Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

PDGFR-beta pathway (Homo sapiens)

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PDGFR-beta pathway
Evading growth suppressors

Cell cycle (Homo sapiens)

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Cell cycle
Activating invasion and metastasis

H19, Rb-E2F1, and CDK-beta-catenin in colorectal cancer (Homo sapiens)

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H19, Rb-E2F1, and CDK-beta-catenin in colorectal cancer
Enabling replicative immortality

Notch signaling (Homo sapiens)

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Notch signaling
Inducing angiogenesis

Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors (Homo sapiens)

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Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors
Resisting cell death

PI3K-AKT-mTOR signaling and therapeutic opportunities in prostate cancer (Homo sapiens)

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PI3K-AKT-mTOR signaling and therapeutic opportunities in prostate cancer
Deregulating cellular energetics

Hereditary leiomyomatosis and renal cell carcinoma pathway (Homo sapiens)

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Hereditary leiomyomatosis and renal cell carcinoma pathway
Genome instability and mutation

DNA damage response (Homo sapiens)

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DNA damage response
Tumor promoting inflammation

Cytokines and inflammatory response (Homo sapiens)

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Cytokines and inflammatory response
Avoiding immune destruction

Interferon type I signaling (Homo sapiens)

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Interferon type I signaling
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