Proteasome degradation (Caenorhabditis elegans)

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Proteins to be DegradedUbiquitin/ProteinAMP Ubiquitin/E1 ComplexBeta subunitsUbiquitin/E2 ComplexE3/ProteinPresentation by MHC class 1ATPDegrades only PeptidesAlpha subunitsProteasome 26 SCytosolic ProteinsCatalytic Core (p45)Intact ProteinsLid subunits20S Complex(PA700) (ATP dependent)Oxidatively DamagedUnfolds and DegradesActivators ofProteasome 20Sp45 ATPase Subunitpbs-6rpn-5ubq-1pas-7rpn-8R08C7.3IFNGUBE2D1UBE1LPSMD5rpn-3HLA-Ehis-35HLA-Jpbs-5HLA-Crpt-6rpn-9UBE2D2endopeptidasePSME1Y66D12A.9ATPasePSMB4peptidaseHLA-Arpt-4let-70glycotransferasePSMB9HLA-Frpt-1UBE2BF40G9.1ATPaseC44B7.1pas-1rpt-3HIST1H2ABrpt-6uba-1rpn-7PSMB8rpn-6pas-5NEDD4rpn-12PSMD1Peptidaseproteasepas-2rpn-1PSMB7M01A10.3PSME2HLA-Bpbs-1rpn-10PSMB10pas-4HLA-HHLA-G


Description

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
118348view13:30, 27 May 2021ZiskaConnected lines
117065view14:24, 16 May 2021EweitzModified title
78051view12:24, 23 November 2014EgonwRemoved database source when no identifier was given.
68456view20:15, 5 July 2013MaintBotUpdated to 2013 gpml schema
67614view11:33, 26 June 2013DdiglesOntology Term : 'ubiquitin/proteasome degradation pathway' added !
40611view19:56, 1 March 2011MaintBotRemoved redundant pathway information and comments
21668view11:32, 14 November 2008MaintBot[[Pathway:Caenorhabditis elegans:Proteasome Degradation]] moved to [[Pathway:WP470]]: Moved to stable identifier
9023view14:14, 7 January 2008MaintBotAdded to category $category
9021view14:14, 7 January 2008NsalomonisUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATPaseGeneProduct172238 (Entrez Gene)
ATPaseGeneProduct178988 (Entrez Gene)
C44B7.1GeneProduct174129 (Entrez Gene)
F40G9.1GeneProduct175187 (Entrez Gene)
HIST1H2ABGeneProduct (Entrez Gene)
HLA-AGeneProduct (Entrez Gene)
HLA-BGeneProduct (Entrez Gene)
HLA-CGeneProduct (Entrez Gene)
HLA-EGeneProduct (Entrez Gene)
HLA-FGeneProduct (Entrez Gene)
HLA-GGeneProduct (Entrez Gene)
HLA-HGeneProduct (Entrez Gene)
HLA-JGeneProduct (Entrez Gene)
IFNGGeneProduct (Entrez Gene)
M01A10.3GeneProduct172208 (Entrez Gene)
NEDD4GeneProduct (Entrez Gene)
PSMB10GeneProduct (Entrez Gene)
PSMB4GeneProduct (Entrez Gene)
PSMB7GeneProduct (Entrez Gene)
PSMB8GeneProduct (Entrez Gene)
PSMB9GeneProduct (Entrez Gene)
PSMD1GeneProduct (Entrez Gene)
PSMD5GeneProduct (Entrez Gene)
PSME1GeneProduct (Entrez Gene)
PSME2GeneProduct (Entrez Gene)
PeptidaseGeneProduct173858 (Entrez Gene)
R08C7.3GeneProduct177212 (Entrez Gene)
UBE1LGeneProduct (Entrez Gene)
UBE2BGeneProduct (Entrez Gene)
UBE2D1GeneProduct (Entrez Gene)
UBE2D2GeneProduct (Entrez Gene)
Y66D12A.9GeneProduct176588 (Entrez Gene)
endopeptidaseGeneProduct172139 (Entrez Gene)
glycotransferaseGeneProduct177456 (Entrez Gene)
his-35GeneProduct179339 (Entrez Gene)
let-70GeneProduct178006 (Entrez Gene)
pas-1GeneProduct179941 (Entrez Gene)
pas-2GeneProduct179493 (Entrez Gene)
pas-4GeneProduct172679 (Entrez Gene)
pas-5GeneProduct172942 (Entrez Gene)
pas-7GeneProduct174571 (Entrez Gene)
pbs-1GeneProduct176978 (Entrez Gene) U13393
pbs-5GeneProduct173334 (Entrez Gene)
pbs-6GeneProduct176161 (Entrez Gene)
peptidaseGeneProduct171975 (Entrez Gene)
proteaseGeneProduct178943 (Entrez Gene)
rpn-10GeneProduct172977 (Entrez Gene)
rpn-1GeneProduct177455 (Entrez Gene)
rpn-12GeneProduct174786 (Entrez Gene)
rpn-3GeneProduct176196 (Entrez Gene)
rpn-5GeneProduct173807 (Entrez Gene)
rpn-6GeneProduct175972 (Entrez Gene)
rpn-7GeneProduct177753 (Entrez Gene)
rpn-8GeneProduct172009 (Entrez Gene)
rpn-9GeneProduct174715 (Entrez Gene)
rpt-1GeneProduct179641 (Entrez Gene)
rpt-3GeneProduct175925 (Entrez Gene) PRS6_HUMAN
rpt-4GeneProduct173384 (Entrez Gene)
rpt-6GeneProduct176661 (Entrez Gene) PRS6_HUMAN
uba-1GeneProduct177855 (Entrez Gene)
ubq-1GeneProduct175840 (Entrez Gene)

Annotated Interactions

No annotated interactions

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