From WikiPathways
ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Bombesin Thyrotropin-releasing hormone and Secretagogue (Rhod)opsin Rhodopsin Vertebrate Interleukin-8 Lutropin-choriogonadotropic hormone Neuropeptide Y / peptide YY Melanocortin Class A Orphan/other Platelet ADP & KI01 receptors Adrenomedullin (G10D) Other Chemokine Receptors Adrenoceptors Alpha Adrenoceptors Olfactory APJ like Fmet-leu-phe Hormone protein Follicle stimulating hormone CCK Mas proto-oncogene ORPH LGR like (hormone receptors) Purinoceptor type Y Rhodopsin Other Orexin & neuropeptide FF Purinoceptors Opioid Somatostatin Melatonin C5a anaphylatoxin Nucleotide-like Adenosine Beta Adrenoceptors Cannabis Vasopressin-like GP40 like BONZO receptors (CXC6R) Chemokine receptor-like Chemokine C-C Chemokine Neuropeptide Y Amine Acetylcholine (muscarinic) Endothelin Platelet activating factor Class A Orphans Olfactory Other SREB Thrombin Neuromedin U C-X-C Chemokine GPR45 like Cx3cr1 P2ry2 Dopamine Bradykinin F2r Ptafr Prostaglandin Lhcgr Fshr Serotonin Aplnr Angiotensin II Histamine Fpr1 Fpr2 Fpr3 F2rl1 Galr2 F2RL3 GALR1 Oxtr Avpr1b F2rl2 Galr3 Avpr2 Avpr1a Drd2 Drd4 Drd3 Drd5 Drd1a Oprk1 Oprd1 Mtnr1b Mtnr1a Gpr50 Ptger1 Ptger4 Ptgfr Ptger2 Ptger3 Ptgir Tbxa2r PTGDR Ednra Ednrb GPR32 Cmklr1 Gpr44 Gper Cysltr2 Gpr45 Cysltr1 MC1R Mc2r Mc3r Mc4r Mc5r NPY6R NPY1R Npy5r Ppyr1 Npy2r Nmur2 Nmur1 GPR42 Ffar3 Ffar1 Ffar2 Hcrtr1 Hcrtr2 Npffr2 Npffr1 GPR77 C3ar1 Adora1 Adora2a Adora3 Adora2b P2ry13 P2ry14 Gpr87 P2ry12 Htr2b Htr1f Htr4 Htr1b Htr5a Htr6 HTR1E Htr1a Htr2a Htr7 Htr2c Htr1d Cckbr Cckar Il8rb Il8ra Olr1467 OR3A3 OR10H3 OR7C1 Olr1730 Olr1086 Olr1201 Olr1075 Olr836 OR2J2 OR1G1 Olr231 Olr1073 OR2B6 Olr1662 OR2B3 Olr1750 Olr464 OR1D2 OR1F1 OR1D5 Olr227 Olr226 OR1C1 Olr808 Olr1654 OR10H1 Olr1329 Olr1512 OR2A4 Olr1579 OR1A1 Olr1671 Olr588 OR2D2 Olr1077 OR10H2 OR2J1 OR2N1P Olr1517 OR1D4 OR1A2 Olr806 Olr420 Q9UDD9 Olr1743 Olr1466 Olr1356 Olr811 Olr1749 Olr1087 OR3A4 Adrb1 Adrb3 Adrb2 Cxcr5 Cxcr3 Cxcr4 Sstr5 Sstr4 Sstr2 Sstr1 Sstr3 MLNR Trhr Ghsr Bdkrb1 Bdkrb2 Gpr52 GPR17 GPR8 Gpr15 GPR6 Gpr19 Gpr22 Gpr31 Mchr1 Gpr1 Gpr63 Npbwr1 Prlhr Gpr3 Gpr21 Gpr4 Gpr20 Gpcr12 Gpr25 NTSR2 Ntsr1 Gpr83 Chrm2 Chrm4 Chrm3 Chrm1 Chrm5 Cnr1 Cnr2 P2ry10 P2ry4 P2ry6 Lpar5 P2ry1 Ltb4r Gpr35 Gpr174 P2RY11 Lpar4 P2ry5 Sucnr1 Gpr37l1 Gpr37 MAS1L GPR39 RGD1563245 Gpr34 Gpr68 Gpr65 GPR109B Gpr81 Gpr171 Gpr18 Gpr75 Hrh3 Hrh1 Hrh2 Rrh Rgr Opn4 Opn3 Gpr85 Gpr173 Gpr27 Xcr1 LOC685243 Ccr10 Ccr7 Ccr4 Ccr8 Ccr3 Ccrl2 Ccr6 Ccbp2 CCR2 Ccr1 Ccr5 Ccr9 Nmbr Grpr Brs3 Oprm1 Oprl1 OR12D3 Olr1693 Olr1606 Olr217 Agtr1a Agtr2 Cxcr7 Mas1 OPN1MW Rho Opn1sw Opn1mw ADRA2A Adra2c Adra1b Adra1a Adra1d Adra2b Name: GPCRs, class A rhodopsin-like Last Modified: 10/17/2013 Organism: Rattus norvegicus
Description
This pathway was created using the GPCRDB (Horn et al., 1998),
http://www.gpcr.org/7tm/ (originally at
http://www.cmbi.kun.nl/7tm/ ). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.
Comments
Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
Ontology Terms
Bibliography
No bibliography
History
External references
DataNodes
Annotated Interactions
No annotated interactions