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta.''; EMBO J, 2001 PubMed Europe PMC Scholia
Higashi H, Nakaya A, Tsutsumi R, Yokoyama K, Fujii Y, Ishikawa S, Higuchi M, Takahashi A, Kurashima Y, Teishikata Y, Tanaka S, Azuma T, Hatakeyama M; ''Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
Vanlingen S, Sipma H, De Smet P, Callewaert G, Missiaen L, De Smedt H, Parys JB; ''Modulation of inositol 1,4,5-trisphosphate binding to the various inositol 1,4,5-trisphosphate receptor isoforms by thimerosal and cyclic ADP-ribose.''; Biochem Pharmacol, 2001 PubMed Europe PMC Scholia
Li Z, Zhang G, Le Breton GC, Gao X, Malik AB, Du X; ''Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
De Smedt H, Parys JB; ''[Molecular and functional diversity of inositol triphosphate-induced Ca(2+) release]''; Verh K Acad Geneeskd Belg, 1995 PubMed Europe PMC Scholia
Fagan A; ''Government freezes administrators' salaries.''; Dimens Health Serv, 1976 PubMed Europe PMC Scholia
Hu MC, Wang YP, Mikhail A, Qiu WR, Tan TH, Sanchez G, Alderete JF; ''The effect of host adrenalectomy on the physiology of Trypanosoma rhodesiense.''; Comp Biochem Physiol A Comp Physiol, 1975 PubMed Europe PMC Scholia
Hassler M, Richmond TJ; ''The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex.''; EMBO J, 2001 PubMed Europe PMC Scholia
Toki S, Kawasaki H, Tashiro N, Housman DE, Graybiel AM; ''Guanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neurons.''; J Comp Neurol, 2001 PubMed Europe PMC Scholia
Cameron AM, Steiner JP, Sabatini DM, Kaplin AI, Walensky LD, Snyder SH; ''Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux.''; Proc Natl Acad Sci U S A, 1995 PubMed Europe PMC Scholia
Miner LH, Jedema HP, Moore FW, Blakely RD, Grace AA, Sesack SR; ''Chronic stress increases the plasmalemmal distribution of the norepinephrine transporter and the coexpression of tyrosine hydroxylase in norepinephrine axons in the prefrontal cortex.''; J Neurosci, 2006 PubMed Europe PMC Scholia
Brodie C, Steinhart R, Kazimirsky G, Rubinfeld H, Hyman T, Ayres JN, Hur GM, Toth A, Yang D, Garfield SH, Stone JC, Blumberg PM; ''PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters.''; Mol Pharmacol, 2004 PubMed Europe PMC Scholia
Hahn MK, Robertson D, Blakely RD; ''A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters.''; J Neurosci, 2003 PubMed Europe PMC Scholia
Kawanabe Y, Hashimoto N, Masaki T; ''Effects of phosphoinositide 3-kinase on the endothelin-1-induced activation of voltage-independent Ca(2+) channels and mitogenesis in Chinese hamster ovary cells stably expressing endothelin(a) receptor.''; Mol Pharmacol, 2002 PubMed Europe PMC Scholia
Sung U, Blakely RD; ''Calcium-dependent interactions of the human norepinephrine transporter with syntaxin 1A.''; Mol Cell Neurosci, 2007 PubMed Europe PMC Scholia
Gold MR, Scheid MP, Santos L, Dang-Lawson M, Roth RA, Matsuuchi L, Duronio V, Krebs DL; ''The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase.''; J Immunol, 1999 PubMed Europe PMC Scholia
Lova P, Campus F, Lombardi R, Cattaneo M, Sinigaglia F, Balduini C, Torti M; ''Contribution of protease-activated receptors 1 and 4 and glycoprotein Ib-IX-V in the G(i)-independent activation of platelet Rap1B by thrombin.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
Biondi RM, Komander D, Thomas CC, Lizcano JM, Deak M, Alessi DR, van Aalten DM; ''High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site.''; EMBO J, 2002 PubMed Europe PMC Scholia
Kim JS, Chang JH, Yu HK, Ahn JH, Yum JS, Lee SK, Jung KH, Park DH, Yoon Y, Byun SM, Chung SI, Durham BH; ''Spectrophotometric end-point method for assay of serum cystyl-aminopeptidase in pregnancy.''; Clin Chem, 1976 PubMed Europe PMC Scholia
Meyer-ter-Vehn T, Covacci A, Kist M, Pahl HL, Agar NS, Stephens T; ''Reduced glutathione--a comparative study of erythrocytes from various species of marsupials in Australia.''; Comp Biochem Physiol A Comp Physiol, 1975 PubMed Europe PMC Scholia
