Portal:RenalGenomics
From WikiPathways
Welcome to the Renal Genomics Portal
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This portal highlights WikiPathways content related to renal biology and disease. Most available pathways lack tissue/cell specificity and are of limited usefulness in highly differentiated organs such as the kidney. In order to produce quality renal genomics data, new and updated kidney-specific pathways are needed. The Renal Genomics Portal offers an opportunity for renal physiologists to participate in creating, testing and curating new pathways, thereby contributing with modern methodology to integrate the renal knowledge-base. |
Renal Pathways Collection
Renal Pathology
- HIPK2 in kidney fibrosis (Homo sapiens)
- Nephrotic syndrome (Homo sapiens)
- Wnt Signaling in Kidney Disease (Homo sapiens) (Mus musculus)
- Polycystic Kidney Disease Pathway (Homo sapiens)
Glom and Podocyte
- Primary Focal Segmental Glomerulosclerosis FSGS (Homo sapiens) (Mus musculus) (Bos taurus)
- PodNet: protein-protein interactions in the podocyte (Mus musculus)
- XPodNet - protein-protein interactions in the podocyte expanded by STRING (Mus musculus)
Proximal Nephron
- Proximal Tubule Transporters (Rattus norvegicus)
- Hexoses Metabolism in Proximal Tubules (Rattus norvegicus)
- Fructose Metabolism in Proximal Tubules (Rattus norvegicus)
- Polyol Pathway (Homo sapiens) (Mus musculus) (Rattus norvegicus) (Bos taurus)
- Lipid Droplet Metabolism (Rattus norvegicus)
Distal Nephron
- Thick Ascending Limb Transport (Rattus norvegicus)
- Angiotensin Signaling in Thick Ascending Limbs (Rattus norvegicus)
- Vasopressin Regulates Renal Water Homeostasis Via Aquaporins (Homo sapiens)
- Distal Convoluted Tubule 1 (DCT1) Cell (Mus musculus)
Renal cell carcinoma
- Pathways in clear cell renal cell carcinoma (Homo sapiens)
- Type 2 papillary renal cell carcinoma (Homo sapiens)
- MET in type 1 papillary renal cell carcinoma (Homo sapiens)
- Hereditary leiomyomatosis and renal cell carcinoma pathway (Homo sapiens)
- Tumor suppressor activity of SMARCB1(Homo sapiens)
Other pathways
- Renin-Angiotensin System (Rattus norvegicus)
- ACE Inhibitor Pathway (Homo sapiens) (Bos taurus)
- Endothelin Pathways (Homo sapiens) (Bos taurus)
- Vitamin D Metabolism (Homo sapiens) (Bos taurus)
- Vitamin D Metabolism II (Homo sapiens)
Pathways under construction
- Tg26 glom (Mus musculus)
Suggested Contributions
- Membranoproliferative Glomerulonephritis type II
- Acute Kidney Injury
- Chronic Kidney Disease
- Diabetic Nephropathy
- Kidney Transplants and Rejection
- Mitochondria in Renal Disease
- Membranous Nephropathy
- Immune System and the Kidney
- Renovascular Hypertension
- Salt-Sensitive Hypertension
Featured Pathway
Useful Links
- Kidney Precision Medicine Project (KPMP): The KPMP actively engages academics, industry, and the broader scientific community as it works to deepen understanding of the kidneys.
- Epithelial System Biology Laboratory(ESBL): this webpage contains links to many relevant renal systems biology studies.
- Kidney System Biology Project (ESBL): this webpage contains links to renal epithelial transcriptome and proteome databases.
- Supported Software: a list with links and description of bioinformatics tools using WikiPathways.
- Other Pathway repositories: KEGG pathways, BioCarta Reactome.
Get Involved!!
You are invited to test and curate existing pathways as well as to create new ones. All suggestions and contributions are welcome.
How do I do that?
- WikiPathways Overview and Detailed Tutorial
- Learning resources Video Tour, WikiPathways Academy or New Contributor Quickstart
- General help pages
Contact us
- Contact Agustin Gonzalez-Vicente if interested in adding pathways to the Renal Genomics Portal , [1]
- Send general questions about WikiPathways to the wikipathways-discuss mailing list.
