Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

Ras signaling (Homo sapiens)

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Ras signaling
Evading growth suppressors

Cell cycle (Homo sapiens)

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Cell cycle
Activating invasion and metastasis

Epithelial to mesenchymal transition in colorectal cancer (Homo sapiens)

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Epithelial to mesenchymal transition in colorectal cancer
Enabling replicative immortality

Regulation of Wnt / B-catenin signaling by small molecule compounds (Homo sapiens)

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Regulation of Wnt / B-catenin signaling by small molecule compounds
Inducing angiogenesis

VEGFA-VEGFR2 signaling (Homo sapiens)

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VEGFA-VEGFR2 signaling
Resisting cell death

Target of rapamycin signaling (Homo sapiens)

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Target of rapamycin signaling
Deregulating cellular energetics

Hereditary leiomyomatosis and renal cell carcinoma pathway (Homo sapiens)

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Hereditary leiomyomatosis and renal cell carcinoma pathway
Genome instability and mutation

DNA IR-damage and cellular response via ATR (Homo sapiens)

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DNA IR-damage and cellular response via ATR
Tumor promoting inflammation

Chemokine signaling (Homo sapiens)

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Chemokine signaling
Avoiding immune destruction

Altered glycosylation of MUC1 in tumor microenvironment (Homo sapiens)

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Altered glycosylation of MUC1 in tumor microenvironment
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