GPCRs, class A rhodopsin-like (Rattus norvegicus)

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GP40 likeAPJ likeNeuropeptide YClass A OrphansThyrotropin-releasing hormone and SecretagogueMas proto-oncogeneAmineAcetylcholine (muscarinic)Hormone proteinFollicle stimulating hormonePurinoceptor type YOther Chemokine ReceptorsGPR45 likeOpioidMelatoninBombesinVasopressin-likeOrexin & neuropeptide FFCannabisBeta AdrenoceptorsSomatostatinChemokineC-C ChemokineCCKPlatelet activating factorBONZO receptors (CXC6R)C-X-C ChemokineNucleotide-likeAdenosine(Rhod)opsinRhodopsin VertebrateClass A Orphan/otherPlatelet ADP & KI01 receptorsOlfactoryAdrenomedullin (G10D)ORPHLGR like (hormone receptors)MelanocortinAdrenoceptorsAlpha AdrenoceptorsInterleukin-8Fmet-leu-pheRhodopsin OtherChemokine receptor-likeC5a anaphylatoxinNeuromedin UThrombinPurinoceptorsEndothelinSREBLutropin-choriogonadotropic hormoneNeuropeptide Y / peptide YYOlfactory OtherSerotoninHtr1fF2rl2OR2D2GPR8OR2N1PGpr31Lpar5Opn4Npy5rGPR39Bdkrb2Ccr1Olr1662OPN1MWPtger2Adra2bGpr45OR1G1CckarOlr1075Fpr1HTR1ECysltr2Ffar2Gpr22Olr1512GPR42OxtrAdrb1GperP2ry4Bdkrb1Olr217Gpr37l1Olr1073RrhCxcr4Htr4Gpr37GhsrMC1RGpr87Mc2rSucnr1OR1A1Olr231OR7C1Cmklr1Hcrtr1Cxcr5Cxcr3Gpr3GPR109BNmur2Htr1bOlr1467OR3A4Olr1086Adra2cGPR6Ccbp2Olr1087OR12D3Hcrtr2P2ry14Ccr8Ffar3RhoOprl1Gpr19OR1A2Hrh1OR1F1CCR2Olr226Cxcr7Gpcr12Mtnr1aCcr5ADRA2AOR2B6Sstr2Agtr2Opn1swGpr4Htr6TrhrDrd5OR2J2Agtr1aNpbwr1Gpr35Lpar4RgrGalr2EdnraHtr2aHtr1dGpr34Galr3OR1C1Cx3cr1Olr836OR2A4LOC685243Ccr7GPR77Opn3OR1D5Olr227PtgfrGpr1FshrPtger4Adra1bOlr1749AplnrSstr3Chrm5PtgirSstr1Gpr27OR1D2Adra1dHrh2Chrm3Opn1mwPTGDROlr1579Gpr52Olr1329Gpr171Gpr25Ccrl2Gpr44Adrb3RGD1563245HistamineGpr83GrprAdora2bMAS1LNpffr2Gpr173P2ry5Gpr85Gpr68P2ry2Ccr6Olr1077CckbrOR2B3Q9UDD9NmbrF2rl1GPR17Ffar1Ccr10Adora2aGPR32Npy2rBrs3Cnr1BradykininMLNRHtr7Avpr2Drd2Fpr2Tbxa2rGpr18Ntsr1Angiotensin IIOlr808Gpr81Cnr2ProstaglandinNpffr1Cysltr1Olr1356Oprm1Gpr50NPY6ROlr811P2ry6Fpr3Hrh3Mc5rIl8raDrd4Ccr4P2ry13Ppyr1Oprd1PtafrMtnr1bOlr1750OR1D4Mas1P2ry1Ptger1Gpr15Adora3OR10H1OR3A3Avpr1aF2rNTSR2Ccr9Htr1aSstr5Htr2bAdora1Olr1693F2RL3Olr464Gpr20Olr1743Chrm4Il8rbAvpr1bGpr21Olr420Olr806C3ar1EdnrbSstr4OR10H3Htr2cMc3rOR10H2NPY1RGALR1Adrb2Olr1654Olr1606OR2J1P2ry10Drd1aGpr65Olr1201Chrm2Gpr174Nmur1Xcr1Gpr75Mchr1Drd3Olr588Ptger3Ltb4rOlr1517Ccr3P2ry12Chrm1DopamineGpr63Olr1466Olr1730Htr5aLhcgrAdra1aP2RY11Mc4rOprk1PrlhrOlr1671