Belanger LF, Roy S, Tremblay M, Brott B, Steff AM, Mourad W, Hugo P, Erikson R, Charron J, Jayaram HN, Cooney DA, Ryan JA, Neil G, Dion RL, Bono VH; ''L-[alphaS, 5S]-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (NSC-163501): a new amino acid antibiotic with the properties of an antagonist of L-glutamine.''; Cancer Chemother Rep, 1975 PubMed Europe PMC Scholia
Tan Y, Rouse J, Zhang A, Cariati S, Cohen P, Comb MJ, Wiesmann UN, DiDonato S, Herschkowitz NN; ''Effect of chloroquine on cultured fibroblasts: release of lysosomal hydrolases and inhibition of their uptake.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Chu CT, Levinthal DJ, Kulich SM, Chalovich EM, DeFranco DB; ''Oxidative neuronal injury. The dark side of ERK1/2.''; Eur J Biochem, 2004 PubMed Europe PMC Scholia
Liprando LA, Miner LH, Blakely RD, Lewis DA, Sesack SR; ''Ultrastructural interactions between terminals expressing the norepinephrine transporter and dopamine neurons in the rat and monkey ventral tegmental area.''; Synapse, 2004 PubMed Europe PMC Scholia
Matsubara T, Kimura T, Kuroda T, Hirohata K; ''Signal transduction in glycosaminoglycan (GAG) synthesis by cultured chondrocytes and its inhibition by inflammatory cell-derived hydrogen peroxide.''; Br J Rheumatol, 1992 PubMed Europe PMC Scholia
Katagiri K, Shimonaka M, Kinashi T; ''Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
Andersson TP, Sköld HN, Svensson SP; ''Phosphoinositide 3-kinase is involved in Xenopus and Labrus melanophore aggregation.''; Cell Signal, 2003 PubMed Europe PMC Scholia
Dumaz N, Marais R; ''Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Raingeaud J, Whitmarsh AJ, Barrett T, Dérijard B, Davis RJ; ''MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway.''; Mol Cell Biol, 1996 PubMed Europe PMC Scholia
Okada T, Masuda T, Shinkai M, Kariya K, Kataoka T; ''Post-translational modification of H-Ras is required for activation of, but not for association with, B-Raf.''; J Biol Chem, 1996 PubMed Europe PMC Scholia
Castle AG, Marsh JC, Crawford N; ''Evidence against tubulin--actin homology.''; FEBS Lett, 1976 PubMed Europe PMC Scholia
Boyarsky BK, Haque W, Rouleau MR, Hirschfeld RM; ''Sexual functioning in depressed outpatients taking mirtazapine.''; Depress Anxiety, 1999 PubMed Europe PMC Scholia
Marquet A, Nieto M, Diaz-Mauriño T; ''Membrane-bound DD-carboxypeptidase and transpeptidase activities from Bacillus megaterium KM at pH 7. General properties, substrate specificity and inhibition by beta-lactam antibiotics.''; Eur J Biochem, 1976 PubMed Europe PMC Scholia
Paine E, Palmantier R, Akiyama SK, Olden K, Roberts JD, Snyder WD, Fox SW; ''A model for the origin of stable protocells in a primitive alkaline ocean.''; Biosystems, 1975 PubMed Europe PMC Scholia
Nair VD, Sealfon SC; ''Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
Caivano M, Cohen P, Juchau MR, Namkung MJ, Berry DL, Zachariah PK; ''Oxidative biotransformation of 2-acetylaminofluorene in fetal and placental tissues of humans and monkeys. Correlations with aryl hydrocarbon hydroxylase activities.''; Drug Metab Dispos, 1975 PubMed Europe PMC Scholia
Della Rocca GJ, van Biesen T, Daaka Y, Luttrell DK, Luttrell LM, Lefkowitz RJ, Yoshida M, Sone N, Hirata H, Kagawa Y; ''ATP synthesis catalyzed by purified DCCD-sensitive ATPase incorporated into reconstituted purple membrane vesicles.''; Biochem Biophys Res Commun, 1975 PubMed Europe PMC Scholia
Levy RA, Nystrom RA, Nadelhaft I; ''Geographical and electrical features of large neurons in Limulus abdominal ganglia.''; Comp Biochem Physiol A Comp Physiol, 1975 PubMed Europe PMC Scholia
Huber-Lang MS, Younkin EM, Sarma JV, McGuire SR, Lu KT, Guo RF, Padgaonkar VA, Curnutte JT, Erickson R, Ward PA; ''''; , PubMed Europe PMC Scholia
