Portal:CPTAC/Hallmark/Proliferative
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The normal control of cell growth and division in cells is governed by careful control and release of growth-promoting signals, but in cancer cells this control is deregulated. | The normal control of cell growth and division in cells is governed by careful control and release of growth-promoting signals, but in cancer cells this control is deregulated. | ||
| - | Signaling through growth factors via the tyrosine kinase domains of cell-surface receptors, trigger progression through the cell cycle and other pathways. | + | Signaling through growth factors via the tyrosine kinase domains of cell-surface receptors, trigger progression through the cell cycle and other pathways. (Adapted from [https://www.ncbi.nlm.nih.gov/pubmed/21376230 Hallmarks of cancer: the next generation, Hanahan and Weinberg, Cell 2011]) |
*[[Pathway:WP3972]] PDGFR-beta pathway | *[[Pathway:WP3972]] PDGFR-beta pathway | ||
*[[Pathway:WP673]] ErbB Signaling Pathway | *[[Pathway:WP673]] ErbB Signaling Pathway | ||
Revision as of 23:42, 3 December 2018
The normal control of cell growth and division in cells is governed by careful control and release of growth-promoting signals, but in cancer cells this control is deregulated. Signaling through growth factors via the tyrosine kinase domains of cell-surface receptors, trigger progression through the cell cycle and other pathways. (Adapted from Hallmarks of cancer: the next generation, Hanahan and Weinberg, Cell 2011)
- Pathway:WP3972 PDGFR-beta pathway
- Pathway:WP673 ErbB Signaling Pathway
- Pathway:WP581 EPO Receptor Signaling
- Pathway:WP382 MAPK Signaling Pathway
- Pathway:WP4223 Ras Signaling
- Pathway:WP2828 Bladder Cancer
- Pathway:WP4205 MET in type 1 papillary renal cell carcinoma
- Pathway:WP4255 Non-small cell lung cancer
- Pathway:WP4263 Pancreatic adenocarcinoma pathway
- Pathway:WP4155 Endometrial cancer
