Serotonin HTR1 group and FOS pathway (Homo sapiens)

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39, 76, 128, 146, 148...1792079318, 32, 52, 59, 92...20733, 49, 84, 132, 229...2928, 42, 99, 144, 165...14, 195, 30619, 21, 27, 43, 114...90, 111, 251, 265, 269...41, 157, 276, 337262, 270, 272, 329, 3661, 31, 37, 125, 204...26, 88, 115, 130, 140...7, 44, 91, 102, 120...145, 175, 183, 238, 3301621624, 124, 18182, 89, 29651, 105, 126, 131, 161...97, 152, 212, 299, 301...2219647, 56, 62, 288, 31016222815, 63, 72, 85, 29516, 17, 38, 95, 154...7, 45, 91, 113, 209...100, 16227940, 65, 116, 118, 138...16254, 71, 74, 94, 169...139, 15125, 77, 109, 143, 182...36955, 29324730, 79, 168, 220, 221, 230...20735, 137, 193, 261, 286...2, 3, 34, 83, 86...20, 98, 174, 33936, 69, 110, 172, 206...64, 7548, 171, 189, 208, 3124624716216212, 121, 164, 197, 35620721057, 61, 200, 23419267, 119, 158, 186-188, 232...10, 24, 68, 81, 155...9316214178, 103, 104, 191, 22658, 60, 338102, 134, 153, 223332416280, 112, 122, 170, 176...224, 231, 263, 30050, 108, 127, 129, 173...13, 53, 219, 233, 258...28, 135, 205, 274, 28440, 87, 107, 133, 142...73, 2909, 29, 66, 70, 147...ReceptorBindingSmall MoleculeLEGENDDirect RegulationPromoter BindingSynthesis Functional Protein ClassProteinIndirect RegulationProtein ModificationPKCELK1RASGRF1MAP3K1CREB1RPS6K1,4,5-Insp3HTR1FMAPK14PLCMAP2K2PDPK1FOSMAP2K6SRFMAP2K3RAP1ARPS6KA5SerotoninELK4PtdIns3PMAPKAPK31,2-DiacetinGNAI2HTR1BHTR1DHTR1AHTR1EGNAI3BRAFMAPKAPK2RHOAGNAO1ITPR1RASGRP1PI3KGNAI1MAP2K1MAPK1RasGb/gMAPK3CALCIUM


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History

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CompareRevisionActionTimeUserComment
125764view14:31, 9 March 2023DeSlAdded rhea ID and ref. for PI3K interaction
125763view14:27, 9 March 2023DeSlFixed PI3K enzyme conversion
125656view15:59, 6 March 2023DeSlIntegrated description from WP733
125655view15:58, 6 March 2023DeSlIntegrated WP733
125651view15:51, 6 March 2023DeSlAdded two annotations
125650view15:47, 6 March 2023DeSlConverted (in)direct regulation to MIM-stimulation
125649view15:43, 6 March 2023DeSlVretical layout, converted arrow to MIM-conversion
125648view15:41, 6 March 2023DeSlChanged layout
125647view15:40, 6 March 2023DeSlConverted some arrows to specific MIM-types
125646view15:35, 6 March 2023DeSlUpdating to current color scheme
125633view02:01, 6 March 2023AlexanderPicoModified description
125272view15:34, 31 January 2023EgonwFixed two more references
125271view15:22, 31 January 2023EgonwFixed a reference
120570view01:00, 17 December 2021Khanspersupdated lit refs
120569view00:58, 17 December 2021Khanspersupdated lit refs
120568view00:45, 17 December 2021Khanspersfixed literature references to remove weird characters
117823view15:06, 22 May 2021EweitzModified title
106177view12:07, 16 August 2019MaintBotHMDB identifier normalization
102357view19:43, 20 December 2018Fehrhartfixed unconnected lines
102125view17:03, 1 December 2018EgonwRemoved whitespace in PubMed identifiers.
74511view05:59, 27 April 2014EgonwLast batch of PubMed ID fixes.
74501view17:12, 26 April 2014EgonwMore PubMed ID fixes.
74499view16:58, 26 April 2014EgonwFixed PubMed IDs.
73767view00:49, 22 February 2014MaintBotupdating schema
49735view09:04, 25 July 2012AndraRDF Tidy
49638view10:31, 23 July 2012AndraRDF Tidy
49633view09:57, 23 July 2012AndraRDF Tidy
49625view09:24, 23 July 2012AndraRDF Tidy
49624view09:22, 23 July 2012AndraRDF Tidy
49621view08:51, 23 July 2012AndraRDF Tidy
49580view07:14, 21 July 2012AndraRDF Tidy
49556view19:33, 20 July 2012AndraRDF tidy
49540view09:59, 20 July 2012AndraCorrected references
49539view09:48, 20 July 2012AndraCorrected a erroneous pubmed reference
49534view09:06, 20 July 2012AndraCorrected a pubmed error
46093view03:28, 15 December 2011AlexanderPicoconverted more hugo to hgnc
45025view18:43, 6 October 2011ThomasOntology Term : 'serotonin signaling pathway' added !
41105view23:22, 1 March 2011MaintBotRemoved redundant pathway information and comments
39767view07:54, 17 January 2011AlexanderPico
34469view18:32, 10 December 2009MaintBotAutomatic update of empty xrefs
33424view14:53, 30 November 2009MaintBotRemoved group label
33185view17:56, 5 November 2009KhanspersModified categories
31150view04:01, 5 August 2009ArukeModified description
30189view21:58, 8 July 2009ArukePeriodical save, work in progress
30183view04:17, 8 July 2009ArukePeriodical save, work in progress
30177view18:15, 7 July 2009ArukeAdded legend
30176view18:05, 7 July 2009ArukePeriodical save, work in progress
30071view18:39, 30 June 2009ArukeSpecify description
30070view18:37, 30 June 2009ArukePeriodical save, work in progress
30069view18:34, 30 June 2009ArukeSpecify description

