Portal:Lipids/FeaturedPathways
From WikiPathways
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(→Sphingolipids [SP]) |
Current revision (11:03, 16 March 2023) (view source) (→Sphingolipids [SP]) |
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| - | Classification based on [https://www.lipidmaps.org/data/classification/LM_classification_exp.php LIPIDMAPS Ontology]: | + | Classification based on [https://www.lipidmaps.org/data/classification/LM_classification_exp.php LIPIDMAPS Ontology]. |
| + | |||
| + | For the September 2022 RDF release, WikiPathways contains: | ||
| + | |||
| + | {| class="wikitable sortable" style="float:left; margin-left: 10px;" | ||
| + | ! Class Name || Abbreviation || Unique Lipids || Unique Pws | ||
| + | |- | ||
| + | | Fatty Acyls || FA || 573 || 274 | ||
| + | |- | ||
| + | | Glycerolipid || GL || 10 || 101 | ||
| + | |- | ||
| + | | Glycerophospholipid || GP || 40 || 48 | ||
| + | |- | ||
| + | | Sphingolipids || SP || 95 || 48 | ||
| + | |- | ||
| + | | Sterol lipids || ST || 182 || 114 | ||
| + | |- | ||
| + | | Prenol Lipids || PR || 50 || 65 | ||
| + | |- | ||
| + | | Saccharolipids || SL || 0 || 0 | ||
| + | |- | ||
| + | | Polyketides || PK || 21 || 18 | ||
| + | |- | ||
| + | |} | ||
| + | |||
| + | |||
== Fatty Acyls [FA] == | == Fatty Acyls [FA] == | ||
| - | |||
| + | For September 2022, WikiPathways contains: | ||
| + | |||
| + | - 573 unique Lipids for human pathways for this Class; try out our [https://bit.ly/3BB6s8t SPARQL query]! | ||
| + | |||
| + | - 274 pathways for humans for this class; adapt the [https://bit.ly/3rgXZTn query] yourself in our SNORQL interface. | ||
=== Fatty Acids [FA01] === | === Fatty Acids [FA01] === | ||
| Line 35: | Line 64: | ||
== Glycerolipids [GL] == | == Glycerolipids [GL] == | ||
| - | + | For September 2022, WikiPathways contains: | |
| + | |||
| + | - 10 unique Lipids for human pathways for this Class; try out our [https://bit.ly/3E1lDeb SPARQL query]! | ||
| + | |||
| + | - 101 pathways for humans for this class; adapt the [https://bit.ly/3C0lBS2 query] yourself in our SNORQL interface. | ||
| + | |||
* [[Pathway:WP4345]] Glycerolipids and Glycerophospholipids from LipidMaps (Mus musculus) and [[Pathway:WP4722]] for Homo Sapiens | * [[Pathway:WP4345]] Glycerolipids and Glycerophospholipids from LipidMaps (Mus musculus) and [[Pathway:WP4722]] for Homo Sapiens | ||
| Line 45: | Line 79: | ||
== Glycerophospholipids [GP] == | == Glycerophospholipids [GP] == | ||
| - | + | For September 2022, WikiPathways contains: | |
| + | |||
| + | - 40 unique Lipids for human pathways for this Class; try out our [https://bit.ly/3fcHULC SPARQL query]! | ||
| + | |||
| + | - 48 pathways for humans for this class; adapt the [https://bit.ly/3BVr4bV query] yourself in our SNORQL interface. | ||
| + | |||
* [[Pathway:WP4345]] Glycerolipids and Glycerophospholipids from LipidMaps (Mus musculus) and [[Pathway:WP4722]] for Homo Sapiens | * [[Pathway:WP4345]] Glycerolipids and Glycerophospholipids from LipidMaps (Mus musculus) and [[Pathway:WP4722]] for Homo Sapiens | ||
* [[Pathway:WP2533]] Glycerophospholipid Biosynthetic Pathway (Homo sapiens) | * [[Pathway:WP2533]] Glycerophospholipid Biosynthetic Pathway (Homo sapiens) | ||
