Portal:CPTAC/Hallmarks

Sustaining proliferative signaling ErbB signaling (Homo sapiens) ErbB signaling	Evading growth suppressors Tumor suppressor activity of SMARCB1 (Homo sapiens) Tumor suppressor activity of SMARCB1	Activating invasion and metastasis Focal adhesion: PI3K-Akt-mTOR-signaling (Homo sapiens) Focal adhesion: PI3K-Akt-mTOR-signaling
Enabling replicative immortality Notch signaling (Homo sapiens) Notch signaling	Inducing angiogenesis PDGF pathway (Homo sapiens) PDGF pathway	Resisting cell death TP53 network (Homo sapiens) TP53 network
Deregulating cellular energetics TCA cycle nutrient use and invasiveness of ovarian cancer (Homo sapiens) TCA cycle nutrient use and invasiveness of ovarian cancer	Genome instability and mutation ATM signaling in development and disease (Homo sapiens) ATM signaling in development and disease	Tumor promoting inflammation IL6 signaling (Homo sapiens) IL6 signaling
Avoiding immune destruction Interferon type I signaling (Homo sapiens) Interferon type I signaling	Therapeutics MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement (Homo sapiens) MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement