Portal:CPTAC/Hallmarks

Sustaining proliferative signaling Ras signaling (Homo sapiens) Ras signaling	Evading growth suppressors Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer (Homo sapiens) Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer	Activating invasion and metastasis H19, Rb-E2F1, and CDK-beta-catenin in colorectal cancer (Homo sapiens) H19, Rb-E2F1, and CDK-beta-catenin in colorectal cancer
Enabling replicative immortality Wnt signaling (Homo sapiens) Wnt signaling	Inducing angiogenesis PDGF pathway (Homo sapiens) PDGF pathway	Resisting cell death Target of rapamycin signaling (Homo sapiens) Target of rapamycin signaling
Deregulating cellular energetics Glycolysis and gluconeogenesis (Homo sapiens) Glycolysis and gluconeogenesis	Genome instability and mutation Direct reversal repair (Homo sapiens) Direct reversal repair	Tumor promoting inflammation Cytokines and inflammatory response (Homo sapiens) Cytokines and inflammatory response
Avoiding immune destruction Type II interferon signaling (Homo sapiens) Type II interferon signaling	Therapeutics MicroRNA for targeting cancer growth and vascularization in glioblastoma (Homo sapiens) MicroRNA for targeting cancer growth and vascularization in glioblastoma