Portal:ExRNA/FeaturedPathways

From WikiPathways

T-Cell Receptor and Co-stimulatory Signaling Takahashi et al. Long non-coding RNA in liver diseases	IL1 and megakaryotyces in obesity Beaulieu et al. Interleukin 1 receptor 1 and interleukin 1beta regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans	miRNA mechanism of action and biogenesis Ozpolat et al. Liposomal siRNA nanocarriers for cancer therapy Thomas et al. Eri1: a conserved enzyme at the crossroads of multiple RNA-processing pathways	Extracellular vesicle-mediated signaling in recipient cells Gangoda et al. Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?
TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer Yang et al. Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer	mir34a and TGIF2 in osteoclastogenesis Krzeszinski et al. miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2	mir219 in Oligodendrocyte Differentiation and Myelination Pusic et al. Youth and environmental enrichment generate serum exosomes containing miR-219 that promote CNS myelination	Apoptosis-related network due to altered Notch3 in ovarian cancer Hu et al. Notch3 pathway alterations in ovarian cancer
miR-222 in Exercise-Induced Cardiac Growth Liu et al. miR-222 Is Necessary for Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling	Hypoxia-mediated EMT and Stemness van den Beucken et al. Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER	DDX1 as a regulatory component of the Drosha microprocessor Han et al. The RNA-binding protein DDX1 promotes primary microRNA maturation and inhibits ovarian tumor progression	EV release from cardiac cells and their functional effects Danielson and Das, Extracellular Vesicles in Heart Disease: Excitement for the Future?
Rac1/Pak1/p38/MMP-2 pathway Gonzalez-Villasana et al. Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer	eIF5A regulation in response to inhibition of the nuclear export system Miyake et al. XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A	MFAP5-mediated ovarian cancer cell motility and invasiveness Leung et al. Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential	LncRNA-mediated mechanisms of therapeutic resistance Parasramka et al. Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma
ApoE and miR-146 in inflammation and atherosclerosis Li et al. Apolipoprotein E enhances microRNA-146a in monocytes and macrophages to suppress nuclear factor-κB-driven inflammation and atherosclerosis	miR-148a/miR-31/FIH1/HIF1α-Notch signaling in glioblastoma Wong et al. The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma	mir-124 predicted interactions with cell cycle and differentiation Shields et al. A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression	miR-517 relationship with ARCN1 and USP1 Shields et al. A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression
miR-509-3p alteration of YAP1/ECM axis Pan et al. miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer	H19 action Rb-E2F1 signaling and CDK-β-catenin activity Ohtsuka et al. H19 Noncoding RNA, an Independent Prognostic Factor, Regulates Essential Rb-E2F and CDK8-β-Catenin Signaling in Colorectal Cancer	mir-193a and MVP in colon cancer metastasis Teng et al. H19 MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression	miRNA regulation of p53 pathway in prostate cancer Moustafa et al. Identification of microRNA signature and potential pathway targets in prostate cancer
miRNA regulation of prostate cancer signaling pathways Moustafa et al. Identification of microRNA signature and potential pathway targets in prostate cancer	LncRNA involvement in canonical Wnt signaling and colorectal cancer Shen et al. To Wnt or Lose: The Missing Non-Coding Linc in Colorectal Cancer	Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer Vannini et al. Transcribed ultraconserved region 339 promotes carcinogenesis by modulating tumor suppressor microRNAs	Extracellular vesicles in the crosstalk of cardiac cells Bei et al. Extracellular Vesicles in Cardiovascular Theranostics.
Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells Datta et al. Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells	miRNAs in the signaling pathway of the immune response in sepsis Giza et al. Cellular and viral microRNAs in sepsis: mechanisms of action and clinical applications	ncRNAs involved in Wnt signaling in hepatocellular carcinoma Klingenberg et al. Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets	ncRNAs involved in STAT3 signaling in hepatocellular carcinoma Klingenberg et al. Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets
PDGFRα and STMN1 cooperate to exacerbate the cytotoxic effects of vinblastine Jun et al. A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine	Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors Mitamara et al. Induction of anti-VEGF therapy resistance by upregulated expression of microseminoprotein (MSMP)	MicroRNA network associated with Chronic lymphocytic leukemia Ciccone and Calin, MicroRNAs in Chronic Lymphocytic Leukemia: An Old Disease with New Genetic Insights	FABP4 in ovarian cancer Gharpure et al, FABP4 as a key determinant of metastatic potential of ovarian cancer
Platelet-mediated interactions with vascular and circulating cells Koupenova et al, Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis	Circulating monocytes and cardiac macrophages in diastolic dysfunction Hulsmans et al, Cardiac macrophages promote diastolic dysfunction	Translational regulation by PDGFRα Zhou et al, Chronic platelet-derived growth factor receptor signaling exerts control over initiation of protein translation in glioma	MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement Leung et al, Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance
Interactions between immune cells and microRNAs in tumor microenvironment Cortez et al, Role of miRNAs in immune responses and immunotherapy in cancer	Alzheimers Disease	Parkinsons Disease	Mir302-367 Promoting Cardiomyocyte Proliferation
MicroRNAs in cardiomyocyte hypertrophy	Image does not exist Integrated Lung Cancer Pathway	miRNA Biogenesis	miRNA targets in ECM and membrane receptors
Fluoropyrimidine Activity	miRNAs involved in DNA damage response	Metastatic Brain Tumor	ErbB Signaling Pathway
Spinal Cord Injury	miRNA Regulation of DNA Damage Response	Parkinsons Disease Pathway (Mus musculus)	Hepatitis C and Hepatocellular Carcinoma
Metastatic brain tumor	Role of Osx and miRNAs in tooth development	miR-127 in mesendoderm differentiation	Mecp2 and Associated Rett Syndrome
miRs in Muscle Cell Differentiation	Cell Differentiation	Signaling Pathways in Glioblastoma	Image does not exist REBF and miR33 in cholesterol and lipid homeostasis
Image does not exist miR-targeted genes in lymphocytes - TarBase TarBase	Image does not exist miR-targeted genes in muscle cell - TarBase TarBase	Image does not exist miR-targeted genes in leukocytes - TarBase TarBase	Image does not exist miR-targeted genes in squamous cell - TarBase TarBase
Image does not exist miR-targeted genes in epithelium - TarBase TarBase	TarBasePathway TarBase	Image does not exist miR-targeted genes in adipocytes - TarBase TarBase	Ectoderm Differentiation
Endoderm Differentiation	Mesodermal Commitment Pathway	SRF and miRs in Smooth Muscle Differentiation and Proliferation

Portal:ExRNA/FeaturedPathways

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