Imre S, Szilágyi T, Tóth S; ''Effect of osmotic pressure, ionic strength and dibutyryl cyclic adenosine monophosphate on the adhesion of hen erythrocytes.''; Blut, 1976 PubMed Europe PMC Scholia
Takei K, Shin RM, Inoue T, Kato K, Mikoshiba K; ''Regulation of nerve growth mediated by inositol 1,4,5-trisphosphate receptors in growth cones.''; Science, 1998 PubMed Europe PMC Scholia
Carneiro AM, Cook EH, Murphy DL, Blakely RD; ''Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans.''; J Clin Invest, 2008 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
136011	view	14:34, 8 December 2024	Eweitz	Fix graphics discrepancy between PathVisio and Kaavio / Pvjs
136010	view	13:18, 8 December 2024	Eweitz	Clear cache to update board dimensions
136009	view	13:16, 8 December 2024	Eweitz	Economize layout
136008	view	03:50, 8 December 2024	Eweitz	Refine legend
136007	view	03:47, 8 December 2024	Eweitz	Increase font size, for readability
136006	view	03:39, 8 December 2024	Eweitz	Refine legend
136005	view	03:33, 8 December 2024	Eweitz	Economize layout
136004	view	03:32, 8 December 2024	Eweitz	Economize layout
125764	view	14:31, 9 March 2023	DeSl	Added rhea ID and ref. for PI3K interaction
125763	view	14:27, 9 March 2023	DeSl	Fixed PI3K enzyme conversion
125656	view	15:59, 6 March 2023	DeSl	Integrated description from WP733
125655	view	15:58, 6 March 2023	DeSl	Integrated WP733
125651	view	15:51, 6 March 2023	DeSl	Added two annotations
125650	view	15:47, 6 March 2023	DeSl	Converted (in)direct regulation to MIM-stimulation
125649	view	15:43, 6 March 2023	DeSl	Vretical layout, converted arrow to MIM-conversion
125648	view	15:41, 6 March 2023	DeSl	Changed layout
125647	view	15:40, 6 March 2023	DeSl	Converted some arrows to specific MIM-types
125646	view	15:35, 6 March 2023	DeSl	Updating to current color scheme
125633	view	02:01, 6 March 2023	AlexanderPico	Modified description
125272	view	15:34, 31 January 2023	Egonw	Fixed two more references
125271	view	15:22, 31 January 2023	Egonw	Fixed a reference
120570	view	01:00, 17 December 2021	Khanspers	updated lit refs
120569	view	00:58, 17 December 2021	Khanspers	updated lit refs
120568	view	00:45, 17 December 2021	Khanspers	fixed literature references to remove weird characters
117823	view	15:06, 22 May 2021	Eweitz	Modified title
106177	view	12:07, 16 August 2019	MaintBot	HMDB identifier normalization
102357	view	19:43, 20 December 2018	Fehrhart	fixed unconnected lines
102125	view	17:03, 1 December 2018	Egonw	Removed whitespace in PubMed identifiers.
74511	view	05:59, 27 April 2014	Egonw	Last batch of PubMed ID fixes.
74501	view	17:12, 26 April 2014	Egonw	More PubMed ID fixes.
74499	view	16:58, 26 April 2014	Egonw	Fixed PubMed IDs.
73767	view	00:49, 22 February 2014	MaintBot	updating schema
49735	view	09:04, 25 July 2012	Andra	RDF Tidy
49638	view	10:31, 23 July 2012	Andra	RDF Tidy
49633	view	09:57, 23 July 2012	Andra	RDF Tidy
49625	view	09:24, 23 July 2012	Andra	RDF Tidy
49624	view	09:22, 23 July 2012	Andra	RDF Tidy
49621	view	08:51, 23 July 2012	Andra	RDF Tidy
49580	view	07:14, 21 July 2012	Andra	RDF Tidy
49556	view	19:33, 20 July 2012	Andra	RDF tidy
49540	view	09:59, 20 July 2012	Andra	Corrected references
49539	view	09:48, 20 July 2012	Andra	Corrected a erroneous pubmed reference
49534	view	09:06, 20 July 2012	Andra	Corrected a pubmed error
46093	view	03:28, 15 December 2011	AlexanderPico	converted more hugo to hgnc
45025	view	18:43, 6 October 2011	Thomas	Ontology Term : 'serotonin signaling pathway' added !
41105	view	23:22, 1 March 2011	MaintBot	Removed redundant pathway information and comments
39767	view	07:54, 17 January 2011	AlexanderPico
34469	view	18:32, 10 December 2009	MaintBot	Automatic update of empty xrefs
33424	view	14:53, 30 November 2009	MaintBot	Removed group label
33185	view	17:56, 5 November 2009	Khanspers	Modified categories

