Portal:CPTAC/Hallmark/Proliferative

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The normal control of cell growth and division in cells is governed by careful control and release of growth-promoting signals, but in cancer cells this control is deregulated.
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Signaling through growth factors via the tyrosine kinase domains of cell-surface receptors, trigger progression through the cell cycle and other pathways.
*[[Pathway:WP3972]] PDGFR-beta pathway
*[[Pathway:WP3972]] PDGFR-beta pathway
*[[Pathway:WP673]] ErbB Signaling Pathway
*[[Pathway:WP673]] ErbB Signaling Pathway

Revision as of 23:34, 3 December 2018

The normal control of cell growth and division in cells is governed by careful control and release of growth-promoting signals, but in cancer cells this control is deregulated. Signaling through growth factors via the tyrosine kinase domains of cell-surface receptors, trigger progression through the cell cycle and other pathways.