Pilocytic astrocytoma (Homo sapiens)

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RAF1ERKNUCLEUSCYTOPLASAMPTPN11TRANSFER FACTORGrb2Cytoplasmic targetsSOSNF1Cell growth,survival,motilityBRAFMEKRTKRas:GTPRas:GDP


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. McKay MM, Morrison DK; ''Integrating signals from RTKs to ERK/MAPK.''; Oncogene, 2007 PubMed Europe PMC Scholia
  2. Jones DT, Kocialkowski S, Liu L, Pearson DM, Ichimura K, Collins VP; ''Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma.''; Oncogene, 2009 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
129826view23:09, 22 May 2024EweitzPoint RTK to gene family
128531view15:25, 11 February 2024EweitzOntology Term : 'cancer' added !
128530view15:23, 11 February 2024EweitzEconomize layout, fix typos, increase font size for readability
112071view10:16, 18 September 2020DeSlConnected last unconnected interaction.
111811view17:25, 8 September 2020EgonwFixed another identifier.
111810view17:24, 8 September 2020EgonwFixed an Ensembl identifier
111781view13:27, 7 September 2020DeSlModified description
111780view13:26, 7 September 2020DeSlUpdated interations, added IDs for ERK and MEK, added mutation info from paper
111779view13:15, 7 September 2020DeSlAdded IDs for BRAF and RAF1
111778view13:06, 7 September 2020DeSlStarted updating interaction types + IDs RAS
111777view12:44, 7 September 2020DeSlRemoved last modified item.
111776view12:43, 7 September 2020DeSlUpdate RTK EC number (without space)
111775view12:42, 7 September 2020DeSlOntology Term : 'mitogen activated protein kinase signaling pathway' added !
111774view12:42, 7 September 2020DeSlOntology Term : 'pilocytic astrocytoma' added !
111773view12:41, 7 September 2020DeSlOntology Term : 'astrocytoma' added !
111772view12:41, 7 September 2020DeSlAdded ref for PW, updated description.
109364view14:09, 16 March 2020L DupuisConnected line
106707view13:13, 17 September 2019MaintBotHMDB identifier normalization
102358view19:49, 20 December 2018Fehrhartfixed some graphical issues
94224view22:42, 25 August 2017DeSlChanged RTK metabolite node to protein node, added ID for this node.
74520view21:34, 28 April 2014KhanspersModified title
69013view17:47, 8 July 2013MaintBotUpdated to 2013 gpml schema
67597view11:31, 26 June 2013DdiglesOntology Term : 'glioma pathway' added !
59199view19:14, 22 February 2013MaintBotUpdated Ensembl and UniProt data source
54370view15:01, 28 November 2012MaintBotremoved mim-gap end type
53138view02:00, 30 October 2012MaintBotModified categories
49791view10:47, 26 July 2012DeviModified description
49790view06:50, 26 July 2012DeviPilocytic astrocytoma
49771view19:24, 25 July 2012MaintBotconnected nodes to database object
49739view10:32, 25 July 2012DeviNew pathway

External references

DataNodes

NameTypeDatabase referenceComment
RTKMetabolite
Ras:GDPMetabolite
Ras:GTPMetabolite

Annotated Interactions

No annotated interactions

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