Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

MET in type 1 papillary renal cell carcinoma (Homo sapiens)

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MET in type 1 papillary renal cell carcinoma
Evading growth suppressors

Retinoblastoma gene in cancer (Homo sapiens)

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Retinoblastoma gene in cancer
Activating invasion and metastasis

MFAP5-mediated ovarian cancer cell motility and invasiveness (Homo sapiens)

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MFAP5-mediated ovarian cancer cell motility and invasiveness
Enabling replicative immortality

Wnt signaling (Homo sapiens)

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Wnt signaling
Inducing angiogenesis

Hedgehog signaling (Homo sapiens)

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Hedgehog signaling
Resisting cell death

miRNA regulation of p53 pathway in prostate cancer (Homo sapiens)

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miRNA regulation of p53 pathway in prostate cancer
Deregulating cellular energetics

Metabolic reprogramming in colon cancer (Homo sapiens)

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Metabolic reprogramming in colon cancer
Genome instability and mutation

DNA damage response (Homo sapiens)

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DNA damage response
Tumor promoting inflammation

Cytokines and inflammatory response (Homo sapiens)

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Cytokines and inflammatory response
Avoiding immune destruction

Interferon type I signaling (Homo sapiens)

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Interferon type I signaling
Therapeutics

lncRNA-mediated mechanisms of therapeutic resistance (Homo sapiens)

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lncRNA-mediated mechanisms of therapeutic resistance
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