Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

PDGFR-beta pathway (Homo sapiens)

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PDGFR-beta pathway
Evading growth suppressors

Cell cycle (Homo sapiens)

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Cell cycle
Activating invasion and metastasis

TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition (Homo sapiens)

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TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition
Enabling replicative immortality

Notch signaling (Homo sapiens)

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Notch signaling
Inducing angiogenesis

VEGFA-VEGFR2 signaling (Homo sapiens)

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VEGFA-VEGFR2 signaling
Resisting cell death

TP53 network (Homo sapiens)

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TP53 network
Deregulating cellular energetics

Glycolysis and gluconeogenesis (Homo sapiens)

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Glycolysis and gluconeogenesis
Genome instability and mutation

Direct reversal repair (Homo sapiens)

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Direct reversal repair
Tumor promoting inflammation

Cytokines and inflammatory response (Homo sapiens)

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Cytokines and inflammatory response
Avoiding immune destruction

Interferon type I signaling (Homo sapiens)

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Interferon type I signaling
Therapeutics

Fluoropyrimidine activity (Homo sapiens)

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Fluoropyrimidine activity
Personal tools