Description

No description

Comments

GenMAPP notes 
This MAPP was created using the GPCRDB (Horn et al., 1998), http://www.cmbi.kun.nl/7tm/. The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP455(r21638) with a 80% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
125508view01:28, 24 February 2023AlexanderPicofix description
116970view10:28, 16 May 2021EweitzModified title
106994view13:45, 17 September 2019MaintBotHMDB identifier normalization
93182view12:54, 2 August 2017DeSlChanged incorrect ChEBI ID for bradykinin to correct one.
72158view12:06, 25 October 2013EgonwAdded metabolite IDs.
71776view20:31, 17 October 2013MaintBotAutomated update of data sources
71296view16:57, 17 October 2013MaintBotAutomated update of data sources
69352view18:53, 8 July 2013MaintBotUpdated to 2013 gpml schema
67318view10:36, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway' added !
62845view05:03, 3 May 2013MaintBotUpdated UniProt data source
41664view02:35, 2 March 2011MaintBotRemoved redundant pathway information and comments
34059view19:05, 9 December 2009MaintBotAutomatic update of empty xrefs
32441view17:18, 15 August 2009MaintBotFixed text labels
32114view13:49, 14 August 2009MaintBotFixed group labels
31459view21:14, 13 August 2009MaintBotFixed text labels
31013view01:05, 30 July 2009MaintBotConverted from Homo sapiens
21674view11:32, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:GPCRDB Class A Rhodopsin-like]] moved to [[Pathway:WP473]]: Moved to stable identifier
8106view13:46, 7 January 2008MaintBot[[Pathway:Rat:GPCRDB Class A Rhodopsin-like]] moved to [[Pathway:Rattus norvegicus:GPCRDB Class A Rhodopsin-like]]: Renaming species
7674view16:08, 18 December 2007MaintBotfixed category names
7418view12:42, 4 November 2007MaintBotAdded categories to GPML
6545view22:20, 22 May 2007169.230.77.174gpml file for [[Rat:GPCRDB_Class_A_Rhodopsin-like]]

