Portal:Disease
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Current revision
Disease Pathways at WikiPathways
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This portal highlights WikiPathways content related to human disease, and is designed as a central organizing point for exploring, curating and expanding the collection of disease pathways. | 
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Get information
Exploring Pathways
- On the right, you'll find a curated set of Featured Pathways, representing all human disease-related pathways at WikiPathways.
- On the left, you'll find a Search box to help find pathways by keywords or gene names.
- Below, you'll find information on how to get involved with pathway curation, to help improve and expand the WikiPathways collection of disease pathways.
Get involved
Create new pathways
- Resources for pathway information: BioCarta, KEGG pathways and Wikipedia.
- Suggested topics: Endocrine and metabolic disease, infectious disease, addiction, immune system disease, neurodevelopmental disorders.
- See our Help section for New Contributor QuickStart, Editor's Palette Guide and Guidelines for Contributors.
Improve existing pathways
Contact us
Send questions about WikiPathways to the wikipathways-discuss mailing list.
How to add a pathway to the portal
The list of Featured Pathways is not static and can be updated at any time. If you know of a pathway that should be added, please contact the administrator.
Pathways from Blau et al.
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View all digitized Pathways from the Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases by Blau et al.
How to add a pathway to the portal
The list of Featured Pathways is not static and can be updated at any time. If you know of a pathway that should be added, please contact Denise Slenter.
COVID-19 Pathways
| invalid pathway title: exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/3/39/WP4860_30155.svg:
SARS-CoV-2 includes a novel Orf10 that interacts with muliple members of the Cullin 2 ubiquitin ligase complex. |
| View all COVID pathways |
Related Portal: Rare diseases
See also the Rare disease portal on WikiPathways
A rare or orphan disease is a disease which affects relatively few people. The exact definition varies between 1:1000 and 1:200.000. E.g. it can be 1:1500 (USA) , 1:2000 (EU) or 1:2500 (Japan). Rare diseases are mostly caused by genetic variation making them chronic and hard to cure. The severity depends on the affected gene and its physiological implications. Rare disease pathways on WikiPathways:
