Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

PDGFR-beta pathway (Homo sapiens)

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PDGFR-beta pathway
Evading growth suppressors

Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer (Homo sapiens)

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Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer
Activating invasion and metastasis

TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition (Homo sapiens)

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TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition
Enabling replicative immortality

Regulation of Wnt / B-catenin signaling by small molecule compounds (Homo sapiens)

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Regulation of Wnt / B-catenin signaling by small molecule compounds
Inducing angiogenesis

VEGFA-VEGFR2 signaling (Homo sapiens)

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VEGFA-VEGFR2 signaling
Resisting cell death

Apoptosis (Homo sapiens)

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Apoptosis
Deregulating cellular energetics

Target of rapamycin signaling (Homo sapiens)

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Target of rapamycin signaling
Genome instability and mutation

Nucleotide excision repair (Homo sapiens)

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Nucleotide excision repair
Tumor promoting inflammation

Cytokines and inflammatory response (Homo sapiens)

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Cytokines and inflammatory response
Avoiding immune destruction

Interferon type I signaling (Homo sapiens)

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Interferon type I signaling
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