Pilocytic astrocytoma (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. McKay MM, Morrison DK; ''Integrating signals from RTKs to ERK/MAPK.''; Oncogene, 2007 PubMed Europe PMC Scholia
2. Jones DT, Kocialkowski S, Liu L, Pearson DM, Ichimura K, Collins VP; ''Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma.''; Oncogene, 2009 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	129826	view	23:09, 22 May 2024	Eweitz	Point RTK to gene family
	128531	view	15:25, 11 February 2024	Eweitz	Ontology Term : 'cancer' added !
	128530	view	15:23, 11 February 2024	Eweitz	Economize layout, fix typos, increase font size for readability
	112071	view	10:16, 18 September 2020	DeSl	Connected last unconnected interaction.
	111811	view	17:25, 8 September 2020	Egonw	Fixed another identifier.
	111810	view	17:24, 8 September 2020	Egonw	Fixed an Ensembl identifier
	111781	view	13:27, 7 September 2020	DeSl	Modified description
	111780	view	13:26, 7 September 2020	DeSl	Updated interations, added IDs for ERK and MEK, added mutation info from paper
	111779	view	13:15, 7 September 2020	DeSl	Added IDs for BRAF and RAF1
	111778	view	13:06, 7 September 2020	DeSl	Started updating interaction types + IDs RAS
	111777	view	12:44, 7 September 2020	DeSl	Removed last modified item.
	111776	view	12:43, 7 September 2020	DeSl	Update RTK EC number (without space)
	111775	view	12:42, 7 September 2020	DeSl	Ontology Term : 'mitogen activated protein kinase signaling pathway' added !
	111774	view	12:42, 7 September 2020	DeSl	Ontology Term : 'pilocytic astrocytoma' added !
	111773	view	12:41, 7 September 2020	DeSl	Ontology Term : 'astrocytoma' added !
	111772	view	12:41, 7 September 2020	DeSl	Added ref for PW, updated description.
	109364	view	14:09, 16 March 2020	L Dupuis	Connected line
	106707	view	13:13, 17 September 2019	MaintBot	HMDB identifier normalization
	102358	view	19:49, 20 December 2018	Fehrhart	fixed some graphical issues
	94224	view	22:42, 25 August 2017	DeSl	Changed RTK metabolite node to protein node, added ID for this node.
	74520	view	21:34, 28 April 2014	Khanspers	Modified title
	69013	view	17:47, 8 July 2013	MaintBot	Updated to 2013 gpml schema
	67597	view	11:31, 26 June 2013	Ddigles	Ontology Term : 'glioma pathway' added !
	59199	view	19:14, 22 February 2013	MaintBot	Updated Ensembl and UniProt data source
	54370	view	15:01, 28 November 2012	MaintBot	removed mim-gap end type
	53138	view	02:00, 30 October 2012	MaintBot	Modified categories
	49791	view	10:47, 26 July 2012	Devi	Modified description
	49790	view	06:50, 26 July 2012	Devi	Pilocytic astrocytoma
	49771	view	19:24, 25 July 2012	MaintBot	connected nodes to database object
	49739	view	10:32, 25 July 2012	Devi	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
GRB2	GeneProduct	ENSG00000177885 (Ensembl Human)
NF1	GeneProduct	ENSG00000196712 (Ensembl Human)
PTPN11	GeneProduct	ENSG00000179295 (Ensembl Human)
RAS:GDP	Metabolite	HMDB00960 (HMDB)
RAS:GTP	Metabolite	HMDB01440 (HMDB)
RTK	Metabolite
SOS1	GeneProduct	ENSG00000115904 (Ensembl Human)

Annotated Interactions

No annotated interactions