External references

DataNodes

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NameTypeDatabase referenceComment
ADRA2AGeneProduct25083 (Entrez Gene)
Adora1GeneProduct29290 (Entrez Gene)
Adora2aGeneProduct25369 (Entrez Gene)
Adora2bGeneProduct29316 (Entrez Gene)
Adora3GeneProduct25370 (Entrez Gene)
Adra1aGeneProduct29412 (Entrez Gene)
Adra1bGeneProduct24173 (Entrez Gene)
Adra1dGeneProduct29413 (Entrez Gene)
Adra2bGeneProduct24174 (Entrez Gene)
Adra2cGeneProduct24175 (Entrez Gene)
Adrb1GeneProduct24925 (Entrez Gene)
Adrb2GeneProduct24176 (Entrez Gene)
Adrb3GeneProduct25645 (Entrez Gene)
Agtr1aGeneProduct24180 (Entrez Gene)
Agtr2GeneProduct24182 (Entrez Gene)
Angiotensin IIMetaboliteHMDB01035 (HMDB)
AplnrGeneProduct83518 (Entrez Gene)
Avpr1aGeneProduct25107 (Entrez Gene)
Avpr1bGeneProduct29462 (Entrez Gene)
Avpr2GeneProduct25108 (Entrez Gene)
Bdkrb1GeneProduct81509 (Entrez Gene)
Bdkrb2GeneProduct25245 (Entrez Gene)
BradykininMetaboliteCHEBI:225208 (ChEBI)
Brs3GeneProduct260319 (Entrez Gene)
C3ar1GeneProduct84007 (Entrez Gene)
CCR2GeneProduct60463 (Entrez Gene)
Ccbp2GeneProduct140473 (Entrez Gene)
CckarGeneProduct24889 (Entrez Gene)
CckbrGeneProduct25706 (Entrez Gene)
Ccr10GeneProduct363682 (Entrez Gene)
Ccr1GeneProduct57301 (Entrez Gene)
Ccr3GeneProduct117027 (Entrez Gene)
Ccr4GeneProduct171054 (Entrez Gene)
Ccr5GeneProduct117029 (Entrez Gene)
Ccr6GeneProduct308163 (Entrez Gene)
Ccr7GeneProduct287673 (Entrez Gene)
Ccr8GeneProduct301066 (Entrez Gene)
Ccr9GeneProduct282832 (Entrez Gene)
Ccrl2GeneProduct316019 (Entrez Gene)
Chrm1GeneProduct25229 (Entrez Gene)
Chrm2GeneProduct81645 (Entrez Gene)
Chrm3GeneProduct24260 (Entrez Gene)
Chrm4GeneProduct25111 (Entrez Gene)
Chrm5GeneProduct53949 (Entrez Gene)
Cmklr1GeneProduct60669 (Entrez Gene)
Cnr1GeneProduct25248 (Entrez Gene)
Cnr2GeneProduct57302 (Entrez Gene)
Cx3cr1GeneProduct171056 (Entrez Gene)
Cxcr3GeneProduct84475 (Entrez Gene)
Cxcr4GeneProduct60628 (Entrez Gene)
Cxcr5GeneProduct29363 (Entrez Gene)
Cxcr7GeneProduct84348 (Entrez Gene)
Cysltr1GeneProduct114099 (Entrez Gene)
Cysltr2GeneProduct170926 (Entrez Gene)
DopamineMetaboliteCHEBI:18243 (ChEBI)
Drd1aGeneProduct24316 (Entrez Gene)
Drd2GeneProduct24318 (Entrez Gene)
Drd3GeneProduct29238 (Entrez Gene)
Drd4GeneProduct25432 (Entrez Gene)
Drd5GeneProduct25195 (Entrez Gene)
EdnraGeneProduct24326 (Entrez Gene)
EdnrbGeneProduct50672 (Entrez Gene)
F2RL3GeneProduct116498 (Entrez Gene)
F2rGeneProduct25439 (Entrez Gene)
F2rl1GeneProduct116677 (Entrez Gene)
F2rl2GeneProduct29636 (Entrez Gene)
Ffar1GeneProduct266607 (Entrez Gene)
Ffar2GeneProduct292794 (Entrez Gene)
Ffar3GeneProduct365228 (Entrez Gene)
Fpr1GeneProduct292409 (Entrez Gene)
Fpr2GeneProduct690158 (Entrez Gene)
Fpr3GeneProduct292413 (Entrez Gene)
FshrGeneProduct25449 (Entrez Gene)
GALR1GeneProduct50577 (Entrez Gene)
GPR109BGeneProduct
GPR17GeneProduct767613 (Entrez Gene)
GPR32GeneProduct
GPR39GeneProduct288995 (Entrez Gene)
GPR42GeneProduct
GPR6GeneProduct83683 (Entrez Gene)
GPR77GeneProduct445269 (Entrez Gene)
GPR8GeneProduct
Galr2GeneProduct29234 (Entrez Gene)
Galr3GeneProduct29235 (Entrez Gene)
GhsrGeneProduct84022 (Entrez Gene)
Gpcr12GeneProduct80840 (Entrez Gene)
