Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

Ras signaling (Homo sapiens)

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Ras signaling
Evading growth suppressors

TGF-beta receptor signaling (Homo sapiens)

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TGF-beta receptor signaling
Activating invasion and metastasis

Focal adhesion: PI3K-Akt-mTOR-signaling (Homo sapiens)

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Focal adhesion: PI3K-Akt-mTOR-signaling
Enabling replicative immortality

Wnt signaling (Homo sapiens)

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Wnt signaling
Inducing angiogenesis

Angiogenesis (Homo sapiens)

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Angiogenesis
Resisting cell death

Apoptosis (Homo sapiens)

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Apoptosis
Deregulating cellular energetics

Metabolic reprogramming in colon cancer (Homo sapiens)

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Metabolic reprogramming in colon cancer
Genome instability and mutation

Nucleotide excision repair (Homo sapiens)

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Nucleotide excision repair
Tumor promoting inflammation

Cytokines and inflammatory response (Homo sapiens)

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Cytokines and inflammatory response
Avoiding immune destruction

Altered glycosylation of MUC1 in tumor microenvironment (Homo sapiens)

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Altered glycosylation of MUC1 in tumor microenvironment
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