| - | + | * [[Pathway:WP5275]] Ether lipid biosynthesis (Homo sapiens) | |
{| style="margin: 10px" | {| style="margin: 10px" | ||
|width=100px|{{#pwImage:Pathway:WP4345|250px||Glycerolipids and Glycerophospholipids (Mus musculus)}} | |width=100px|{{#pwImage:Pathway:WP4345|250px||Glycerolipids and Glycerophospholipids (Mus musculus)}} | ||
|width=100px|{{#pwImage:Pathway:WP2533|250px||Glycerophospholipid Biosynthetic Pathway (Homo sapiens)}} | |width=100px|{{#pwImage:Pathway:WP2533|250px||Glycerophospholipid Biosynthetic Pathway (Homo sapiens)}} | ||
| + | |width=100px|{{#pwImage:Pathway:WP5275|250px||Ether lipid biosynthesis (Homo sapiens))}} | ||
|} | |} | ||
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== Sphingolipids [SP] == | == Sphingolipids [SP] == | ||
| - | + | For September 2022, WikiPathways contains: | |
| + | - 95 unique Lipids for human pathways for this Class; try out our [https://bit.ly/3r0rTe8 SPARQL query]! | ||
| + | |||
| + | - 48 pathways for humans for this class; adapt the [https://bit.ly/3xKQR5f query] yourself in our SNORQL interface. | ||
'''Mouse (Mus musculus)''' | '''Mouse (Mus musculus)''' | ||
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* [[Pathway:WP4153]] Degradation pathway of sphingolipids, including diseases (Homo sapiens) | * [[Pathway:WP4153]] Degradation pathway of sphingolipids, including diseases (Homo sapiens) | ||
* [[Pathway:WP3933]] Kennedy pathway from Sphingolipids (Homo sapiens) | * [[Pathway:WP3933]] Kennedy pathway from Sphingolipids (Homo sapiens) | ||
| + | * [[Pathway:WP5179]] Biosynthesis and turnover of 1-deoxy-sphingoid bases (Homo sapiens) | ||
{| style="margin: 10px" | {| style="margin: 10px" | ||
| Line 89: | Line 133: | ||
|width=100px|{{#pwImage:Pathway:WP4153|250px||Degradation pathway of sphingolipids, including diseases (Homo sapiens)}} | |width=100px|{{#pwImage:Pathway:WP4153|250px||Degradation pathway of sphingolipids, including diseases (Homo sapiens)}} | ||
|width=100px|{{#pwImage:Pathway:WP3933|250px||Kennedy pathway from Sphingolipids (Homo sapiens)}} | |width=100px|{{#pwImage:Pathway:WP3933|250px||Kennedy pathway from Sphingolipids (Homo sapiens)}} | ||
| + | |width=100px|{{#pwImage:Pathway:WP5179|250px||Biosynthesis and turnover of 1-deoxy-sphingoid bases (Homo sapiens)}} | ||
| + | |} | ||
| + | |||
| + | |||
| + | '''Bacteria''' | ||
| + | * [[Pathway:WP5271]] Bacterial ceramide synthesis (Caulobacter vibrioides) | ||
| + | |||
| + | {| style="margin: 10px" | ||
| + | |width=100px|{{#pwImage:Pathway:WP5271|250px||Bacterial ceramide synthesis (Caulobacter vibrioides)}} | ||
|} | |} | ||
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=== (Chole)sterols [ST01] === | === (Chole)sterols [ST01] === | ||
| + | |||
| + | For September 2022, WikiPathways contains: | ||
| + | |||
| + | - 182 unique Lipids for human pathways for this Class; try out our [https://bit.ly/3qWycPQ SPARQL query]! | ||
| + | |||
| + | - 114 pathways for humans for this class; adapt the [https://bit.ly/3BZNoCc query] yourself in our SNORQL interface. | ||
* [[Pathway:WP430]] Statin Pathway (Homo sapiens) | * [[Pathway:WP430]] Statin Pathway (Homo sapiens) | ||
| Line 140: | Line 199: | ||
== Prenol Lipids [PR] == | == Prenol Lipids [PR] == | ||
| + | |||
| + | For September 2022, WikiPathways contains: | ||