External references

DataNodes

View all...

Name	Type	Database reference	Comment
1,2-Diacetin	Metabolite	102-62-5 (CAS)	diacylglycerol
1,4,5-Insp3	Metabolite	85166-31-0 (CAS)
BRAF	GeneProduct	673 (Entrez Gene)	v-raf murine sarcoma viral oncogene homolog B1
CALCIUM	Metabolite	7440-70-2 (CAS)
CREB1	GeneProduct	1385 (Entrez Gene)	cAMP response element-binding protein 1
ELK1	GeneProduct	2002 (Entrez Gene)	ELK1, member of ETS oncogene family
ELK4	GeneProduct	2005 (Entrez Gene)	ETS domain-containing protein Elk-4 (SRF accessory protein 1)
FOS	GeneProduct	2353 (Entrez Gene)	proto-oncogene protein c-fos
GNAI1	Protein	2770 (Entrez Gene)
GNAI2	Protein	2771 (Entrez Gene)
GNAI3	Protein	2773 (Entrez Gene)
GNAO1	Protein	2775 (Entrez Gene)
GNAQ	GeneProduct	2776 (Entrez Gene)	guanine nucleotide binding protein, alpha q polypeptide
Gb/g	Complex
HTR1A	Protein	3350 (Entrez Gene)
HTR1B	Protein	3351 (Entrez Gene)
HTR1D	Protein	3352 (Entrez Gene)
HTR1E	Protein	3354 (Entrez Gene)
HTR1F	Protein	3355 (Entrez Gene)
HTR2A	GeneProduct	3356 (Entrez Gene)	5-hydroxytryptamine (serotonin) receptor 2A
ITPR1	GeneProduct	3708 (Entrez Gene)	inositol 1,4,5-triphosphate receptor 1
JAK2	GeneProduct	3717 (Entrez Gene)	Janus kinase 2
MAP2K1	GeneProduct	5604 (Entrez Gene)	mitogen activated protein kinase kinase 1
MAP2K2	GeneProduct	5605 (Entrez Gene)	mitogen activated protein kinase kinase 2
MAP2K3	GeneProduct	5606 (Entrez Gene)	mitogen activated protein kinase kinase 3
MAP2K6	GeneProduct	5608 (Entrez Gene)	mitogen activated protein kinase kinase 6
MAP3K1	GeneProduct	4214 (Entrez Gene)	mitogen activated protein kinase kinase kinase 1
MAPK14	GeneProduct	1432 (Entrez Gene)	mitogen activated protein kinase 14
MAPK1	GeneProduct	MAPK1 (HGNC)	mitogen activated protein kinase 1
MAPK3	GeneProduct	5595 (Entrez Gene)	mitogen activated protein kinase 3
MAPKAPK2	GeneProduct	9261 (Entrez Gene)	mitogen activated protein kinase 3
MAPKAPK3	GeneProduct	7867 (Entrez Gene)	mitogen-activated protein kinase-activated protein kinase 3
PDPK1	GeneProduct	5170 (Entrez Gene)	3-phosphoinositide dependent protein kinase-1
PI3K	GeneProduct	5290 (Entrez Gene)	phosphatidylinositol 3-kinase
PKC	GeneProduct	50818 (Entrez Gene)	protein kinase C
PLC	GeneProduct	3.1.4.11 (Enzyme Nomenclature)	phospholipase C
PtdIns2P	Metabolite	CHEBI:58456 (ChEBI)	phosphatidylinositol 4,5-diphosphate
PtdIns3P	Metabolite	57836 (ChEBI)	phosphatidylinositol 3,4,5-triphosphate
RAP1A	GeneProduct	5906 (Entrez Gene)	RAS-related protein-1a
RASGRF1	GeneProduct	5923 (Entrez Gene)	RAS protein-specific guanine nucleotide-releasing factor 1
RASGRP1	GeneProduct	10125 (Entrez Gene)	RAS guanyl releasing protein 1
RHOA	GeneProduct	387 (Entrez Gene)	ras homolog gene family, member A
RPS6K	GeneProduct		Functional Class RPS6K (ribosomal protein S6 kinase)
RPS6KA5	GeneProduct	9252 (Entrez Gene)	ribosomal protein S6 kinase, polypeptide 5
Ras	GeneProduct		RAS oncogene homolog
SRF	GeneProduct	6722 (Entrez Gene)	serum response factor
STAT3	GeneProduct	6774 (Entrez Gene)	signal transducer and activator of transcription
Serotonin	Metabolite	HMDB0000259 (HMDB)

Annotated Interactions

Source	Target	Type	Database reference	Comment
PtdIns2P	PtdIns3P	mim-conversion	21293 (Rhea)

Serotonin HTR1 group and FOS pathway (Homo sapiens)

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