Portal:CPTAC/Hallmarks
From WikiPathways
Sustaining proliferative signaling
Translation inhibitors in chronically activated PDGFRA cells (Homo sapiens) | Evading growth suppressors
G1 to S cell cycle control (Homo sapiens) | Activating invasion and metastasis
Neural crest cell migration in cancer (Homo sapiens) |
Enabling replicative immortality
Notch signaling (Homo sapiens) | Inducing angiogenesis
PDGF pathway (Homo sapiens) | Resisting cell death
TP53 network (Homo sapiens) |
Deregulating cellular energetics
Fatty acid beta-oxidation (Homo sapiens) | Genome instability and mutation
DNA damage response (only ATM dependent) (Homo sapiens) | Tumor promoting inflammation
IL6 signaling (Homo sapiens) |
Avoiding immune destruction
Interferon type I signaling (Homo sapiens) | Therapeutics
lncRNA-mediated mechanisms of therapeutic resistance (Homo sapiens) |