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1,2-DiacetinMetabolite102-62-5 (CAS) diacylglycerol
1,4,5-Insp3Metabolite85166-31-0 (CAS)
BRAFGeneProduct673 (Entrez Gene) v-raf murine sarcoma viral oncogene homolog B1
CALCIUMMetabolite7440-70-2 (CAS)
CREB1GeneProduct1385 (Entrez Gene) cAMP response element-binding protein 1
ELK1GeneProduct2002 (Entrez Gene) ELK1, member of ETS oncogene family
ELK4GeneProduct2005 (Entrez Gene) ETS domain-containing protein Elk-4 (SRF accessory protein 1)
FOSGeneProduct2353 (Entrez Gene) proto-oncogene protein c-fos
GNAI1Protein2770 (Entrez Gene)
GNAI2Protein2771 (Entrez Gene)
GNAI3Protein2773 (Entrez Gene)
GNAO1Protein2775 (Entrez Gene)
Gb/gComplex
HTR1AProtein3350 (Entrez Gene)
HTR1BProtein3351 (Entrez Gene)
HTR1DProtein3352 (Entrez Gene)
HTR1EProtein3354 (Entrez Gene)
HTR1FProtein3355 (Entrez Gene)
ITPR1GeneProduct3708 (Entrez Gene) inositol 1,4,5-triphosphate receptor 1
MAP2K1GeneProduct5604 (Entrez Gene) mitogen activated protein kinase kinase 1
MAP2K2GeneProduct5605 (Entrez Gene) mitogen activated protein kinase kinase 2
MAP2K3GeneProduct5606 (Entrez Gene) mitogen activated protein kinase kinase 3
MAP2K6GeneProduct5608 (Entrez Gene) mitogen activated protein kinase kinase 6
MAP3K1GeneProduct4214 (Entrez Gene) mitogen activated protein kinase kinase kinase 1
MAPK14GeneProduct1432 (Entrez Gene) mitogen activated protein kinase 14
MAPK1GeneProductMAPK1 (HGNC) mitogen activated protein kinase 1
MAPK3GeneProduct5595 (Entrez Gene) mitogen activated protein kinase 3
MAPKAPK2GeneProduct9261 (Entrez Gene) mitogen activated protein kinase 3
MAPKAPK3GeneProduct7867 (Entrez Gene) mitogen-activated protein kinase-activated protein kinase 3
PDPK1GeneProduct5170 (Entrez Gene) 3-phosphoinositide dependent protein kinase-1
PI3KGeneProduct5290 (Entrez Gene) phosphatidylinositol 3-kinase
PKCGeneProduct50818 (Entrez Gene) protein kinase C
PLCGeneProductphospholipase C
PtdIns3PGeneProductphosphatidylinositol 3,4,5-triphosphate
RAP1AGeneProduct5906 (Entrez Gene) RAS-related protein-1a
RASGRF1GeneProduct5923 (Entrez Gene) RAS protein-specific guanine nucleotide-releasing factor 1
RASGRP1GeneProduct10125 (Entrez Gene) RAS guanyl releasing protein 1
RHOAGeneProduct387 (Entrez Gene) ras homolog gene family, member A
RPS6KGeneProductFunctional Class RPS6K (ribosomal protein S6 kinase)
RPS6KA5GeneProduct9252 (Entrez Gene) ribosomal protein S6 kinase, polypeptide 5
RasGeneProductRAS oncogene homolog
SRFGeneProduct6722 (Entrez Gene) serum response factor
SerotoninMetaboliteHMDB00259 (HMDB)

Annotated Interactions

No annotated interactions

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