Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

ErbB signaling (Homo sapiens)

ErbB signaling
ErbB signaling
Evading growth suppressors

Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer (Homo sapiens)

Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer
Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer
Activating invasion and metastasis

Integrin-mediated cell adhesion (Homo sapiens)

Integrin-mediated cell adhesion
Integrin-mediated cell adhesion
Enabling replicative immortality

Regulation of Wnt / B-catenin signaling by small molecule compounds (Homo sapiens)

Regulation of Wnt / B-catenin signaling by small molecule compounds
Regulation of Wnt / B-catenin signaling by small molecule compounds
Inducing angiogenesis

PDGF pathway (Homo sapiens)

PDGF pathway
PDGF pathway
Resisting cell death

PI3K-AKT-mTOR signaling and therapeutic opportunities in prostate cancer (Homo sapiens)

PI3K-AKT-mTOR signaling and therapeutic opportunities in prostate cancer
PI3K-AKT-mTOR signaling and therapeutic opportunities in prostate cancer
Deregulating cellular energetics

Metabolic reprogramming in colon cancer (Homo sapiens)

Metabolic reprogramming in colon cancer
Metabolic reprogramming in colon cancer
Genome instability and mutation

DNA IR-double strand breaks and cellular response via ATM (Homo sapiens)

DNA IR-double strand breaks and cellular response via ATM
DNA IR-double strand breaks and cellular response via ATM
Tumor promoting inflammation

Cytokines and inflammatory response (Homo sapiens)

Cytokines and inflammatory response
Cytokines and inflammatory response
Avoiding immune destruction

Altered glycosylation of MUC1 in tumor microenvironment (Homo sapiens)

Altered glycosylation of MUC1 in tumor microenvironment
Altered glycosylation of MUC1 in tumor microenvironment
Therapeutics

Imatinib and chronic myeloid leukemia (Homo sapiens)

Imatinib and chronic myeloid leukemia
Imatinib and chronic myeloid leukemia
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