| + | |||
| + | - 50 unique Lipids for human pathways for this Class; try out our [https://bit.ly/3SpDteI SPARQL query]! | ||
| + | |||
| + | - 65 pathways for humans for this class; adapt the [https://bit.ly/3Bu0FkU query] yourself in our SNORQL interface. | ||
| + | |||
| + | === Isoprenoids [PR01] === | ||
| + | |||
| + | * [[Pathway:WP5188]] Retinol metabolism (Homo sapiens) | ||
| + | |||
| + | {| style="margin: 10px" | ||
| + | |width=100px|{{#pwImage:Pathway:WP5188|250px||Retinol metabolism (Homo sapiens)}} | ||
| + | |} | ||
| + | |||
=== Quinones and hydroquinones [PR02] === | === Quinones and hydroquinones [PR02] === | ||
* [[Pathway:WP5037]] Riboflavin and CoQ disorders (Homo sapiens) | * [[Pathway:WP5037]] Riboflavin and CoQ disorders (Homo sapiens) | ||
| + | * [[Pathway:WP5186]] Activation of vitamin K-dependent proteins (Homo sapiens) | ||
{| style="margin: 10px" | {| style="margin: 10px" | ||
|width=100px|{{#pwImage:Pathway:WP5037|250px||Riboflavin and CoQ disorders (Homo sapiens)}} | |width=100px|{{#pwImage:Pathway:WP5037|250px||Riboflavin and CoQ disorders (Homo sapiens)}} | ||
| + | |width=100px|{{#pwImage:Pathway:WP5186|250px||Activation of vitamin K-dependent proteins (Homo sapiens))}} | ||
|} | |} | ||
== Saccharolipids [SL] == | == Saccharolipids [SL] == | ||
| + | |||
| + | No pathway yet for this class; feel free to contribute a pathway representing this lipid class! | ||
== Polyketides [PK] == | == Polyketides [PK] == | ||
| + | For September 2022, WikiPathways contains: | ||
| + | |||
| + | - 21 unique Lipids for human pathways for this Class; try out our [https://bit.ly/3UyZPMO SPARQL query]! | ||
| + | |||
| + | - 18 pathways for humans for this class; adapt the [https://bit.ly/3dwz6Q4 query] yourself in our SNORQL interface. | ||
| + | |||
| + | |||
| + | * [[Pathway:WP4238]] Flavan-3-ol metabolic pathway (Homo sapiens) | ||
| + | |||
| + | |||
| + | {| style="margin: 10px" | ||
| + | |width=100px|{{#pwImage:Pathway:WP4238|250px||Flavan-3-ol metabolic pathway (Homo sapiens)}} | ||
| + | |} | ||
== Signalling Pathways related to Lipids == | == Signalling Pathways related to Lipids == | ||
| Line 159: | Line 250: | ||
* [[Pathway:WP3601]] Composition of Lipid Particles (Homo sapiens) | * [[Pathway:WP3601]] Composition of Lipid Particles (Homo sapiens) | ||
* [[Pathway:WP4522]] Metabolic pathway of LDL, HDL and TG, including diseases (Homo sapiens) | * [[Pathway:WP4522]] Metabolic pathway of LDL, HDL and TG, including diseases (Homo sapiens) | ||
| + | * [[Pathway:WP5272]] LDL- influence on CD14 and TLR4 (Homo sapiens) | ||
| + | * [[Pathway:WP5191]] Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution (Homo sapiens) | ||
{| style="margin: 10px" | {| style="margin: 10px" | ||
| Line 164: | Line 257: | ||
|width=100px|{{#pwImage:Pathway:WP3601|250px||Composition of Lipid Particles (Homo sapiens)}} | |width=100px|{{#pwImage:Pathway:WP3601|250px||Composition of Lipid Particles (Homo sapiens)}} | ||
|width=100px|{{#pwImage:Pathway:WP4522|250px||Metabolic pathway of LDL, HDL and TG, including diseases (Homo sapiens)}} | |width=100px|{{#pwImage:Pathway:WP4522|250px||Metabolic pathway of LDL, HDL and TG, including diseases (Homo sapiens)}} | ||
| + | |width=100px|{{#pwImage:Pathway:WP5272|250px||LDL- influence on CD14 and TLR4 (Homo sapiens)}} | ||
