Hepatocyte growth factor receptor signaling (Danio rerio)
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RHO
pathway
P
RAC1
pathway
Changes in Cytoskeleton
and Cell mobility
Anoikis
P
Transcription
of Cox2
Cytoplasm
Extracellular
AKT Pathway
Right Click for Comments
AP-1
Trancription
Transcription
CDC42
pathway
P
Actin
map2k1
LOC567895
dock1
ptk2bb
ptk2bb
stat3
SOS1
rap1a
rasa1
src
zgc:172250
mapk1
CH211-127H20.2
hgfa
crk
ITGB1
pak1
MAP4K1
HRAS
mapk3
ptpn11
pxn
gab1
LOC561737
zgc:172209
ptk2.1
Met
src
rap1b
grb2
ptenb
fos
jun
raf1
pxn
LOC570868
crkl
ptk2.1
Description
No description
Comments
GenMAPP remarks
Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP313(r21339)
with a 86% conversion rate.
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Organ SL, Tsao MS; ''An overview of the c-MET signaling pathway.''; Ther Adv Med Oncol, 2011
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
118749
view
10:59, 1 June 2021
DeSl
Ontology Term : 'Rho/Rac/Cdc42 mediated signaling pathway' added !
118748
view
10:59, 1 June 2021
DeSl
Ontology Term : 'hepatocyte' added !
118747
view
10:59, 1 June 2021
DeSl
Removed textlabel
118746
view
10:58, 1 June 2021
DeSl
Converted "P" to states
118745
view
10:57, 1 June 2021
DeSl
Converted ReceptorSquare to MIM binding with lit. ref
118744
view
10:56, 1 June 2021
DeSl
Added description from WP313
116905
view
11:35, 15 May 2021
Eweitz
Modified title
109424
view
07:59, 17 March 2020
L Dupuis
Changed interactions to graphical lines representing the cell membrane
68677
view
05:35, 6 July 2013
MaintBot
Updated to 2013 gpml schema
67646
view
11:44, 26 June 2013
Ddigles
Ontology Term : 'scatter factor/hepatocyte growth factor signaling pathway' added !
40850
view
22:19, 1 March 2011
MaintBot
Removed redundant pathway information and comments
34232
view
21:38, 9 December 2009
MaintBot
Automatic update of empty xrefs
32433
view
17:14, 15 August 2009
MaintBot
Fixed text labels
32102
view
13:45, 14 August 2009
MaintBot
Fixed group labels
31454
view
21:12, 13 August 2009
MaintBot
Fixed text labels
31079
view
01:33, 30 July 2009
MaintBot
Converted from Homo sapiens
21614
view
11:32, 14 November 2008
MaintBot
[[Pathway:Danio rerio:Signaling of Hepatocyte Growth Factor Receptor Biocarta]] moved to [[Pathway:WP444]]: Moved to stable identifier
12024
view
08:44, 15 May 2008
MaintBot
Added to category $category
12022
view
08:44, 15 May 2008
MaintBot
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
CH211-127H20.2
GeneProduct
558635 (Entrez Gene)
HRAS
GeneProduct
550286 (Entrez Gene)
ITGB1
GeneProduct
LOC561737
GeneProduct
561737 (Entrez Gene)
LOC567895
GeneProduct
567895 (Entrez Gene)
LOC570868
GeneProduct
570868 (Entrez Gene)
MAP4K1
GeneProduct
Met
GeneProduct
0 (Entrez Gene)
SOS1
GeneProduct
Son of sevenless homolog 1 (Drosophila) (predicted)
crk
GeneProduct
445234 (Entrez Gene)
crkl
GeneProduct
556443 (Entrez Gene)
dock1
GeneProduct
572187 (Entrez Gene)
Interim Symbol: Dock1 predicted and Name: dedicator of cyto-kinesis 1 (predicted)
fos
GeneProduct
394198 (Entrez Gene)
gab1
GeneProduct
406666 (Entrez Gene)
grb2
GeneProduct
406308 (Entrez Gene)
hgfa
GeneProduct
493781 (Entrez Gene)
jun
GeneProduct
335916 (Entrez Gene)
map2k1
GeneProduct
406728 (Entrez Gene)
mapk1
GeneProduct
360144 (Entrez Gene)
mapk3
GeneProduct
399480 (Entrez Gene)
pak1
GeneProduct
373103 (Entrez Gene)
ptenb
GeneProduct
368415 (Entrez Gene)
ptk2.1
GeneProduct
142986 (Entrez Gene)
ptk2bb
GeneProduct
245950 (Entrez Gene)
ptpn11
GeneProduct
333979 (Entrez Gene)
pxn
GeneProduct
399546 (Entrez Gene)
raf1
GeneProduct
30716 (Entrez Gene)
rap1a
GeneProduct
415242 (Entrez Gene)
rap1b
GeneProduct
321107 (Entrez Gene)
rasa1
GeneProduct
100002155 (Entrez Gene)
src
GeneProduct
325084 (Entrez Gene)
stat3
GeneProduct
30767 (Entrez Gene)
zgc:172209
GeneProduct
562720 (Entrez Gene)
zgc:172250
GeneProduct
100002225 (Entrez Gene)
Annotated Interactions
No annotated interactions
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DataNodes
Annotated Interactions
No annotated interactions