Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma (Homo sapiens)

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FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma
Evading growth suppressors

G1 to S cell cycle control (Homo sapiens)

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G1 to S cell cycle control
Activating invasion and metastasis

Epithelial to mesenchymal transition in colorectal cancer (Homo sapiens)

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Epithelial to mesenchymal transition in colorectal cancer
Enabling replicative immortality

Notch signaling (Homo sapiens)

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Notch signaling
Inducing angiogenesis

VEGFA-VEGFR2 signaling (Homo sapiens)

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VEGFA-VEGFR2 signaling
Resisting cell death

TP53 network (Homo sapiens)

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TP53 network
Deregulating cellular energetics

Metabolic reprogramming in colon cancer (Homo sapiens)

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Metabolic reprogramming in colon cancer
Genome instability and mutation

Direct reversal repair (Homo sapiens)

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Direct reversal repair
Tumor promoting inflammation

IL6 signaling (Homo sapiens)

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IL6 signaling
Avoiding immune destruction

Type II interferon signaling (Homo sapiens)

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Type II interferon signaling
Therapeutics

Transcriptional activation by NRF2 in response to phytochemicals (Homo sapiens)

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Transcriptional activation by NRF2 in response to phytochemicals
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