| + | |width=100px|{{#pwImage:Pathway:WP5191|250px||Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution (Homo sapiens)}} | ||
| + | |} | ||
| + | |||
| + | |||
| + | * [[Pathway:WP5192]] Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids (Homo sapiens) | ||
| + | * [[Pathway:WP5182]] Pro-survival signaling of neuroprotectin D1 (Homo sapiens) | ||
| + | * [[Pathway:WP5181]] Roles of ceramides in the development of insulin resistance (Homo sapiens) | ||
| + | * [[Pathway:WP5199]] PtdIns(4,5)P2 in cytokinesis pathway (Homo sapiens) | ||
| + | |||
| + | {| style="margin: 10px" | ||
| + | |width=100px|{{#pwImage:Pathway:WP5192|250px||Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids (Homo sapiens)}} | ||
| + | |width=100px|{{#pwImage:Pathway:WP5182|250px||Pro-survival signaling of neuroprotectin D1 (Homo sapiens)}} | ||
| + | |width=100px|{{#pwImage:Pathway:WP5181|250px||Roles of ceramides in the development of insulin resistance (Homo sapiens)}} | ||
| + | |width=100px|{{#pwImage:Pathway:WP5199|250px||PtdIns(4,5)P2 in cytokinesis pathway (Homo sapiens)}} | ||
|} | |} | ||
Current revision
Classification based on LIPIDMAPS Ontology.
For the September 2022 RDF release, WikiPathways contains:
| Class Name | Abbreviation | Unique Lipids | Unique Pws |
|---|---|---|---|
| Fatty Acyls | FA | 573 | 274 |
| Glycerolipid | GL | 10 | 101 |
| Glycerophospholipid | GP | 40 | 48 |
| Sphingolipids | SP | 95 | 48 |
| Sterol lipids | ST | 182 | 114 |
| Prenol Lipids | PR | 50 | 65 |
| Saccharolipids | SL | 0 | 0 |
| Polyketides | PK | 21 | 18 |
Contents |
Fatty Acyls [FA]
For September 2022, WikiPathways contains:
- 573 unique Lipids for human pathways for this Class; try out our SPARQL query!
- 274 pathways for humans for this class; adapt the query yourself in our SNORQL interface.
Fatty Acids [FA01]
- Pathway:WP4350 Omega 3 & 6 FA synthesis from LipidMaps (Mus musculus) and Pathway:WP4723 for Homo Sapiens
- Pathway:WP4351 Omega 9 and saturated FA synthesis from LipidMaps (Mus musculus) and Pathway:WP4724 for Homo Sapiens
|
Image does not exist Omega 3 & 6 FA synthesis (Mus musculus) |
Image does not exist Omega 9 and saturated FA synthesis (Mus musculus) |
Octadecanoids [FA02]
Eicosanoids [FA03]
- Pathway:WP167 Eicosanoid Synthesis (Homo sapiens)
- Pathway:WP4347 Eicosanoid metabolism via Cyclo Oxygenases (COX) from LipidMaps (Mus musculus) and Pathway:WP4719 for Homo Sapiens
- Pathway:WP4348 Eicosanoid metabolism via Lipo Oxygenases (LOX) from LipidMaps (Mus musculus) and Pathway:WP4721 for Homo Sapiens
- Pathway:WP4349 Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) from LipidMaps (Mus musculus) and Pathway:WP4720 for Homo Sapiens
|
Image does not exist Eicosanoid Synthesis (Homo sapiens) |
Image does not exist Eicosanoid metabolism via Cyclo Oxygenases (COX) (Mus musculus) |
Image does not exist Eicosanoid metabolism via Lipo Oxygenases (LOX) (Mus musculus) |
Image does not exist Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) (Mus musculus) |
Glycerolipids [GL]
For September 2022, WikiPathways contains:
- 10 unique Lipids for human pathways for this Class; try out our SPARQL query!
- 101 pathways for humans for this class; adapt the query yourself in our SNORQL interface.