GperGeneProduct171104 (Entrez Gene)
Gpr1GeneProduct25457 (Entrez Gene)
Gpr15GeneProduct288181 (Entrez Gene)
Gpr171GeneProduct688737 (Entrez Gene)
Gpr173GeneProduct64021 (Entrez Gene)
Gpr174GeneProduct302373 (Entrez Gene)
Gpr18GeneProduct679957 (Entrez Gene)
Gpr19GeneProduct312787 (Entrez Gene)
Gpr20GeneProduct60667 (Entrez Gene)
Gpr21GeneProduct689917 (Entrez Gene)
Gpr22GeneProduct298944 (Entrez Gene)
Gpr25GeneProduct363993 (Entrez Gene)
Gpr27GeneProduct65275 (Entrez Gene)
Gpr31GeneProduct292310 (Entrez Gene)
Gpr3GeneProduct266769 (Entrez Gene)
Gpr34GeneProduct554353 (Entrez Gene)
Gpr35GeneProduct367315 (Entrez Gene)
Gpr37GeneProduct117549 (Entrez Gene)
Gpr37l1GeneProduct252939 (Entrez Gene)
Gpr4GeneProduct308408 (Entrez Gene)
Gpr44GeneProduct309212 (Entrez Gene)
Gpr45GeneProduct301372 (Entrez Gene)
Gpr50GeneProduct117097 (Entrez Gene)
Gpr52GeneProduct680192 (Entrez Gene)
Gpr63GeneProduct297952 (Entrez Gene)
Gpr65GeneProduct299242 (Entrez Gene)
Gpr68GeneProduct314386 (Entrez Gene)
Gpr75GeneProduct498434 (Entrez Gene)
Gpr81GeneProduct689936 (Entrez Gene)
Gpr83GeneProduct140595 (Entrez Gene)
Gpr85GeneProduct64020 (Entrez Gene)
Gpr87GeneProduct310443 (Entrez Gene)
GrprGeneProduct24938 (Entrez Gene)
HTR1EGeneProduct
Hcrtr1GeneProduct25593 (Entrez Gene)
Hcrtr2GeneProduct25605 (Entrez Gene)
HistamineMetaboliteCHEBI:18295 (ChEBI)
Hrh1GeneProduct24448 (Entrez Gene)
Hrh2GeneProduct25461 (Entrez Gene)
Hrh3GeneProduct85268 (Entrez Gene)
Htr1aGeneProduct24473 (Entrez Gene)
Htr1bGeneProduct25075 (Entrez Gene)
Htr1dGeneProduct25323 (Entrez Gene)
Htr1fGeneProduct60448 (Entrez Gene)
Htr2aGeneProduct29595 (Entrez Gene)
Htr2bGeneProduct29581 (Entrez Gene)
Htr2cGeneProduct25187 (Entrez Gene)
Htr4GeneProduct25324 (Entrez Gene)
Htr5aGeneProduct25689 (Entrez Gene)
Htr6GeneProduct64354 (Entrez Gene)
Htr7GeneProduct65032 (Entrez Gene)
Il8raGeneProduct54258 (Entrez Gene)
Il8rbGeneProduct29385 (Entrez Gene)
LOC685243GeneProduct685243 (Entrez Gene)
LhcgrGeneProduct25477 (Entrez Gene)
Lpar4GeneProduct302378 (Entrez Gene)
Lpar5GeneProduct500317 (Entrez Gene)
Ltb4rGeneProduct59264 (Entrez Gene)
MAS1LGeneProduct
MC1RGeneProduct292083 (Entrez Gene)
MLNRGeneProduct
Mas1GeneProduct25153 (Entrez Gene)
Mc2rGeneProduct282839 (Entrez Gene)
Mc3rGeneProduct29310 (Entrez Gene)
Mc4rGeneProduct25635 (Entrez Gene)
Mc5rGeneProduct25726 (Entrez Gene)
Mchr1GeneProduct83567 (Entrez Gene)
Mtnr1aGeneProduct114211 (Entrez Gene)
Mtnr1bGeneProduct192646 (Entrez Gene)
NPY1RGeneProduct29358 (Entrez Gene)
NPY6RGeneProduct
NTSR2GeneProduct64636 (Entrez Gene)
NmbrGeneProduct25264 (Entrez Gene)
Nmur1GeneProduct65276 (Entrez Gene)
Nmur2GeneProduct64042 (Entrez Gene)
Npbwr1GeneProduct297795 (Entrez Gene)
Npffr1GeneProduct64107 (Entrez Gene)
Npffr2GeneProduct78964 (Entrez Gene)
Npy2rGeneProduct66024 (Entrez Gene)
Npy5rGeneProduct25340 (Entrez Gene)
Ntsr1GeneProduct366274 (Entrez Gene)
OPN1MWGeneProduct89810 (Entrez Gene)
OR10H1GeneProduct
OR10H2GeneProduct
OR10H3GeneProduct
OR12D3GeneProduct
OR1A1GeneProduct
OR1A2GeneProduct
OR1C1GeneProduct
OR1D2GeneProduct
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OR1F1GeneProduct
OR1G1GeneProduct
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OR2B3GeneProduct
