Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

Hepatocyte growth factor receptor signaling (Homo sapiens)

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Hepatocyte growth factor receptor signaling
Evading growth suppressors

TGF-beta signaling (Homo sapiens)

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TGF-beta signaling
Activating invasion and metastasis

Epithelial to mesenchymal transition in colorectal cancer (Homo sapiens)

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Epithelial to mesenchymal transition in colorectal cancer
Enabling replicative immortality

Wnt signaling (Homo sapiens)

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Wnt signaling
Inducing angiogenesis

Hedgehog signaling (Homo sapiens)

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Hedgehog signaling
Resisting cell death

Target of rapamycin signaling (Homo sapiens)

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Target of rapamycin signaling
Deregulating cellular energetics

Metabolic reprogramming in colon cancer (Homo sapiens)

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Metabolic reprogramming in colon cancer
Genome instability and mutation

Non-homologous end joining (Homo sapiens)

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Non-homologous end joining
Tumor promoting inflammation

IL6 signaling (Homo sapiens)

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IL6 signaling
Avoiding immune destruction

Altered glycosylation of MUC1 in tumor microenvironment (Homo sapiens)

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Altered glycosylation of MUC1 in tumor microenvironment
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