Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

MET in type 1 papillary renal cell carcinoma (Homo sapiens)

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MET in type 1 papillary renal cell carcinoma
Evading growth suppressors

Retinoblastoma gene in cancer (Homo sapiens)

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Retinoblastoma gene in cancer
Activating invasion and metastasis

TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition (Homo sapiens)

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TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition
Enabling replicative immortality

Regulation of Wnt / B-catenin signaling by small molecule compounds (Homo sapiens)

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Regulation of Wnt / B-catenin signaling by small molecule compounds
Inducing angiogenesis

PDGF pathway (Homo sapiens)

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PDGF pathway
Resisting cell death

TP53 network (Homo sapiens)

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TP53 network
Deregulating cellular energetics

Glycolysis and gluconeogenesis (Homo sapiens)

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Glycolysis and gluconeogenesis
Genome instability and mutation

DNA IR-damage and cellular response via ATR (Homo sapiens)

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DNA IR-damage and cellular response via ATR
Tumor promoting inflammation

IL1 signaling (Homo sapiens)

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IL1 signaling
Avoiding immune destruction

Interferon type I signaling (Homo sapiens)

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Interferon type I signaling
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