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OR2D2GeneProduct
OR2J1GeneProduct
OR2J2GeneProduct
OR2N1PGeneProduct
OR3A3GeneProduct
OR3A4GeneProduct
OR7C1GeneProduct
Olr1073GeneProduct405362 (Entrez Gene)
Olr1075GeneProduct299596 (Entrez Gene)
Olr1077GeneProduct405280 (Entrez Gene)
Olr1086GeneProduct299588 (Entrez Gene)
Olr1087GeneProduct299586 (Entrez Gene)
Olr1201GeneProduct405106 (Entrez Gene)
Olr1329GeneProduct405075 (Entrez Gene)
Olr1356GeneProduct302954 (Entrez Gene)
Olr1466GeneProduct287480 (Entrez Gene)
Olr1467GeneProduct287481 (Entrez Gene)
Olr1512GeneProduct287511 (Entrez Gene)
Olr1517GeneProduct287516 (Entrez Gene)
Olr1579GeneProduct289239 (Entrez Gene)
Olr1606GeneProduct305711 (Entrez Gene)
Olr1654GeneProduct60451 (Entrez Gene)
Olr1662GeneProduct291361 (Entrez Gene)
Olr1671GeneProduct294138 (Entrez Gene)
Olr1693GeneProduct365523 (Entrez Gene)
Olr1730GeneProduct294187 (Entrez Gene)
Olr1743GeneProduct294197 (Entrez Gene)
Olr1749GeneProduct294203 (Entrez Gene)
Olr1750GeneProduct294204 (Entrez Gene)
Olr217GeneProduct293364 (Entrez Gene)
Olr226GeneProduct65140 (Entrez Gene)
Olr227GeneProduct293370 (Entrez Gene)
Olr231GeneProduct293375 (Entrez Gene)
Olr420GeneProduct296682 (Entrez Gene)
Olr464GeneProduct295734 (Entrez Gene)
Olr588GeneProduct295822 (Entrez Gene)
Olr806GeneProduct405331 (Entrez Gene)
Olr808GeneProduct405140 (Entrez Gene)
Olr811GeneProduct405138 (Entrez Gene)
Olr836GeneProduct298394 (Entrez Gene)
Opn1mwGeneProduct89810 (Entrez Gene)
Opn1swGeneProduct81644 (Entrez Gene)
Opn3GeneProduct498289 (Entrez Gene)
Opn4GeneProduct192223 (Entrez Gene)
Oprd1GeneProduct24613 (Entrez Gene)
Oprk1GeneProduct29335 (Entrez Gene)
Oprl1GeneProduct29256 (Entrez Gene)
Oprm1GeneProduct25601 (Entrez Gene)
OxtrGeneProduct25342 (Entrez Gene)
P2RY11GeneProduct
P2ry10GeneProduct317219 (Entrez Gene)
P2ry1GeneProduct25265 (Entrez Gene)
P2ry12GeneProduct64803 (Entrez Gene)
P2ry13GeneProduct310444 (Entrez Gene)
P2ry14GeneProduct171108 (Entrez Gene)
P2ry2GeneProduct29597 (Entrez Gene)
P2ry4GeneProduct63843 (Entrez Gene)
P2ry5GeneProduct691774 (Entrez Gene)
P2ry6GeneProduct117264 (Entrez Gene)
PTGDRGeneProduct498475 (Entrez Gene)
Ppyr1GeneProduct29471 (Entrez Gene)
PrlhrGeneProduct246075 (Entrez Gene)
ProstaglandinMetaboliteCHEBI:26333 (ChEBI)
PtafrGeneProduct58949 (Entrez Gene)
Ptger1GeneProduct25637 (Entrez Gene)
Ptger2GeneProduct81752 (Entrez Gene)
Ptger3GeneProduct24929 (Entrez Gene)
Ptger4GeneProduct84023 (Entrez Gene)
PtgfrGeneProduct25652 (Entrez Gene)
PtgirGeneProduct292661 (Entrez Gene)
Q9UDD9GeneProduct
RGD1563245GeneProduct289180 (Entrez Gene)
RgrGeneProduct306307 (Entrez Gene)
RhoGeneProduct24717 (Entrez Gene)
RrhGeneProduct310869 (Entrez Gene)
SerotoninMetaboliteCHEBI:28790 (ChEBI)
Sstr1GeneProduct25033 (Entrez Gene)
Sstr2GeneProduct54305 (Entrez Gene)
Sstr3GeneProduct171044 (Entrez Gene)
Sstr4GeneProduct25555 (Entrez Gene)
Sstr5GeneProduct25354 (Entrez Gene)
Sucnr1GeneProduct408199 (Entrez Gene)
Tbxa2rGeneProduct24816 (Entrez Gene)
TrhrGeneProduct25570 (Entrez Gene)
Xcr1GeneProduct301086 (Entrez Gene)

Annotated Interactions

No annotated interactions
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