- Pathway:WP4345 Glycerolipids and Glycerophospholipids from LipidMaps (Mus musculus) and Pathway:WP4722 for Homo Sapiens
|
Image does not exist Glycerolipids and Glycerophospholipids (Mus musculus) |
Glycerophospholipids [GP]
For September 2022, WikiPathways contains:
- 40 unique Lipids for human pathways for this Class; try out our SPARQL query!
- 48 pathways for humans for this class; adapt the query yourself in our SNORQL interface.
- Pathway:WP4345 Glycerolipids and Glycerophospholipids from LipidMaps (Mus musculus) and Pathway:WP4722 for Homo Sapiens
- Pathway:WP2533 Glycerophospholipid Biosynthetic Pathway (Homo sapiens)
- Pathway:WP5275 Ether lipid biosynthesis (Homo sapiens)
|
Image does not exist Glycerolipids and Glycerophospholipids (Mus musculus) |
Image does not exist Glycerophospholipid Biosynthetic Pathway (Homo sapiens) |
Image does not exist Ether lipid biosynthesis (Homo sapiens)) |
Glycerophosphoinositols [GP06]
- Pathway:WP4971 Phosphoinositides metabolism (Homo sapiens)
|
Image does not exist Phosphoinositides metabolism (Homo sapiens) |
Sphingolipids [SP]
For September 2022, WikiPathways contains:
- 95 unique Lipids for human pathways for this Class; try out our SPARQL query!
- 48 pathways for humans for this class; adapt the query yourself in our SNORQL interface.
Mouse (Mus musculus)
- Pathway:WP4344 Sphingolipid Metabolism (general overview) from LipidMaps (Mus musculus) and Pathway:WP4725 for Homo Sapiens
- Pathway:WP4690 Sphingolipids (integrated pathway) from LipidMaps (Mus musculus) and Pathway:WP4726 for Homo Sapiens
|
Image does not exist Sphingolipid Metabolism (Mus musculus) |
Image does not exist Spingolipids (integrated pathway) (Mus musculus) |
Human (Homo sapiens)
- Pathway:WP4142 Metabolism of Spingolipids in ER and Golgi apparatus (Homo sapiens)
- Pathway:WP1423 Ganglio Sphingolipid Metabolism (Homo sapiens)
- Pathway:WP4153 Degradation pathway of sphingolipids, including diseases (Homo sapiens)
- Pathway:WP3933 Kennedy pathway from Sphingolipids (Homo sapiens)
- Pathway:WP5179 Biosynthesis and turnover of 1-deoxy-sphingoid bases (Homo sapiens)
|
Image does not exist Metabolism of Spingolipids in ER and Golgi apparatus (Homo sapiens) |
Image does not exist Ganglio Sphingolipid Metabolism (Homo sapiens) |
Image does not exist Degradation pathway of sphingolipids, including diseases (Homo sapiens) |
Image does not exist Kennedy pathway from Sphingolipids (Homo sapiens) |
Image does not exist Biosynthesis and turnover of 1-deoxy-sphingoid bases (Homo sapiens) |
Bacteria
- Pathway:WP5271 Bacterial ceramide synthesis (Caulobacter vibrioides)
|
Image does not exist Bacterial ceramide synthesis (Caulobacter vibrioides) |
Sterol Lipids [ST]
(Chole)sterols [ST01]
For September 2022, WikiPathways contains:
- 182 unique Lipids for human pathways for this Class; try out our SPARQL query!
- 114 pathways for humans for this class; adapt the query yourself in our SNORQL interface.
