Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling Ras signaling (Homo sapiens) Image does not exist Ras signaling	Evading growth suppressors Tumor suppressor activity of SMARCB1 (Homo sapiens) Image does not exist Tumor suppressor activity of SMARCB1	Activating invasion and metastasis Epithelial to mesenchymal transition in colorectal cancer (Homo sapiens) Image does not exist Epithelial to mesenchymal transition in colorectal cancer
Enabling replicative immortality Notch signaling (Homo sapiens) Image does not exist Notch signaling	Inducing angiogenesis PDGF pathway (Homo sapiens) Image does not exist PDGF pathway	Resisting cell death TP53 network (Homo sapiens) Image does not exist TP53 network
Deregulating cellular energetics TCA cycle nutrient use and invasiveness of ovarian cancer (Homo sapiens) Image does not exist TCA cycle nutrient use and invasiveness of ovarian cancer	Genome instability and mutation DNA IR-damage and cellular response via ATR (Homo sapiens) Image does not exist DNA IR-damage and cellular response via ATR	Tumor promoting inflammation IL6 signaling (Homo sapiens) Image does not exist IL6 signaling
Avoiding immune destruction Type II interferon signaling (Homo sapiens) Image does not exist Type II interferon signaling	Therapeutics Imatinib and chronic myeloid leukemia (Homo sapiens) Image does not exist Imatinib and chronic myeloid leukemia