Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

Translation inhibitors in chronically activated PDGFRA cells (Homo sapiens)

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Translation inhibitors in chronically activated PDGFRA cells
Evading growth suppressors

Retinoblastoma gene in cancer (Homo sapiens)

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Retinoblastoma gene in cancer
Activating invasion and metastasis

Epithelial to mesenchymal transition in colorectal cancer (Homo sapiens)

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Epithelial to mesenchymal transition in colorectal cancer
Enabling replicative immortality

Notch signaling (Homo sapiens)

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Notch signaling
Inducing angiogenesis

Angiogenesis (Homo sapiens)

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Angiogenesis
Resisting cell death

TP53 network (Homo sapiens)

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TP53 network
Deregulating cellular energetics

Metabolic reprogramming in colon cancer (Homo sapiens)

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Metabolic reprogramming in colon cancer
Genome instability and mutation

ATM signaling (Homo sapiens)

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ATM signaling
Tumor promoting inflammation

Chemokine signaling (Homo sapiens)

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Chemokine signaling
Avoiding immune destruction

Altered glycosylation of MUC1 in tumor microenvironment (Homo sapiens)

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Altered glycosylation of MUC1 in tumor microenvironment
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