- Pathway:WP430 Statin Pathway (Homo sapiens)
- Pathway:WP4190 Mevalonate arm of cholesterol biosynthesis pathway (Homo sapiens)
- Pathway:WP4189 Mevalonate arm of cholesterol biosynthesis pathway with inhibitors (Homo sapiens)
- Pathway:WP4346 Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways) from LipidMaps (Mus musculus) and Pathway:WP4718 for Homo Sapiens
- Pathway:WP4545 Oxysterols derived from cholesterol (Homo sapiens)
|
Image does not exist Statin Pathway (Homo sapiens) |
Image does not exist Mevalonate arm of cholesterol biosynthesis pathway (Homo sapiens) |
Image does not exist Mevalonate arm of cholesterol biosynthesis pathway with inhibitors (Homo sapiens) |
Image does not exist Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways) (Mus musculus) |
Image does not exist Oxysterols derived from cholesterol (Homo sapiens) |
Steroids [ST02]
- Pathway:WP4523 Classical pathway of steroidogenesis with Glucocorticoid and Mineralocorticoid Metabolism (Homo sapiens)
- Pathway:WP4524 The alternative pathway of fetal androgen synthesis (Homo sapiens)
|
Image does not exist Classical pathway of steroidogenesis with Glucocorticoid and Mineralocorticoid Metabolism (Homo sapiens) |
Image does not exist The alternative pathway of fetal androgen synthesis (Homo sapiens) |
Secosteroids [ST03]
- Pathway:WP1531 Vitamin D Metabolism (Homo sapiens)
|
Image does not exist Vitamin D Metabolism (Homo sapiens)) |
Bile acids and derivatives [ST04]
- Pathway:WP4545 Oxysterols derived from cholesterol (Homo sapiens)
|
Image does not exist Oxysterols derived from cholesterol (Homo sapiens) |
Prenol Lipids [PR]
For September 2022, WikiPathways contains:
- 50 unique Lipids for human pathways for this Class; try out our SPARQL query!
- 65 pathways for humans for this class; adapt the query yourself in our SNORQL interface.
Isoprenoids [PR01]
- Pathway:WP5188 Retinol metabolism (Homo sapiens)
|
Image does not exist Retinol metabolism (Homo sapiens) |
Quinones and hydroquinones [PR02]
- Pathway:WP5037 Riboflavin and CoQ disorders (Homo sapiens)
- Pathway:WP5186 Activation of vitamin K-dependent proteins (Homo sapiens)
|
Image does not exist Riboflavin and CoQ disorders (Homo sapiens) |
Image does not exist Activation of vitamin K-dependent proteins (Homo sapiens)) |
Saccharolipids [SL]
No pathway yet for this class; feel free to contribute a pathway representing this lipid class!
Polyketides [PK]
For September 2022, WikiPathways contains:
- 21 unique Lipids for human pathways for this Class; try out our SPARQL query!
- 18 pathways for humans for this class; adapt the query yourself in our SNORQL interface.
- Pathway:WP4238 Flavan-3-ol metabolic pathway (Homo sapiens)
|
Image does not exist Flavan-3-ol metabolic pathway (Homo sapiens) |
Signalling Pathways related to Lipids
- Pathway:WP3965 Lipid Metabolism Pathway (Homo sapiens)
- Pathway:WP3601 Composition of Lipid Particles (Homo sapiens)
- Pathway:WP4522 Metabolic pathway of LDL, HDL and TG, including diseases (Homo sapiens)
- Pathway:WP5272 LDL- influence on CD14 and TLR4 (Homo sapiens)
- Pathway:WP5191 Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution (Homo sapiens)
|
Image does not exist Lipid Metabolism Pathway (Homo sapiens) |
Image does not exist Composition of Lipid Particles (Homo sapiens) |
Image does not exist Metabolic pathway of LDL, HDL and TG, including diseases (Homo sapiens) |
Image does not exist LDL- influence on CD14 and TLR4 (Homo sapiens) |
Image does not exist Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution (Homo sapiens) |
- Pathway:WP5192 Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids (Homo sapiens)
- Pathway:WP5182 Pro-survival signaling of neuroprotectin D1 (Homo sapiens)
- Pathway:WP5181 Roles of ceramides in the development of insulin resistance (Homo sapiens)
- Pathway:WP5199 PtdIns(4,5)P2 in cytokinesis pathway (Homo sapiens)
|
Image does not exist Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids (Homo sapiens) |
Image does not exist Pro-survival signaling of neuroprotectin D1 (Homo sapiens) |
Image does not exist Roles of ceramides in the development of insulin resistance (Homo sapiens) |
Image does not exist PtdIns(4,5)P2 in cytokinesis pathway (Homo sapiens) |
