Portal:CPTAC/Hallmarks

Sustaining proliferative signaling Hippo-Merlin signaling dysregulation (Homo sapiens) Hippo-Merlin signaling dysregulation	Evading growth suppressors G1 to S cell cycle control (Homo sapiens) G1 to S cell cycle control	Activating invasion and metastasis Focal adhesion: PI3K-Akt-mTOR-signaling pathway (Homo sapiens) Focal adhesion: PI3K-Akt-mTOR-signaling pathway
Enabling replicative immortality ncRNAs involved in STAT3 signaling in hepatocellular carcinoma (Homo sapiens) ncRNAs involved in STAT3 signaling in hepatocellular carcinoma	Inducing angiogenesis PDGF pathway (Homo sapiens) PDGF pathway	Resisting cell death TP53 network (Homo sapiens) TP53 network
Deregulating cellular energetics Glycolysis and gluconeogenesis (Homo sapiens) Glycolysis and gluconeogenesis	Genome instability and mutation Non-homologous end joining (Homo sapiens) Non-homologous end joining	Tumor promoting inflammation IL6 signaling pathway (Homo sapiens) IL6 signaling pathway
Avoiding immune destruction Type II interferon signaling (Homo sapiens) Type II interferon signaling	Therapeutics NRF2-ARE regulation (Homo sapiens) NRF2-ARE regulation