Fluoroacetic acid toxicity (Homo sapiens)
From WikiPathways
Description
Pathway on fluoroacetic acid toxicity describing how it ultimately leads to disturbance of the Krebs cycle.
Quality Tags
Ontology Terms
Bibliography
- Johnson BM, Shu YZ, Zhuo X, Meanwell NA; ''Metabolic and Pharmaceutical Aspects of Fluorinated Compounds.''; J Med Chem, 2020 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
4-Hydroxy-trans-aconitate | Metabolite | Q76106265 (Wikidata) ![]() | |
ALDH2 | GeneProduct | ENSG00000111275 (Ensembl) ![]() | |
ALDH3A2 | GeneProduct | ENSG00000072210 (Ensembl) ![]() | |
ALDH9A1 | GeneProduct | ENSG00000143149 (Ensembl) ![]() | |
Acetate | Metabolite | 71-50-1 (CAS) ![]() | |
Acetyl-CoA synthetase | GeneProduct | ENSG00000131069 (Ensembl) ![]() | |
Aconitase | GeneProduct | ENSG00000100412 (Ensembl) ![]() | |
Citrate synthase | GeneProduct | 1431 (Entrez Gene) ![]() | |
Citric acid cycle (Krebs cycle) | Pathway | WP78 (WikiPathways) ![]() | |
Citric acid | Metabolite | CHEBI:30769 (ChEBI) ![]() | |
Fluoroacetaldehyde | Metabolite | CHEBI:14272 (ChEBI) ![]() | |
Fluoroacetic acid | Metabolite | CHEBI:30775 (ChEBI) ![]() | |
Fluoroacetyl-CoA | Metabolite | 49859653 (PubChem-compound) ![]() | |
Fluorocitric acid | Metabolite | 357-89-1 (CAS) ![]() | |
Isocitric acid | Metabolite | CHEBI:30887 (ChEBI) ![]() |
Annotated Interactions
No annotated interactions