Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

Hepatocyte growth factor receptor signaling (Homo sapiens)

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Hepatocyte growth factor receptor signaling
Evading growth suppressors

Tumor suppressor activity of SMARCB1 (Homo sapiens)

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Tumor suppressor activity of SMARCB1
Activating invasion and metastasis

Focal adhesion: PI3K-Akt-mTOR-signaling (Homo sapiens)

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Focal adhesion: PI3K-Akt-mTOR-signaling
Enabling replicative immortality

Wnt signaling (Homo sapiens)

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Wnt signaling
Inducing angiogenesis

Hedgehog signaling (Homo sapiens)

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Hedgehog signaling
Resisting cell death

TP53 network (Homo sapiens)

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TP53 network
Deregulating cellular energetics

TCA cycle nutrient use and invasiveness of ovarian cancer (Homo sapiens)

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TCA cycle nutrient use and invasiveness of ovarian cancer
Genome instability and mutation

Non-homologous end joining (Homo sapiens)

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Non-homologous end joining
Tumor promoting inflammation

IL1 signaling (Homo sapiens)

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IL1 signaling
Avoiding immune destruction

Type II interferon signaling (Homo sapiens)

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Type II interferon signaling
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